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Composition with function of removing chloasma and preparation method of composition with function of removing chloasma

A technology for removing chloasma and a composition, which is applied in the directions of medical preparations containing active ingredients, food preparation, and drug combinations, etc., can solve the problem of unclear reasons for melanocyte function, affecting the work and life of patients, and complex pathogenesis. and other problems, to achieve the effect of simple and feasible preparation process, improvement of facial chloasma, and strong pertinence

Inactive Publication Date: 2014-12-03
BEIJING ZHONGTAI TIANHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although patients with chloasma have no subjective symptoms, it affects their appearance, seriously affects their work and life, and creates a serious psychological burden on them
[0003] According to modern medicine, the pathogenesis of chloasma is extremely complicated. There is no history of local inflammation and trauma before the onset. The histological characteristics are mainly the increase of melanin and melanosomes in the epidermis, and the enhancement of melanocyte activity, but the real change of melanocyte The reason for the function is unclear

Method used

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  • Composition with function of removing chloasma and preparation method of composition with function of removing chloasma
  • Composition with function of removing chloasma and preparation method of composition with function of removing chloasma
  • Composition with function of removing chloasma and preparation method of composition with function of removing chloasma

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Experimental program
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Effect test

Embodiment 1

[0034] Formula: Salvia miltiorrhiza extract 117g, angelica extract 67g, rose flower extract 50g, lycopene 17g, vitamin E powder 17g, microcrystalline cellulose 274g, crospovidone 25g, croscarmellose sodium ( (additional) 30g, magnesium stearate (additional) 3g, film coating premix 18g.

[0035] Preparation:

[0036] 1. The lycopene in the formula is passed through a 40-mesh sieve, and the rest of the raw and auxiliary materials are respectively passed through a 80-mesh sieve for later use. The production water is purified water, which should meet the requirements of purified water in the "Chinese Pharmacopoeia" 2010 edition, and the ethanol used in production is edible grade ethanol, which should meet the requirements of GB 10343-2008 edible alcohol.

[0037] 2. Accurately weigh the salvia miltiorrhiza extract, angelica extract, rose flower extract, lycopene, vitamin E powder, microcrystalline cellulose and cross-linked povidone according to the dosage of the formula, mix the...

Embodiment 2

[0043] Formula: Salvia miltiorrhiza extract 175.5g, angelica extract 33.5g, rose flower extract 42g, lycopene 8.5g, vitamin E powder 8.5g, dextrin 232g.

[0044] Preparation method: mix the raw and auxiliary materials evenly, sieve, granulate to make granules, pack and inspect to obtain products that meet the standards.

Embodiment 3

[0046] Formula: Salvia miltiorrhiza extract 58.5g, angelica extract 83.5g, rose flower extract 75g, lycopene 25.5g, vitamin E powder 25.5g, microcrystalline cellulose 89g, magnesium stearate 3g.

[0047] Preparation method: mix the raw and auxiliary materials evenly, pour into capsules to make capsules, pack and inspect to obtain products that meet the standards.

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Abstract

The invention discloses a composition with a function of removing chloasma and a preparation method of the composition with the function of removing the chloasma. The composition is mainly prepared from the following raw materials in parts by weight: 58.5-175.5 parts of a salvia miltiorrhiza extract, 33.5-100.5 parts of a Chinese angelica extract, 25-75 parts of a rose extract 8.5-25.5 parts of lycopene and 8.5-25.5 parts of vitamin E powder. The raw materials of the composition have the antioxidant ability and can be used for effectively improving a chloasma condition on the face of a patient, improving the microcirculation on the face, fading away stains, obviously lowering the area and chromaticity of the chloasma on the face of the patient. According to a human feeding trial, the composition has better chloasma removing effects in comparison with a single salviae miltiorrhizae extract preparation and a single Chinese angelica extract preparation under the same use amount, and is suitable for the use by vast chloasma patients.

Description

technical field [0001] The invention relates to a composition with the function of removing chloasma and a preparation method thereof, belonging to the technical field of health food. Background technique [0002] Chloasma is an acquired pigmentation disease. Flake brown and tan patches appear on the face, symmetrically pigmented, butterfly-wing-shaped, and scattered on both sides of the cheeks in spots and flakes, seen on the lower and outer sides of the eyes. In severe cases It spreads all over the face like a mask, and is one of the clinically common and difficult-to-cure skin diseases. The motherland medicine calls it "face dust", "dark spots", "butterfly spots" and so on. The prevalence of chloasma in the natural population is 60%, mostly in young and middle-aged women. With the quickening pace of modern life and the increasing pressure of people's life and work, its incidence rate is getting higher and higher. Although patients with chloasma have no subjective sympto...

Claims

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Application Information

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IPC IPC(8): A23L1/29A61K36/738A61P17/00A61P39/00A61K31/01A61K31/355A23L33/00
CPCA61K36/537A23V2002/00A61K9/08A61K9/16A61K9/28A61K9/48A61K31/01A61K31/355A61K36/232A61K36/738
Inventor 何俊保
Owner BEIJING ZHONGTAI TIANHE SCI & TECH
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