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Traditional Chinese medicine for treating spleen-deficiency and phlegm-damp type pediatric epilepsy, and preparation method thereof

A technology of traditional Chinese medicine for spleen deficiency and phlegm dampness, which is applied in the field of traditional Chinese medicine and its preparation for treating children with spleen deficiency and phlegm dampness. The effect of susceptibility to resistance

Inactive Publication Date: 2015-08-26
赵景岩
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although western medicine and western medicine have their advantages in controlling epileptic seizures, too strong inhibitory effect will cause damage to the brain nerve function and have obvious toxic side effects
Such as carbamazepine, epileptamine, etc., generally cannot completely cure epilepsy, and the side effects are large, drug dependence is easy to occur, and it is easy to cause side effects such as mental depression and mental retardation
In addition, often taking antiepileptic western medicine can easily lead to drug resistance. To maintain a certain curative effect, the dose must be increased, which will cause more serious damage.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0048] The present invention also provides the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine composition is granule, its preparation method comprises the following steps:

[0049] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use percolation to remove Slowly percolate at a speed of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, spray dry, spray dry The air inlet temperature of the machine is 160-175°C, and the outlet air temperature is 80-85°C, and then crushed into powder to make dry cream powder;

[0050] Step 2: adding 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin to the obtained dry paste powder t...

Embodiment 1

[0056] Example 1 Granules

[0057] Take 70g Acanthopanax, 240g Pine Knot, 110g Achyranthes bidentata, 200g Hazelnut, 280g Pu Songshi, 350g Ginger Tongcao, 330g Guanzhong, 130g Pearl Ginseng, 200g Tung Tung Root, 210g Beetroot vine, 200g Dew Honeycomb, water red 200g of flower seeds, 250g of rock cabbage, 200g of Wujia skin, 280g of Maima rattan, 300g of Du Heng, 50g of Phima grass root and 250g of August leaves.

[0058] Its preparation method comprises the following steps:

[0059] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 6 times that of the mixture and 90% ethanol, heat to boiling and reflux for 4 hours, filter, and use percolation method at a rate of 2ml per minute. Percolation, collecting the percolation liquid, then concentrating under reduced pressure at 0.08Mpa to a paste with a relative density of 1.08 at 55°C, spray drying, the inlet air temperature of the spray dryer is 170°C, and the outlet ...

Embodiment 2

[0061] Example 2 Capsules

[0062] Take 120g of Acanthopanax, 190g of Pine Knot, 140g of Achyranthes, 150g of Hazel, 330g of Pu Songshi, 300g of Tongcao, 380g of Guanzhong, 80g of Pearl Ginseng, 250g of Tung Tung Root, 160g of Beetroot vine, 250g of Dew Honeycomb, and water red 100g of flower seeds, 350g of rock cabbage, 150g of Wujia skin, 320g of Maima rattan, 250g of Du Heng, 100g of Phima grass root and 200g of August leaves.

[0063] Its preparation method comprises the following steps:

[0064] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% that is three times the mass of the mixture, heat and reflux for 1 hour, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 85% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extr...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating spleen-deficiency and phlegm-damp type pediatric epilepsy, and a preparation method thereof. The traditional Chinese medicine comprises the following raw material medicines: acanthopanax, loose knot, achyranthes aspera, Rungia pectinata, delavay fir seed, sensitive joint vetch wood, cyrtomium rhizome, Panax pseudo-ginseng Wsll. Var, tung tree root, rhombicleaf rhynchosia stem and leaf, nidus vespae, fructus polygoni orientalis, purple bergenia herb, cortex acanthopanacis, Gnetum montanum, wild ginger, root of Tali Falsehellebore and fiveleaf akebia fruit. The traditional Chinese medicine for treating spleen-deficiency and phlegm-damp type pediatric epilepsy has the beneficial effects that the traditional Chinese medicine provided by the invention has the advantages that medicine effect is exact, toxic or side effect is low, and children can take the medicine safely for a long time; damage to brain nervous function can be reduced; medicine tolerance is difficult to generate; and medicine dependence is reduced.

Description

technical field [0001] The invention relates to a medical preparation containing medicinal materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating children with spleen-deficiency and phlegm-dampness type epilepsy and a preparation method thereof. Background technique [0002] Epilepsy, commonly known as "shorn horn" or "epilepsy", is a chronic disease in which the sudden abnormal discharge of brain neurons leads to transient brain dysfunction. Due to the different starting sites and transmission modes of abnormal discharges, the clinical manifestations of epileptic seizures are complex and diverse, which can be manifested as paroxysmal motor, sensory, autonomic, conscious and mental disturbances. Epilepsy can occur in all age groups. The incidence of epilepsy in children is higher than that in adults, and the incidence of epilepsy decreases with age. In old age (after the age of 65), the incidence of epilepsy increas...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P25/08A61K35/64
Inventor 赵景岩
Owner 赵景岩