Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of silver-bearing foam material for wound dressing

A foam material, wound dressing technology, applied in medical science, bandages, absorbent pads, etc., to achieve good antibacterial function, broad market prospects, and improve the effect of product antibacterial function

Inactive Publication Date: 2014-04-23
褚加冕
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are few reports on polyvinyl alcohol porous foam at home and abroad, mainly focusing on the research of pure polyvinyl alcohol foam, and the chitin / polyvinyl alcohol porous foam without adding silver particles. The existing technology greatly improves product production efficiency and product antibacterial function

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment one: preparation and shortening of production time of silver-containing chitin / polyvinyl alcohol composite foam material, by weight, after dissolving polyvinyl alcohol 6%, chitin 4% and distilled water 62.5% at 80 ℃, to Add 17% sulfuric acid, 3.5% formaldehyde, 2% sodium bicarbonate, and 5% silver particles to the solution, then pour the blend into a mold, thermoform it in an oven at 72°C, and finally wash it. The degree of polymerization of polyvinyl alcohol is controlled at 1800-1900, and 5 batches are tested. The average thermoforming time is 3.1h, while the degree of polymerization of polyvinyl alcohol is 1900-2600, and the average thermoforming time is 6-8h. 1800-1900 polyvinyl alcohol can significantly shorten the production time.

Embodiment 2

[0014] Embodiment 2: silver-containing chitin / polyvinyl alcohol composite foam material inhibits bacterial detection, by weight, after heating and dissolving polyvinyl alcohol 5.2%, chitin 3% and distilled water at 80°C, add to the solution 15% sulfuric acid, 3.8% formaldehyde, 2% sodium bicarbonate, 2% silver particles, after fully mechanically stirring, pour the blend into a mold, thermoform in an oven at 72°C for 3.5 hours, and finally wash to obtain silver-containing chitin / polyvinyl alcohol syntactic foam. Take the prepared foam material, under the condition of rotation speed 200rpm / min, 25 ℃, and the flask shaking method for 1h action time, 4 batches are detected: the silver-containing chitin / polyvinyl alcohol composite foam material has good antibacterial properties, and it has good antibacterial properties against gold. The antibacterial rates of Staphylococcus aureus were 97%, and the antibacterial rates of Candida albicans were 93%.

Embodiment 3

[0015] Embodiment 3: silver-containing chitin / polyvinyl alcohol composite foam material is used for wound healing, by weight, after heating and dissolving polyvinyl alcohol 5.2%, chitin 3% and distilled water at 80°C, add it to the solution Add 15% of sulfuric acid, 3.8% of formaldehyde, 2% of sodium bicarbonate, 2% of silver particles, fully mechanically stir, pour the blend into a mold, heat-form in an oven at 72°C for 3.5 hours, and finally wash to obtain a silver-containing carapace Vegan / polyvinyl alcohol syntactic foam. After γ-ray sterilization, the material was covered on the surface of 6 patients' skin wounds, and the average healing time was 7 days, while the healing time of conventional dressings such as gauze was 16 days.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
The average particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of a silver-bearing foam material for wound dressing. The preparation method comprises the following steps: I, proportioning: weighing the following raw materials in percentage by weight: 2-7% of chitin, 5-7% of polyvinyl alcohol, 15-20% of sulfuric acid, 3-4% of formaldehyde, 1-3% of sodium hydrogen carbonate, 0.1-10% of silver particles and the balance of distilled water; II, thermally dissolving polyvinyl alcohol: first, heating and dissolving chitin, polyvinyl alcohol and distilled water to obtain mixed liquor, wherein the heating temperature is 83-93 DEG C; III, compounding chitin: adding sulfuric acid, formaldehyde and sodium hydrogen carbonate into the mixed liquor to blend and mix, and then adding the silver particles; IV, pouring the blend in the step III into a mould to be thermally moulded, wherein the thermal moulding temperature is 70-85 DEG C and the thermal moulding time is 3-4 hours; V, cleaning a thermally moulded product to obtain a chitin / polyvinyl alcohol composite foam material.

Description

technical field [0001] The invention relates to a preparation method of a silver-containing foam material used for wound dressing. Background technique [0002] Chitin has high molecular weight, non-toxicity, good biocompatibility, degradability, has the function of promoting wound healing and hemostasis, and is a relatively good biomedical material. There are many hydroxyl groups and some acetylamino groups distributed on the macromolecular chain of chitin, which has a stable coordination effect on many metal ions and has important applications in water treatment. Silver particles have antibacterial and bactericidal functions. At present, there are few reports on polyvinyl alcohol porous foam at home and abroad, mainly focusing on the research of pure polyvinyl alcohol foam, and the chitin / polyvinyl alcohol porous foam without adding silver particles. The existing technology greatly improves product production efficiency and product antibacterial function. Contents of t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L15/28A61L15/24A61L15/42A61L15/44
Inventor 褚加冕褚省吾陈达永欧阳溪徐慧君
Owner 褚加冕