Method for preparing flamazine/bacterial cellulose composite wound dressing

A technology of silver sulfadiazine and bacterial cellulose, which is applied in the field of biomedical materials and medical devices, can solve the problems of lack of competitiveness of high-end products, no series of products, poor water permeability and moisture absorption, etc., and achieves controllable particle size distribution, good Good antibacterial activity, antibacterial effect
CN101905031AActive Publication Date: 2010-12-08UNIV OF SCI & TECH BEIJING +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
UNIV OF SCI & TECH BEIJING
Publication Date
2010-12-08

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Abstract

The invention provides a method for preparing flamazine / bacterial cellulose composite wound dressing, which comprises the following steps of: performing pretreatment and purification treatment on a bacterial cellulose membrane to obtain purified bacterial cellulose; preparing flamazine suspension with the granularity of 50 to 5,000 nm under dark condition; reacting the bacterial cellulose membrane with the flamazine suspension to form a flamazine / bacterial cellulose composite membrane; and performing drying treatment to obtain a dry flamazine / bacterial cellulose composite membrane, or performing extruding dehydration to obtain a wet flamazine / bacterial cellulose composite membrane with different water content values to prepare the flamazine / bacterial cellulose composite wound dressing. The prepared flamazine / bacterial cellulose composite wound dressing has high mechanical performance, high antibacterial property, and high water and air permeability or good drainage and moisture absorption effects, can promote the drying, scabbing and healing of wound, and is used for preventing and treating the secondary wound infection of second-degree and third-degree burn or scald.
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Description

technical field

[0001] The invention relates to the related fields of biomedical materials and medical devices, in particular to a preparation method and application of a silver sulfadiazine / bacterial cellulose composite wound dressing. Background technique

[0002] Silver Sulfadiazine (Silver Sulfadiazine), N-2-pyrimidinyl-4-aminobenzenesulfonamide silver salt Molecular formula: C 10 h 9 AgN 4 o 2 S, white or off-white crystalline powder; easy to deteriorate when exposed to light or heat. Silver sulfadiazine is insoluble in water, ethanol, chloroform or ether.

[0003] Silver sulfadiazine is a commonly used drug for the prevention and treatment of burn wound infection, and the commonly used clinical dosage forms include cream, ointment, suspension, powder and so on. Silver sulfadiazine is a short-acting sulfa drug for the treatment of systemic infections, which has the antibacterial effect of sulfadiazine and the astringent effect of silver salt. It has a wide antibac...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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