Preparation method of medical dressing

An electrospinning solution and the obtained technology are used in medical science, rayon manufacturing, bandages, etc., and can solve the problems of bacterial proliferation, easy infection, wound separation, and opacity.

Inactive Publication Date: 2015-08-26
NANYANG CITY CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after the adhesive layer absorbs a large amount of wound exudate, it often swells and even causes the wound to separate, and the body fluid it absorbs is not easy to evaporate, resulting in a large number of bacteria multiplying at the wound and prone to infection
Foaming polymer medical dressings have fast and powerful absorption capacity for exudate, but due to the strong absorption capacity, it may affect the self-cleaning process for low-level penetration wounds. In addition, foaming polymer medical dressings The dressing is opaque, making it difficult to observe the wound surface

Method used

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  • Preparation method of medical dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A preparation method of medical dressing, comprising the following steps:

[0025] Step 1, dissolve polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen with 80wt% ethanol aqueous solution to obtain the electrospinning solution primary material I, wherein polyvinyl acetate, methyl vinyl The weight ratio of ether-maleic anhydride copolymer to collagen is 3:2:4;

[0026] Step 2, dissolving polymethacrylic acid, acrylamide and N,N-methylenebisacrylamide with 68wt% formic acid aqueous solution to obtain the electrospinning solution primary material II, wherein polymethacrylic acid, acrylamide and N, The weight ratio of N-methylenebisacrylamide is 1:3:2;

[0027] Step 3, mix the primary electrospinning liquid material I obtained in step 1 with the primary electrospinning liquid material II obtained in step 2, add nano-clay, nano-silver, vitamin C, borax, ethylene glycol, mannose, and then stir the mixture After emulsification, the electrospinning s...

Embodiment 2

[0033] A preparation method of medical dressing, comprising the following steps:

[0034] Step 1, dissolve polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen with 80wt% ethanol aqueous solution to obtain the electrospinning solution primary material I, wherein polyvinyl acetate, methyl vinyl The weight ratio of ether-maleic anhydride copolymer to collagen is 6:4:8;

[0035] Step 2, dissolving polymethacrylic acid, acrylamide and N,N-methylenebisacrylamide with 68wt% formic acid aqueous solution to obtain the electrospinning solution primary material II, wherein polymethacrylic acid, acrylamide and N, The weight ratio of N-methylenebisacrylamide is 2:6:7;

[0036] Step 3, mix the primary electrospinning liquid material I obtained in step 1 with the primary electrospinning liquid material II obtained in step 2, add nano-clay, nano-silver, vitamin C, borax, ethylene glycol, mannose, and then stir the mixture After emulsification, the electrospinning s...

Embodiment 3

[0042] A preparation method of medical dressing, comprising the following steps:

[0043] Step 1, dissolve polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen with 80wt% ethanol aqueous solution to obtain the electrospinning solution primary material I, wherein polyvinyl acetate, methyl vinyl The weight ratio of ether-maleic anhydride copolymer to collagen is 6:4:9;

[0044] Step 2, dissolving polymethacrylic acid, acrylamide and N,N-methylenebisacrylamide with 68wt% formic acid aqueous solution to obtain the electrospinning solution primary material II, wherein polymethacrylic acid, acrylamide and N, The weight ratio of N-methylenebisacrylamide is 4:5:7;

[0045] Step 3, mix the primary electrospinning liquid material I obtained in step 1 with the primary electrospinning liquid material II obtained in step 2, add nano-clay, nano-silver, vitamin C, borax, ethylene glycol, mannose, and then stir the mixture After emulsification, the electrospinning sol...

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Abstract

The invention discloses a preparation method of medical dressing. The preparation method of medical dressing comprises the following steps: dissolving polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen with an ethanol aqueous solution to obtain an electrostatic spinning liquid primary material I; dissolving polymethylacrylic acid, acrylamide and N,N-methylene bisacrylamide with a formic acid aqueous solution to obtain an electrostatic spinning liquid primary material II; mixing the electrostatic spinning liquid primary material I and the electrostatic spinning liquid primary material II; adding nano-clay, nano-silver, vitamin C, borax, glycol and mannose; emulsifying after stirring; preparing a fibrous membrane by the obtained electrostatic spinning liquid by an electrostatic spinning method; and performing vacuum filtration and drying to obtain the medical dressing. The medical dressing can effectively sterilize and diminish inflammation and improve microcirculation of injured peripheral tissues, achieves the effects of easing pain, inhibiting bacterial reproduction and repairing wound, is safe to use and has no toxic or side effect on a human body.

Description

technical field [0001] The invention belongs to the technical field of medical dressings, and in particular relates to a preparation method of medical dressings. Background technique [0002] In daily life, people will damage the skin and produce wounds due to trauma, burns or surgery. In order to avoid external harmful microorganisms from infecting the wound and accelerate the healing of the wound, it is usually necessary to apply a medical dressing on the wound. A medical dressing is a wound dressing that is mainly used to cover sores, wounds or other damages to protect the wound, absorb secretions, reduce infection and promote healing. [0003] Traditional medical dressings are mainly made of gauze, cotton and other materials whose main function is to clean or protect the wound. This type of medical dressing can effectively protect the wound surface, has a strong ability to absorb exudate, and is low in cost, easy to obtain raw materials, and simple to make. reusabl...

Claims

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Application Information

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IPC IPC(8): A61L15/32A61L15/24A61L15/44D01F8/10D01F8/02D01F1/10D01D5/00
Inventor 傅兴琴
Owner NANYANG CITY CENT HOSPITAL
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