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Gynecologic cleaning liquid with itch relieving effect, and preparation method thereof

A gynecological cleansing and antipruritic technology, which is applied to medical preparations containing active ingredients, inorganic non-active ingredients, pharmaceutical formulas, etc., can solve the problems of antipruritic, insignificant antibacterial effect, and large skin irritation, and achieve excellent relief Sterilization of itching and broad application prospects

Inactive Publication Date: 2016-05-11
GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems in the prior art that the cleansing liquid has great skin irritation and insignificant antipruritic and antibacterial effects, the present invention provides a gynecological cleansing liquid with antipruritic effect

Method used

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  • Gynecologic cleaning liquid with itch relieving effect, and preparation method thereof
  • Gynecologic cleaning liquid with itch relieving effect, and preparation method thereof
  • Gynecologic cleaning liquid with itch relieving effect, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1, the preparation method of the mixed extract of the present invention.

[0039] S1: Weigh 3 parts of Artemisia argyi leaves, 2 parts of Sophora flavescens, 2 parts of Angelica sinensis, 1 part of Motherwort and 2 parts of Moringa oleifera leaves. Measure 15 times the amount of ethanol solution with a volume fraction of 75%, adjust the carbon dioxide flow rate to 12L / h, extract the pressure at 12MPa, extract the temperature at 60°C, and extract for 5 hours, and separate under reduced pressure to obtain extract A, and keep the residue;

[0040] S2: add 3 times the amount of distilled water to the residue in S1 and decoct for 2 hours, filter and concentrate to obtain the first decoction;

[0041] S3: Combine the extract A and the first decoction to obtain the mixture extract.

Embodiment 2

[0042] Embodiment 2, the preparation method of Flos Japonica extract of the present invention.

[0043] S1: Weigh the mountain silver flower, wash it, dry it, crush it into coarse powder, add 0.5% pectinase of the total amount of the above coarse powder, and then add 10 times the amount of citric acid with a pH of 5.0 of the total amount of the coarse powder Buffer solution, enzymatic hydrolysis in a constant temperature water bath at 40°C for 4 hours;

[0044] S2: Raise the temperature to 80°C, keep the temperature constant for 15 minutes, add 50% ethanol solution with a volume fraction of 5 times the weight of the above coarse powder, reflux for extraction for 1 hour, filter with suction, and separate under reduced pressure to obtain the Jasmine Japonica extract.

Embodiment 3

[0045] Embodiment 3, the preparation method of Radix Paeoniae Alba extract of the present invention.

[0046] Take Radix Paeoniae Alba, wash, dry, crush, pass through a 100-mesh sieve, add 7 times the weight of Alba Paeoniae Alba coarse powder in ethanol with a volume fraction of 75%, soak for 8 hours, reflux extraction at 65°C for 2 times, 3 hours each time, filter , combined the filtrates, and concentrated the filtrate under reduced pressure to an extract with a relative density of 1.15 at 60° C., to obtain the Radix Paeoniae Alba extract.

[0047] Components (in parts by weight) of Examples 4-6 of the present invention and Comparative Examples 1-3 gynecological cleansing liquid

[0048]

[0049] The preparation method of the gynecology cleansing liquid with antipruritic effect of the present invention is:

[0050] S1: Weigh 3 parts of alkanolamide, 1.5 parts of alkyl polyglucoside, 0.5 part of essence and 60 parts of water, and stir until completely dissolved;

[0051]...

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Abstract

The invention belongs to the field of gynecologic detergents, and concretely relates to a gynecologic cleaning liquid with an itch relieving effect, and a preparation method thereof. The gynecologic cleaning liquid comprises, by weight, 2-6 parts of a nonionic surfactant, 15-45 parts of traditional Chinese medicine extract product, 0.5-1 part of an essence and 50-70 parts of water, and the traditional Chinese medicine extract product is prepared through mixing a mixed extract product, a white peony root extract product and a Wild Honeysuckle Flower extract product, and preparation raw materials of the mixed extract product comprise Artemisia argyi, Sophora flavescens, Chinese angelica root and Moringa tree leaf. The gynecologic cleaning liquid with an itch relieving effect, adopting the traditional Chinese medicine extract products as main active components, has the advantages of mildness, safety, no irritation, good stability, and substantial itch relieving and bacterium inhibiting effects.

Description

technical field [0001] The invention belongs to the field of gynecological detergents, and in particular relates to a gynecological cleaning liquid with an antipruritic effect and a preparation method thereof. Background technique [0002] Vaginal itching refers to the local itching of the vulva caused by factors such as daily inattention to hygiene, infection of inferior sanitary napkins, improper wearing, vaginitis or mental factors. There are various gynecological cleaning solutions on the market. , mainly divided into two categories: traditional Chinese medicine lotion and western medicine lotion, while western medicine lotion has a single effect, is prone to allergy, irritation, drug resistance, etc., and is not suitable for pregnant women and lactating women. [0003] Chinese patent application 201310133735.7 discloses a gynecological cleansing liquid and its preparation method, which is made of the following raw materials in parts by weight: Sophora flavescens, Cnidiu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/65A61K36/71A61P17/04A61P15/02
CPCA61K36/282A61K9/0034A61K9/08A61K36/185A61K36/232A61K36/355A61K36/489A61K36/533A61K36/65A61K36/71A61K47/02A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王一飞利奕成王巧利廖晓凤
Owner GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT