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Traditional Chinese medicine combined preparation for treating radiation esophagitis

A technology of radiation esophagitis and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine, can solve the problems that patients cannot persist in completing radiation therapy and have obvious side effects, and achieve the effects of protecting esophageal mucosa, no toxic side effects, and convenient purchase

Inactive Publication Date: 2015-10-14
张梅 +1
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  • Abstract
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AI Technical Summary

Problems solved by technology

The prevention and treatment of radiation esophagitis by western medicine is mainly based on symptomatic treatment such as analgesic and antispasmodic, antibacterial and anti-inflammatory, and protection of esophageal mucosa. Although some symptoms can be effectively relieved, the side effects are also obvious, which makes patients often unable to persist in completing radiation therapy.

Method used

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Embodiment Construction

[0023] From June 2010 to September 2013, our hospital admitted and treated 83 patients with central non-small cell lung cancer and 58 patients with esophageal cancer. The indications for radiotherapy were: pathological diagnosis; the first radical radiotherapy. 141 patients were randomly divided into a treatment group of 71 cases and a control group of 70 cases. The two groups of patients were comparable. The treatment group: given traditional Chinese medicine preparations; the control group: 2 lidocaine (5ml / branch), dexamethasone 3 (5mg / branch), gentamicin 6 (8 万u / branch) add in 500ml of 5% glucose and shake well, each oral 15~20ml, every day 3 times before two groups of patients take medicine, all use isotonic normal saline to gargle.

[0024] Acute radiation esophagitis was classified into grades 0-4 according to the RTOG toxicity standard. Grade 0: No change; Grade 1: Mild dysphagia or painful swallowing; Grade 2: Moderate dysphagia or painful swallowing; Grade 3: Seve...

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Abstract

The invention discloses a traditional Chinese medicine combined preparation for treating radiation esophagitis, which is composed of honeysuckles, mint, fructus forsythiae, radix ophiopogonis, bamboo leaves, liquorice, smoked plum, radix rehmanniae, pericarpium citri reticulatae, pseudo-ginseng powder, borneol and honey. The preparation has the effect that when a patient suffered from chest or head and neck malignant tumor receives radiotherapy, dose-limiting reactions, such as congestion, edema, erosion or inflammatory exudative change and even anabrosis, in mucous membrane of esophagus. The traditional Chinese medicine combined preparation can alleviate even cure these symptoms so that the radiotherapy on the patients can be completed with significant treatment effect. The preparation is prepared through a water-decoction extraction process so that the characteristic of original taste of a traditional Chinese medicine decoction and effective components are free from losing. In addition, the retention time of the decoction in mucous membrane of esophagus is prolonged, thereby improving clinical curative effects.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine combination preparation for treating radiation esophagitis, which belongs to the field of traditional Chinese medicine. Background technique: [0002] Radiation esophagitis is a dose-limiting reaction that occurs when patients with malignant tumors of the chest and head and neck receive radiation therapy. It is caused by hyperemia, edema, erosion or inflammatory exudative changes or even ulcers in the normal esophageal mucosa in the irradiation field. Basically, it is a disease characterized by co-infection. Clinically, it is often manifested as dysphagia accompanied by painful retrosternal foreign body sensation or burning sensation, which is aggravated after eating. or even discontinue treatment. The prevention and treatment of radiation esophagitis by Western medicine mainly focuses on symptomatic treatment such as analgesic and antispasmodic, antibacterial and anti-inflammatory, and protecti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P1/00A61K31/045A61K35/644
Inventor 张梅王新强
Owner 张梅
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