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Traditional Chinese medicine gel for treating stage-III pressure sore and preparing method of traditional Chinese medicine gel

A technology of gel and traditional Chinese medicine, applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of low active ingredients, slow healing, high risk, etc., and achieve effective activity High composition, good biocompatibility, and good stability

Inactive Publication Date: 2015-12-09
陈红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Surgical treatment is risky, with large openings, great pain for patients, high cost, and slow healing; the use of antibiotics is only effective for wound infection, but it affects the healing time of wounds and prolongs the pain of patients
However, the existing traditional Chinese medicines for the treatment of decubitus are mostly outdated dosage forms such as powders or ointments, and there are widespread problems of complex drug compatibility, extensive preparation technology, and unreasonable selection of substrates, resulting in low active ingredients, excessive dosage, and incomplete efficacy. Play and other shortcomings

Method used

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  • Traditional Chinese medicine gel for treating stage-III pressure sore and preparing method of traditional Chinese medicine gel
  • Traditional Chinese medicine gel for treating stage-III pressure sore and preparing method of traditional Chinese medicine gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Prescription for clear ointment: 15 parts of Tang Songcao, 28 parts of Dandelion, 15 parts of Red Eclipta, 9 parts of Jiulixiang, 22 parts of Bugudan, 20 parts of Centipede vine, 10 parts of Angelica dahurica;

[0076] Gel prescription (by weight percentage): Chinese medicine clear ointment 16%, carbomer 9401.3%, hydroxypropyl methylcellulose 40001.0%, triethanolamine 1.3%, glycerin 6.5%, laurocaprolactone 2.5%, spit Wen-80 2.5%, ethylparaben 0.4%, the balance is water;

[0077] The preparation method of the gel: take Jiulixiang and Pigudan, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, first elute with water, remove the impurities dissolved in the polar solvent, and use the water The eluate was discarded and not used; and then eluted with 80% ethanol to collect the ethanol eluate of Jiulixiang and Bogudan;

[0078] Crush tang pine grass, dandelion, red eclipta, centipeda, and angelica dahuri...

Embodiment 2

[0081] Prescription for clear ointment: 15 parts of Tang Songcao, 28 parts of Dandelion, 15 parts of Red Eclipta, 9 parts of Jiulixiang, 22 parts of Bugudan, 20 parts of Centipede vine, 10 parts of Angelica dahurica;

[0082] Gel prescription (by weight percentage): Chinese medicine clear ointment 12%, carbomer 9401.15%, hydroxypropyl methylcellulose 40001.0%, triethanolamine 1.1%, glycerin 5.5%, laurocaprolactone 2%, surface Active agent Tween-80 2.5%, butylparaben 0.3%, the balance is water;

[0083] The preparation method of the gel: take Jiulixiang and Pigudan, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, first elute with water, remove the impurities dissolved in the polar solvent, and use the water The eluate was discarded and not used; then eluted with 85% ethanol to collect the ethanol eluate of Jiulixiang and Biaogudan;

[0084] Crush tang pine grass, dandelion, red eclipta, centipeda, and ...

Embodiment 3

[0087] Prescription for clear ointment: 15 parts of Tang Songcao, 28 parts of Dandelion, 15 parts of Red Eclipta, 9 parts of Jiulixiang, 22 parts of Bugudan, 20 parts of Centipede vine, 10 parts of Angelica dahurica;

[0088] Gel prescription (by weight percentage): Traditional Chinese medicine clear paste 18%, carbomer 9401.8%, hydroxypropyl methylcellulose 40001.3%, triethanolamine 1.9%, moisturizing agent glycerin 7%, laurocaprolactone 3.0% , Tween-80 3.0%, ethylparaben 0.3%, and the balance is water;

[0089] The preparation method of the gel: take Jiulixiang and Pigudan, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, first elute with water, remove the impurities dissolved in the polar solvent, and use the water The eluate was discarded and not used; then eluted with 78% ethanol to collect the ethanol eluate of Jiulixiang and Biaogudan;

[0090] Crush tang pine grass, dandelion, red eclipta, cent...

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Abstract

The invention discloses traditional Chinese medicine gel for treating a stage-III pressure sore and a preparing method of the traditional Chinese medicine gel. The traditional Chinese medicine gel is prepared from 10-20% of traditional Chinese medicine clear paste, 0.5-3% of high polymer material, 0.5-3% of neutralizer, 6-8% of wetting agent, 2-5% of skin previous absorbent, 2-3.5% of surfactant, 0.2-0.8% of preservative and the balance water. The traditional Chinese medicine clear paste is prepared from thalictrum, dandelions, herba hyperici, camuning, buddleja asiatia, pothos repens and radix angelicae. The medicine is used in combination and has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, cooling the blood to relieve swelling, removing necrotic tissue and promoting granulation, growth and reproduction of infection pathogen can be effectively controlled, meanwhile, the microcirculation around a wound surface is improved, local blood flow is increased, skin channels are dredged, toxic materials are removed, necrotic tissue fades, swell is totally dispersed, and fresh meat automatically grows. Meanwhile, the obtained gel has good adhesion and a film forming characteristic, can be tightly attached to an action part for a long time and has good biocompatibility, the foreign body sensation is avoided after the gel is smeared, and clothes are not likely to be stained.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine gel for treating stage III pressure sores and a preparation method thereof. Background technique [0002] Pressure sores are also called decubitus ulcers or pressure ulcers. Due to the long-term pressure on the local tissues, the blood circulation is disturbed, and the tissues continue to be in a state of ischemia, hypoxia, and malnutrition, so that the skin gradually loses its normal physiological functions. tissue damage and necrosis. Traditional Chinese medicine calls pressure sores "bed sores". According to TCM theory, pressure sores are caused by long-term bed mats due to serious illnesses. The patient is under pressure for a long time and cannot turn to the side. The tendons and veins have been lost for a long time and cultivated by Confucianism. [0003] The current clinically generally accepted pressure ulcer stagin...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61K47/38A61K47/32A61K9/06A61P17/02
Inventor 孙言芳
Owner 陈红
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