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Plateau royal jelly berry buccal tablet and preparation method thereof

A technology for royal jelly and berries, applied in the field of preparation of plateau royal jelly berry lozenges, can solve the problems of single product, no product developed, few active ingredients, etc., and achieve the effects of anti-oxidative aging, clearing damage and reducing depression.

Active Publication Date: 2015-04-29
GEERMU YUANXINTANG BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the utilization of royal jelly, seabuckthorn, black berry and Nitraria is mainly a single product in the market, and the main active substances of royal jelly, sea buckthorn, black berry and Nitraria—royal jelly 10-hydroxy-decenoic acid, seabuckthorn 5- The anthocyanins and total flavonoids in serotonin, Nitraria japonica and Lycium barbarum are fully utilized, and no products that are convenient for market circulation have been developed.
[0004] Chinese patent application 200710050063.8 compound seabuckthorn buccal tablet and its preparation method is by crushing bergamot into fine powder for later use, decocting seabuckthorn, Tibetan green fruit, Polygonatum odoratum with water, filtering, concentrating, drying, pulverizing, and finely mixing bergamot The powder is mixed, granulated, and compressed into buccal tablets. This patent application has the disadvantage of less raw materials for preparing the active ingredients of the product

Method used

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  • Plateau royal jelly berry buccal tablet and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Raw material pretreatment:

[0020] a. Royal jelly: quickly freeze the royal jelly at -10°C, then directly sublimate the ice crystals in the royal jelly under a vacuum condition with a pressure less than 4.6mmHg, and then crush it to make a dry powder;

[0021] b. Seabuckthorn: Seabuckthorn branches and peel residues are extracted with water, ion exchange, washing, elution, acid reduction, filtration, concentration, alcohol extraction, evaporation, drying, ethanol thermal dissolution, crystallization of hydrochloric acid ethanol solution, separation, and drying, that is Get seabuckthorn 5-hydroxytryptamine hydrochloride;

[0022] c. Nitraria: The extraction of Nitraria adopts two water extraction methods. For the first extraction, add 5 times of purified water, add 0.01% ascorbic acid and 0.05% citric acid, and extract after 10 minutes. Take out the extract, then add 5 times of water in the extraction tank, extract for the second time in the same way, combine the e...

Embodiment 2

[0029] (1) Raw material pretreatment:

[0030] a. Royal jelly: quickly freeze the royal jelly at -15°C, then directly sublimate the ice crystals in the royal jelly under a vacuum condition with a pressure less than 4.6mmHg, and then crush it to make a dry powder;

[0031] b. Seabuckthorn: Seabuckthorn branches and peel residues are extracted by water, ion exchange, washing, precipitation, acid reduction, filtration, concentration, alcohol extraction, evaporation, drying, ethanol thermal dissolution, crystallization of hydrochloric acid ethanol solution, separation, and drying. Sea buckthorn 5-hydroxytryptamine hydrochloride;

[0032] c. Nitraria: The extraction of Nitraria adopts two water leaching methods. For the first extraction, add 30 times of purified water, add 0.10% ascorbic acid and 0.10% citric acid, and extract for 50 minutes. Take out the extract, then add 20 times of water in the extraction tank, extract for the second time in the same way, combine the two extrac...

Embodiment 3

[0039] (1) Raw material pretreatment:

[0040] a. Royal jelly: Quickly freeze royal jelly at -12°C, then directly sublimate the ice crystals in royal jelly under vacuum conditions with a pressure less than 4.6mmHg, and then crush it to make dry powder;

[0041] b. Seabuckthorn: Seabuckthorn branches and peel residues are extracted with water, ion exchange, washing, elution, acid reduction, filtration, concentration, alcohol extraction, evaporation, drying, ethanol thermal dissolution, crystallization of hydrochloric acid ethanol solution, separation, and drying, that is Get seabuckthorn 5-hydroxytryptamine hydrochloride;

[0042]c. Nitraria: The extraction of Nitraria adopts two water leaching methods. For the first extraction, add 30 times of purified water, add 0.05% ascorbic acid and 0.10% citric acid, and extract after 30 minutes. Take out the extract, then add 10 times of water in the extraction tank, extract for the second time in the same way, combine the two extracts ...

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Abstract

The invention relates to a plateau royal jelly berry buccal tablet and a preparation method thereof. The product is prepared by extracting 10-hydroxy-2-decenoic acid, 5-hydroxytryptamine and procyanidine from royal jelly, seabuckthorn fruit, nitraria sibirica pall and lycium ruthenicum murr, granulating, drying, arranging granules and tabletting. The invention aims at providing a plateau royal jelly berry buccal tablet which is rich in 10-hydroxy-2-decenoic acid, 5-hydroxytryptamine and procyanidine; the buccal tablet has functions of promoting sleeping, relieving the occurrence of depression, resisting oxidation and delaying aging, and the buccal tablet is broad in market prospect.

Description

technical field [0001] The invention relates to the field of lozenge processing, in particular to a preparation method of plateau royal jelly berry lozenges. Background technique [0002] Freeze-dried royal jelly powder, with its flat nature, sweet and sour taste, enters the spleen, liver and kidney channels, nourishes blood and nourishes the liver, calms the mind and calms the nerves, and is the king drug; seabuckthorn extract calms the heart and calms the nerves, anti-depression is the minister drug, and The monarch medicine wants to be compatible, to help the monarch medicine soothe the nerves and relieve troubles; Nitraria and black fruit wolfberry are the envoys for nourishing the spleen and stomach. Royal jelly, seabuckthorn, white thorn and black wolfberry all have sedative and hypnotic ingredients. Royal jelly 10-hydroxy-decenoic acid, seabuckthorn 5-hydroxytryptamine, anthocyanins and total flavonoids in Nitraria japonica and Lycium barbarum are the main active ing...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L1/076A23L1/212A23P1/02A23L19/00A23L21/20A23L33/00
CPCA23V2002/00A23V2200/30A23V2250/21
Inventor 孙朝晖山永凯李树志任蓓蕾
Owner GEERMU YUANXINTANG BIOLOGICAL SCI & TECH
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