Separation method of 1,3-propylene glycol fermentation liquid

A separation method and technology of fermented liquid, applied in 1 field, can solve problems such as hindering the evaporation of fractions and high salt content

Active Publication Date: 2010-11-03
PETROCHINA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to solve some problems existing in the current 1,3-propanediol fermentation broth separation process, such as higher salt content, problems such as salt crystall

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1) First, filter out the bacteria in the fermentation broth with a ceramic membrane to obtain 40.05 kg of clear liquid without biological cells;

[0018] 2) the gained clear liquid is evaporated and concentrated to 6kg;

[0019] 3) Add 3kg of evaporated concentrate to the alcohol precipitation tank, add 6kg of 95% industrial ethanol, then start the stirring motor, and program cooling while stirring. When it reaches 32°C, add 18g of sodium acetate, and continue the program cooling. The cooling rate is 12°C / h, the temperature drops to 0°C, stop stirring;

[0020] 4) After standing for 5 hours, remove the precipitate by centrifugation to obtain the supernatant;

[0021] 5) The obtained supernatant is pumped into the rectification tower to reclaim ethanol, the ethanol purity obtained at the top of the tower is 95%, and the tower kettle enters the light removal tower;

[0022] 6) The light removal tower is operated under the condition of vacuum degree of 0.08-0.09MPa, the ...

Embodiment 2

[0029] 1) First, filter out the bacteria in the fermentation broth with a ceramic membrane to obtain 38.5 kg of clear liquid without biological cells;

[0030] 2) the gained clear liquid is evaporated and concentrated to 5.8kg;

[0031] 3) Put 1kg of evaporated concentrated liquid into the alcohol precipitation tank, add 2kg of methanol, then start the stirring motor, and program cooling while stirring. h, the temperature dropped to 0°C, and the stirring was stopped;

[0032] 4) After standing for 5 hours, remove the precipitate by centrifugation to obtain the supernatant;

[0033] 5) The obtained supernatant is pumped into the rectification tower to reclaim methanol, the methanol purity obtained at the top of the tower is 97%, and the tower still enters the light removal tower;

[0034] 6) The light removal tower is operated under the condition of vacuum degree of 0.08-0.09MPa, the light components with a volatility greater than 1,3-propanediol are extracted from the top of...

Embodiment 3

[0038] Add 1 kg of the concentrated solution described in step 2) of Example 2 into the alcohol precipitation tank, add 95% industrial ethanol and 1 kg of methanol, and the remaining steps are the same as in Example 2.

[0039] In step 7), the actual temperature of the tower kettle was 175° C., the purity of the obtained 1,3-propanediol product was 98%, and the yield of the separation process was 80%.

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PUM

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Abstract

The invention relates to a separation method of 1,3-propylene glycol fermentation liquid, comprising the following steps: removing thallus in the fermentation liquid through centrifugation or membrane filtration to obtain clear liquid; carrying out evaporation concentration on the clear liquid into a half of one twelfth of the original volume to obtain mother liquid; adding one or more C1-C4 alcohol or C3-C5 ketone based on the volume ratio of 1:0.5-1:5, cooling to 30-35 DEG C, and then adding a seed crystal, wherein the mass of the seed crystal is 0.05-1% of that of the mother liquid; continuously cooling to minus10-10 DEG C with the velocity of 2-20 DEG C/h, separating out precipitate, extracting the clear liquid through a side line or filtering or removing the precipitate by centrifugation with the velocity of 1000-5000rpm, taking supernate, and then recovering the alcohol or the ketone by distillation or rectification; and finally decompressing and rectifying to obtain 1,3-propylene glycol. The separation method has simple process and operation, high product yield and high purity; and the method can be widely applied to producing the 1,3-propylene glycol product by a fermentation method.

Description

Technical field: [0001] The invention belongs to the technical field of biological separation engineering and relates to the separation technology of microbial fermentation liquid, in particular to a separation method of 1,3-propanediol fermentation liquid. Background technique: [0002] The production methods of 1,3-propanediol can be roughly divided into 3 types, of which there are 2 types of petrochemical routes, namely: the ethylene oxide carbonylation method developed by Shell Company with ethylene oxide as raw material and the ethylene oxide carbonylation method developed by Degussa Company The first is the acrolein hydration hydrogenation method using propylene as the raw material; the third is the microbial fermentation method using renewable resources as the raw material. [0003] In the production of 1,3-propanediol by microbial fermentation, in addition to the target product 1,3-propanediol, there are acetic acid, ethanol, 2,3-butanediol, lactic acid, succinic aci...

Claims

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Application Information

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IPC IPC(8): C07C31/20C07C29/76C07C29/80
Inventor 徐育烨徐友海刘海军吕继萍刘姜金刚董鑫
Owner PETROCHINA CO LTD
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