Antiphlogistic and analgesic traditional Chinese medicine extract and preparation method thereof
The technology of extract and traditional Chinese medicine is applied in the field of oleicaceae ash tree stem bark extract and preparation thereof, anti-inflammatory and analgesic traditional Chinese medicine extract and preparation field thereof, and can solve the problems of large toxic and side effects, large dosage and high quality. Instability and other problems, to achieve the effect of less toxic and side effects, easy recovery, and low cost of raw materials
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0017] The effect of embodiment 1 Chinese medicine extract on mouse ear swelling caused by xylene
[0018] 1 test material
[0019] 1.1 Experimental animals: Kunming mice, weighing 18-20 g, provided by Qinglongshan Animal Breeding Farm, Jiangning District, Nanjing.
[0020] 1.2 Positive control drug: aspirin, Jiangsu Pingguang Pharmaceutical Co., Ltd.
[0021] 1.3 Test reagents: methanol, ethanol, petroleum ether: Sinopharm Chemical Reagent Co., Ltd., analytically pure. Distilled water is provided by the laboratory of the school. Normal saline, configured in this laboratory.
[0022] 1.4 Preparation of traditional Chinese medicine extract 1
[0023] (1) Drying: the bark of the wax tree is dried in an oven at 80°C;
[0024] (2) pulverizing: the dry stem bark is pulverized, and crosses a 20-mesh sieve to obtain powder;
[0025] (3) Extraction: Take 2 kg of powder, add water 25 times the weight of the medicinal material powder for the first time, soak for 1 hour, decoct for...
Embodiment 2
[0059] The influence of embodiment 2 Chinese medicine extracts on mouse writhing reaction caused by acetic acid
[0060] 1 test material
[0061] 1.1 Experimental animals: Same as above.
[0062] 1.2 Positive control drugs: same as above.
[0063] 1.3 Test reagents: Same as above.
[0064] 2 Experimental methods
[0065] 50 mice, ♀ Half and half were randomly divided into 14 groups: negative control group (normal saline), positive control group (aspirin) and high, middle and low dose groups of Chinese herbal extracts 1, 2, 3 and 4. The mice in each group were intragastrically administered the corresponding drugs, once a day, for 7 consecutive days, 60 minutes after the last administration, 0.6% glacial acetic acid 10ml / kg body weight was injected into the abdominal cavity, and the number of writhing of the mice was observed within 15 minutes. The writhing is characterized by a concave abdomen, extended torso and hind legs, and raised arms. Calculation of inhibition rate...
Embodiment 3
[0073] The toxicity test of embodiment 3 Chinese medicine extract
[0074] 1 Experimental materials
[0075] 1.1 Animals: Same as above.
[0076] 1.2 Test reagents: Same as above.
[0077] 1.3 Preparation of traditional Chinese medicine extract 5
[0078] (1) Drying: the bark of the wax tree is dried in an oven at 40°C;
[0079] (2) pulverizing: the dry stem bark is pulverized, and crosses a 40-mesh sieve to obtain powder;
[0080] (3) Extraction: Take 2 kg of powder, add water 30 times the weight of the medicinal material powder for the first time, soak for 2 hours, decoct for 3 hours, filter; add water 8 times the weight of the medicinal material powder to the filter residue, and decoct for 1 hour , filter, and combine 2 filtrates;
[0081] (4) concentrating under reduced pressure: the filtrate is concentrated under reduced pressure into an extractum, so that the relative density of the extractum is 1.10g / ml;
[0082] (5) Purification: Add an equal volume of petroleum ...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More