The invention provides a comprehensive method for soil conditioning and restoration. The method comprises the following steps: before crops are planted or after fruit trees are harvested, oyster shellpowder, silicon-calcium-potassium-magnesium fertilizer, biological organic fertilizer, a biological control agent and ternary compound fertilizer are applied to soil; before the fruit trees are sprouted and bloomed, a macroelement water-soluble fertilizer and humic acid water-soluble fertilizer are applied to the soil; during a swelling period of young fruits of the fruit trees, silicon-calcium-potassium-magnesium fertilizer and a composite microbial bacterial liquid are applied to the soil; and during a fruit strengthening period of the fruit trees, high-potassium fertilizer and seaweed fertilizer are applied to the soil. The method is used for conditioning and restoring the soil, so that the pH of the soil tends to be neutral, and the acidification degree is obviously reduced; the organic matter content of the soil is obviously increased, the soil becomes loose and breathable, and the soil layer is deep and thick; and the heavy metal content in the soil is reduced, so that securityof the planted crops is improved, and the yield is improved. The method provided by the invention does not interrupt growth of the crops in the soil, enables the crops to grow healthily while conditioning and restoring the soil, and improves quality of the crops, so that economic benefits of growers are guaranteed.