Kiwi fruit extract and extraction method and application thereof

Abstract

The invention relates to a kiwi fruit extract and an extraction method and an application thereof. The extraction method of the kiwi fruit extract includes that fresh kiwi fruits with skins are cut up, the cut fresh kiwi fruits are heated by methanol and subjected to reflux extraction for two times, the first time of the reflux extraction is performed for 1.5 hours to 2.5 hours, the second time of the reflux extraction is performed for 0.5 hour to 1.5 hours, the twice extracting solutions are combined, filtered and concentrated to obtain a kiwi fruit methanol total extract, the kiwi fruit methanol total extract is subjected to extraction by petroleum ether, ethyl acetate and n-butyl alcohol sequentially, and after reduced pressure suction filtration and concentration, a kiwi fruit petroleum ether extracting part, an ethyl acetate extracting part and an n-butyl alcohol extracting part are respectively obtained. According to internal experiment, acarbose serves as positive control, the therapeutic effect of the kiwi fruit petroleum ether, the ethyl acetate and the n-butyl alcohol extracting parts on a diabetic mouse which is induced by alloxan is observed, and the experimental result shows that a certain therapeutic effect of kiwi fruit ACPE, ACEA and ACBU on the diabetic mouse which is induced by the alloxan is achieved.

Description

technical field [0001] The present invention relates to a kind of kiwi fruit extract, in addition, also relates to a kind of extraction method of this kiwi fruit extract, and its application in the preparation aspect of hypoglycemic medicine; The use of drugs in lowering blood sugar. Background technique [0002] Kiwi fruit is the fruit of Actinidia chinensis Planch, also known as vine pear, kiwi pear, sheep fruit, etc. It is born in mountain forests or bushes, and is often entwined on other things. Distributed in South Central and Shaanxi, Jiangsu, Anhui, Zhejiang, Jiangxi, Fujian, Sichuan, Guizhou, Yunnan and other places, it tastes sour, sweet, and cold in nature. Return to the stomach. Liver, kidney channel. It has the functions of antipyretic, quenching thirst, invigorating the stomach, and treating stranguria. Indications for dysphoria, diabetes, dry cough due to lung heat, indigestion, damp-heat jaundice, stone stranguria, hemorrhoids. After consulting the litera...

AI Technical Summary

Problems solved by technology

Among diabetic patients, more than 90% of diabetic patients belong to type Ⅱ diabetes. At present, oral hypoglycemic drugs are mainly used to control fasting blood sugar to achieve therapeutic purposes. For a long time, therapeutic drugs have mainly focused on insulin secretory agents such as sulfonylureas libenclamide, glipizide), mainly used to reduce blood sugar in normal people or diabetic patients whose insulin function has not been completely lost; drugs that enhance peripheral glucose utilization, such as biguanides (phenformin, metformin), are effective for Diabetic patients with pancreatic islet function all have hypoglycemic effects. These two types of drugs will also bring relatively large side effects while lowering fasting blood sugar, and have no obvious effect on lowering postprandial blood sugar.

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