A coagulant and intravascular thrombectomy device

Abstract

The invention relates to a coagulating agent and an intravascular thrombus taking device, and can be used for planting in blood vessels to treat blood vessel thrombosis lesion such as cerebral apoplexy and the like. The intravascular thrombus taking device comprises the coagulating agent and a thrombus taking unit, and a main component of the coagulating agent is alkylcyanoacrylate. The intravascular thrombus taking device can conveniently and quickly take out thrombus, and is safe and effective.

Description

technical field [0001] The invention relates to a coagulant and an intravascular thrombus removal device, which can be used for implanting blood vessels to treat vascular embolism diseases, such as cerebral apoplexy and the like. The device is a convenient and fast intravascular thrombectomy system. Background technique [0002] Vascular embolism is a common condition in vascular diseases. For example, acute ischemic stroke is the damage of nerve tissue caused by ischemic necrosis of local brain tissue caused by sudden blockage of blood flow in the brain. 70% to 80% of patients with severe symptoms requiring arteriography can see emboli or thrombus obstruction, and the fatality rate of embolism in larger vessels is 53% to 92%. Vascular recanalization is the key to the treatment of acute ischemic stroke. At present, the treatment methods for such diseases mainly include drug thrombolysis and mechanical thrombectomy. However, from the perspective of the effect of clinical t...

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Problems solved by technology

[0003] The main problems of drug thrombolysis are as follows: if it is administered systemically, it is easy to cause bleeding complications, and during the process of thrombolysis, the size of the embolus shrinks and it is easy to block the downstream blood vessels with smaller diameters; if interventional thrombolysis (interventional thrombolysis Thrombosis refers to injecting a thrombolytic agent into the vicinity of the lesion in the blood vessel where the lesion is located through a catheter, forming a high concentration of the thrombolytic agent in the local lesion instantly, accelerating the speed of thrombus dissolution, and increasing the chance of blood vessel recanalization. ), for most blood clots that are too large in absolute size and can resist digestion by enzymes, a very large dose of thrombolytic drugs is required to dissolve them, and a relatively long treatment time window is required, which is easy to cause various complication with higher risk

[0004] The development of mechanical thrombectomy has gone through the following methods: thrombectomy, which is more thorough in removing thrombus, but causes too much damage to the vessel wall and can easily cause various concurrent inflammations; laser thrombectomy is difficult to operate, and the laser energy If the energy is too low, it will be ineffective, if the energy is too high, it will damage the blood vessels, and it is also easy to cause various complications; the thrombus removal with the trapping net is easy to operate, but it cannot be used in small intracranial blood vessels due to its large size; The plug is easy to operate and causes little damage to the vessel wall, but it is easy to destroy the plug when the catcher captures the plug, resulting in smaller plugs

After the catcher captures the emboli, it is also easy to break the emboli during the extraction process, and the small emboli will continue to block the small blood vessels

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