Application of novel slide buckle bio-absorbable stent

Abstract

The invention relates to an application of a novel slide buckle bio-absorbable stent in manufacture of a cardiovascular system or a lumen stent for cardiovascular or luminal stenosis diseases. The application has the advantages as follows: the novel slide buckle bio-absorbable stent has good degradability and biocompatibility and is applicable to pediatric intravascular stents, and late stent thrombosis cannot occur after implantation, so that antiplatelet drugs are not required to be taken for a long time, and possible subsequent surgical operations cannot be affected; the support force is high, the novel slide buckle bio-absorbable stent can be taken as a cardiovascular system stent or a lumen stent and can be widely applied in the cardiovascular or luminal stenosis diseases; the manufacture is simple and convenient, medicine carrying is facilitated, and the stent can be used as a drug or gene therapy carrier; the stent is equipped with a delivery system at the same time, and the operation difficulty is reduced; and a large number of animal experiments show that the novel slide buckle bio-absorbable stent has a higher success rate during the usage, the curative effect is remarkable, and the stent has a better clinical application prospect.

Description

[0001] This application is a divisional application with an application date of November 12, 2010, application number 201010543488.4, and an invention titled "A Novel Sliding Buckle Bioabsorbable Stent and Its Application". technical field [0002] The invention relates to a medical device, in particular to the application of a novel sliding buckle bioabsorbable bracket. Background technique [0003] Congenital heart disease (hereinafter referred to as congenital heart disease) is the most common cardiovascular disease in childhood, with an incidence rate of 0.678% of live births. Congenital heart disease in infants and young children is accompanied by congenital pulmonary artery and pulmonary Stenosis of arteries and their branches accounts for 7%-15% of all congenital heart diseases, and right ventricle-pulmonary artery artificial conduit (RV-PA conduit) stenosis after acquired surgery, postoperative restenosis of pulmonary artery and pulmonary vein, systemic vein and aorta...

AI Technical Summary

Problems solved by technology

However, the fixed size of the metal stent will not change with the growth of the blood vessel after implantation, and it is easy to cause artificial stenosis due to the mismatch with the size of the blood vessel in the later stage. It is especially not suitable for pediatric vascular stents for children with growth characteristics.

[0006]The metal stent also has the following defects: (1) It is prone to thrombosis and requires long-term antiplatelet therapy; (2) It stays in the human body for a lifetime, affecting subsequent possible surgical procedures Surgical treatment; (3) artifacts appear in MRI and CT examinations; (4) may change the geometric configuration of blood vessels to block branches; (5) hinder the subsequent reconstruction and expansion of the lumen; Lack of tightness of the tube wall often results in small gaps remaining after implantation

However, there is no report on the new type of sliding buckle bioabsorbable stent with strong support and easy manufacture and use, and its application as a cardiovascular system stent or luminal stent in cardiovascular or luminal stenosis diseases.

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