Nano magnetic fluid composite material coated with polyamino acid and preparation method thereof

Abstract

The invention discloses a polyamino acid coated nano-magnetic fluid composite material and a preparation method for the same, and belongs to the technical field of magnetic fluids. A polyaspartic acid obtained by the hydrolysis of polysuccinimide is coated on the surface of a magnetic ferroferric oxide nano-particle, a part of carboxyl groups are coupled with the ferroferric oxide nano-particle, and a part of carboxyl groups are free outside the particle. The polyamino acid coated nano-magnetic fluid composite material can be obtained by reacting a 6,000-molecular weight mixed solution of the polysuccinimide and a solution of sodium hydroxide with FeCl3 and Fe(NH4)2(SO4)2 in a Teflon reaction kettle, and performing separation and washing. The material synthesized by the method is high in crystallinity and magnetism and quick in T2 weighted signal response.

Description

Technical field

[0001] The invention relates to a polyamino acid-coated ferroferric oxide nanomagnetic fluid composite material and a preparation method thereof, belonging to the field of magnetic fluid technology, and particularly relates to medical applications. Technical background

[0002] Nanomaterials refer to nanoparticles with a size between 1-100nm. And it has some special effects that are different from conventional objects, such as small size effect, surface effect, quantum size effect, and macroscopic quantum orbit effect. The properties of magnetic nanomaterials are different from conventional magnetic materials because the characteristic physical lengths related to magnetism are exactly in the nanometer range, such as: magnetic single domain size, superparamagnetic critical size, exchange interaction length, and electron mean free path are roughly on the order of 1-100nm. When the size of the magnetic body is equivalent to these characteristic physical lengths...

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