Unlock instant, AI-driven research and patent intelligence for your innovation.

Probiotics fermentation Liuwei Dihuang composition as well as preparation method and application thereof

A technology of Liuwei Dihuang and its composition, which is applied in the field of probiotic fermented Liuwei Dihuang composition and its preparation, can solve the problems that the efficacy of the medicine cannot be compared with that of western medicine, hinder the digestive function, and the side effects of the users, so as to shorten the taking cycle and reduce the Intestinal burden, the effect of optimizing the process

Inactive Publication Date: 2016-08-17
SANZHU FUER PHARMA
View PDF6 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparations included in the Pharmacopoeia are only the most primitive processing of medicinal materials. Although the newly developed preparations have further improved their efficacy, their efficacy is still not comparable to that of western medicines. exist
In addition, Liuwei Dihuang Wan is a medicine that tends to nourish yin, and there are more feminine medicines in the formula. After eating, it will hinder digestion, cause spleen and stomach weakness, and bring certain side effects to users

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Probiotics fermentation Liuwei Dihuang composition as well as preparation method and application thereof
  • Probiotics fermentation Liuwei Dihuang composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1: Preparation of Liuwei Dihuang Composition A by Probiotic Fermentation

[0031] The specific preparation method is as follows:

[0032] (1) Crushing: Grab according to the components of each Chinese medicine in the traditional Liuwei Dihuang prescription. The weight of each Chinese medicine in the prescription is: Rehmannia glutinosa 120g, Cornus cornus 60g, Moutan bark 45g, Chinese yam 60g, Poria cocos 45g, Alisma 45g, crushed and mixed, the fineness is 80 mesh.

[0033] (2) Extraction: Take the powder mixed in (1), add 10 times distilled water and soak for 60 minutes, add fructose 0.6% (weight g / volume ml), peptone 0.3% (weight g / volume ml), Yeast extract 0.1% (weight g / volume ml), yeast powder 0.06% (weight g / volume ml), inorganic salt (K 2 HPO 4 • 3H 2 O 0.1g / 100ml, KH 2 PO 4 0.1g / 100ml, FeSO 4 • 7H 2 O5.0mg / 100ml, ZnSO 4 • 7H 2 O 4.4mg / 100ml, MgSO 4 • 7H 2 O 25mg / 100ml), tagatose 3.0% (weight g / volume ml) and sucralose 0.005% (weight g / volume ml). Adjust pH t...

Embodiment 2

[0036] Example 2: Preparation of Liuwei Dihuang Composition B by Probiotic Fermentation

[0037] The specific preparation method is as follows:

[0038] (1) Crushing: Grab according to the components of each Chinese medicine in the traditional Liuwei Dihuang prescription. The weight of each Chinese medicine in the prescription is: Rehmannia glutinosa 120g, Cornus cornus 60g, Moutan bark 45g, Chinese yam 60g, Poria cocos 45g, Alisma 45g, crushed and mixed, the fineness is 70 mesh.

[0039] (2) Extraction: Take the powder mixed in (1), add 10 times distilled water and soak for 60 minutes, add fructose 0.5% (weight g / volume ml), peptone 0.2% (weight g / volume ml), Yeast extract 0.1% (weight g / volume ml), yeast powder 0.06% (weight g / volume ml), inorganic salt (K 2 HPO 4 • 3H 2 O 0.1g / 100ml, KH 2 PO 4 0.1g / 100ml, FeSO 4 • 7H 2 O5.0mg / 100ml, ZnSO 4 • 7H 2 O 4.4mg / 100ml, MgSO 4 • 7H 2 O 25mg / 100ml), tagatose 3.0% (weight g / volume ml) and sucralose 0.005% (weight g / volume ml), adjust the p...

Embodiment 3

[0042] Example 3: Preparation of Liuwei Dihuang Composition C by Probiotic Fermentation

[0043] The specific preparation method is as follows:

[0044] (1) Crushing: Grab according to the components of each Chinese medicine in the traditional Liuwei Dihuang prescription. The weight of each Chinese medicine in the prescription is: Rehmannia glutinosa 120g, Cornus pubescens 60g, Moutan cortex 45g, Chinese yam 60g, Poria cocos 45g, Alisma 45g, crushed and mixed, with a fineness of 60 mesh.

[0045] (2) Extraction: Take the powder mixed in (1), add 10 times distilled water and soak for 60 minutes, add fructose 0.4% (weight g / volume ml), peptone 0.3% (weight g / volume ml), Yeast extract 0.08% (weight g / volume ml), yeast powder 0.04% (weight g / volume ml), inorganic salt (K 2 HPO 4 • 3H 2 O 0.1g / 100ml, KH 2 PO 4 0.1g / 100ml, FeSO 4 • 7H 2 O 5.0mg / 100ml, ZnSO 4 • 7H 2 O 4.4mg / 100ml, MgSO 4 • 7H 2 O 25mg / 100ml), tagatose 3.0% (weight g / volume ml) and sucralose 0.005% (weight g / volume ml), ad...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a probiotics fermenttion Liuwei Dihuang composition and a preparation method thereof. The preparation method comprises the following steps: pulverizing all traditional Chinese medicines in a conventional Liuwei Dihuang preparation to obtain powder, putting the powder into water, adding fructose, glucose, peptone, yeast extract, yeast powder and a sweetening agent, then adding inorganic salt to obtain a mixture, performing sterilization, then continuously fermenting multiple strains of probiotics in batches, and adding prebiotics to obtain the probiotics fermenttion Liuwei Dihuang composition. The composition can be prepared into various Liuwei Dihuang preparations according to conventional methods. According to the probiotics fermenttion Liuwei Dihuang composition, the utilization rate of effective components of the raw materials is greatly increased; the multiple strains of probiotics are used for continuous fermentation in batches, so that the effective components of Liuwei Dihuang are changed into active substances easily absorbed by the intestinal tract, and the effect is enhanced. An experiment shows that the composition disclosed by the invention has the advantages of shortening the treatment period, reducing the side effects caused by stomach cold, fullness of the abdomen, loose stool and inappetence, and relieving the burden on the intestinal tract of a human body.

Description

Technical field [0001] The invention relates to a probiotic fermented Liuwei Dihuang composition and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Liuwei Dihuang Wan was originally derived from the "Jinkuishenqi Wan" (Guifu Dihuang Wan) in the famous work "Treatise on Febrile and Miscellaneous Diseases" by Zhang Zhongjing, the "medical sage". In the Northern Song Dynasty, the imperial physician Cheng Qian Yi believed that the kidney determines the growth and development of a person, and emphasized the theory that replenishing and reducing should be carried out at the same time. He then started with "Golden Chamber Kidney Qi Pills" and created a famous prescription for nourishing kidney yin-Liuwei Dihuang Pill, which is composed of six Chinese medicines including rehmannia, dogwood, yam, Alisma, Danpi, and Poria. [0003] According to statistics, in various literature reports, Liuwei Dihuang Wan treat...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P9/12A61P3/10A61P15/12A61P37/04A61P39/06
CPCA61K36/8945A61K36/076A61K36/40A61K36/65A61K36/71A61K36/804A61K36/884A61K2236/19A61K2300/00
Inventor 吴炳新陆继臣褚新红甄宗武孙筱林
Owner SANZHU FUER PHARMA