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Traditional Chinese medicinal micro-ecological composition, preparation thereof, and preparation method of preparation

A technology of traditional Chinese medicine microecology and composition, which is applied in the field of traditional Chinese medicine microecological preparations and their preparation, and traditional Chinese medicine microecological compositions, can solve the problems of uneven stirring, flatulence, blocked water lines, etc., and can shorten the dissolution time and bioavailability. The effect of high and improved absorption rate

Inactive Publication Date: 2015-01-21
HENAN UNIV OF ANIMAL HUSBANDRY & ECONOMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Liquids are subject to certain restrictions in terms of transportation and storage, and are prone to secondary fermentation, resulting in stink and other phenomena
However, the powder form is prone to flatulence, agglomeration, clogging of water lines, uneven mixing, etc.

Method used

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  • Traditional Chinese medicinal micro-ecological composition, preparation thereof, and preparation method of preparation
  • Traditional Chinese medicinal micro-ecological composition, preparation thereof, and preparation method of preparation

Examples

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Effect test

Embodiment 1

[0036] The traditional Chinese medicine micro-ecological composition in the present embodiment consists of the following components: Astragalus water extract 600mL, broth 300mL, corn flour 100g, (NH 4 ) 2 SO 4 0.02g, and the Bacillus subtilis bacterial classification of 1% of the inoculum amount; Wherein the broth is beef broth; The total amount of the Bacillus subtilis inoculation is 1×10 9 cfu / mL.

[0037] The traditional Chinese medicine microecological preparation in this example is composed of the following components: 50g of fermented concentrated extract of traditional Chinese medicine microecological composition, 40g of sodium bicarbonate, 32g of anhydrous citric acid, diluent: 98g of anhydrous glucose, 30g of soluble starch, paste Essence 10g, flavoring agent: stevia 2g.

[0038] The preparation method of Chinese medicine probiotics in the present embodiment comprises the following steps:

[0039] (1) Preparation of Astragalus water extract: Weigh clean Astragalus...

Embodiment 2

[0045] The traditional Chinese medicine micro-ecological composition in the present embodiment consists of the following components: Astragalus water extract 500mL, broth 200mL, corn flour 80g, (NH 4 ) 2 SO 4 0.01g, and 0.5% inoculum of Bacillus subtilis strains; the broth formula is: peptone 10g, beef extract 3g, sodium chloride 5g, water 1000mL, pH value 7.4, autoclaved at 121°C for 15min; Bacillus subtilis The total amount of bacilli inoculated was 1×10 9 cfu / mL.

[0046] The traditional Chinese medicine microecological preparation in this example is composed of the following components: 50 g of fermented and concentrated extract of traditional Chinese medicine microecological composition, 40 g of sodium bicarbonate, 36 g of anhydrous citric acid, diluent: 135 g of sucrose, and flavoring agent: Aspera Tan 2g.

[0047]The preparation method of Chinese medicine probiotics in the present embodiment comprises the following steps:

[0048] (1) Preparation of the fermented a...

Embodiment 3

[0053] The traditional Chinese medicine micro-ecological composition in the present embodiment is made up of the following components: Astragalus water extract 700mL, broth 400mL, corn flour 120g, (NH 4 ) 2 SO 4 0.03g, and the Bacillus subtilis bacterial classification of 1.5% inoculum; Wherein the broth is pork broth; The total inoculation amount of Bacillus subtilis is 1.50×10 9 cfu / mL.

[0054] The traditional Chinese medicine micro-ecological preparation in this embodiment is composed of the following components: 50 g of fermented and concentrated extract of traditional Chinese medicine micro-ecological composition, 36 g of sodium bicarbonate, 32 g of anhydrous citric acid, diluent: 118 g of soluble starch, 24 g of dextrin, and flavoring Ingredients: sodium saccharin 2g.

[0055] The preparation method of Chinese medicine probiotics in the present embodiment comprises the following steps:

[0056] (1) Preparation of the fermented and concentrated extract of the microec...

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Abstract

The invention discloses a traditional Chinese medicinal micro-ecological composition, a preparation thereof, and a preparation method of the preparation, and belongs to the technical field of biological pharmacy. The traditional Chinese medicinal micro-ecological composition is obtained by compounding a Radix Astragali extract with Bacillus subtilis, and aims to organically combine a traditional Chinese medicine with micro-ecology through the fermenting cultivation of the Bacillus subtilis by the Radix Astragali extract. The Bacillus subtilis can improve the feed utilization rate, improve the disease resistance of animals and increase the immunity of the animals, and Radix Astragali can strengthen the specific immunity (humoral immunity and cellular immunity) and the nonspecific immunity of bodies, and can significantly promote the antibody generation of the bodies. The Radix Astragali is used to ferment the Bacillus subtilis in order to effectively improve the effects of the traditional Chinese medicine, protect the active components of the traditional Chinese medicine from being destroyed and change the microbial metabolic pathway to form a new active component, so the composition and the preparation can be applied in the animal bodies to perform a synergistic effect in order to improve the productivity of the animals and the immunity of the bodies.

Description

technical field [0001] The invention relates to a traditional Chinese medicine microecological composition, and also relates to a traditional Chinese medicine microecological preparation and a preparation method thereof, belonging to the technical field of biopharmaceuticals. Background technique [0002] Bacillus subtilis is a kind of Bacillus genus, which belongs to Gram-positive bacteria, without capsule, with perinatal flagella, and can move. Bacillus subtilis can produce subtilisin, polymyxin, nystatin, gramicidin and other active substances during the growth process, which has obvious inhibitory effect on pathogenic bacteria or endogenous infection, and can also Rapid consumption of free oxygen in the environment creates a hypoxic environment in the intestines, promotes the growth of beneficial anaerobic bacteria, and produces organic acids to lower the pH value of the intestines, indirectly inhibits the growth of other pathogenic bacteria, stimulates the growth and de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A61K36/481A61K9/16A61K9/46A61P37/04A23K1/16A61K35/74C12R1/125
CPCA61K36/481A61K9/0007A61K9/1617A61K35/742A61K2236/19A61K2300/00
Inventor 乔宏兴王永芬胡晓波李骞边传周
Owner HENAN UNIV OF ANIMAL HUSBANDRY & ECONOMY
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