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Preoperative nursing gel for anorectal surgery and preparation method of gel

A gel technology for anorectal surgery, which is applied in the field of gel for preoperative care of anorectal surgery and its preparation, can solve problems affecting the effect of surgery, promote cell regeneration, relieve itching and discomfort, and enhance skin elasticity and moisturizing effect

Inactive Publication Date: 2016-09-28
葛秀萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, anorectal surgery usually requires enema treatment, and enema itself will increase the irritability of the perianal area, and patients with hypersensitivity will experience anal redness and swelling even before surgery, which will affect the surgical effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A gel for preoperative care of anorectal surgery, mainly composed of the following components by weight: 1% hydroxytyrosol, 2% glycosaminoglycan, 1% shikonin, 0.2% proanthocyanidin, olean Fruit glycosides 0.1%, ellagic acid 0.1%, gallic acid 0.2%, chitin 0.6%, seaweed gel 2.3%, basil essential oil 1%, eucalyptus oil 1.2%, surfactant, antibacterial preservative 0.1%, transdermal absorption Accelerator 0.01%, the rest is gel matrix.

[0022] Wherein, the glycosaminoglycan is preferably hyaluronic acid. The surfactant is any one of polyoxyethylene fatty acid ester, polyoxyethylene fatty alcohol ether, polyglycerol alkyl ether, glucose alkyl ether, polyoxyethylene alkyl ether or any combination of more than one. The antibacterial preservative is methyl hydroxybenzoate, and methyl hydroxybenzoate has a phenolic hydroxyl structure, so the antibacterial performance is stronger than benzoic acid and sorbic acid. The transdermal absorption enhancer is laurocaprazine. The gel ...

Embodiment 2

[0030] A gel for preoperative care of anorectal surgery, mainly composed of the following components by weight: 3% hydroxytyrosol, 4% glycosaminoglycan, 1.25% shikonin, 0.3% proanthocyanidin, olean Fruit glycosides 0.3%, ellagic acid 0.3%, gallic acid 0.25%, chitin 1.0%, alginate 2.9%, basil essential oil 1.25%, eucalyptus oil 1.6%, surfactant, antibacterial preservative 0.125%, transdermal absorption Accelerator 0.02%, the rest is gel matrix.

[0031] Wherein, the glycosaminoglycan is preferably hyaluronic acid. The surfactant is any one of polyoxyethylene fatty acid ester, polyoxyethylene fatty alcohol ether, polyglycerol alkyl ether, glucose alkyl ether, polyoxyethylene alkyl ether or any combination of more than one. The antibacterial preservative is methyl hydroxybenzoate, and methyl hydroxybenzoate has a phenolic hydroxyl structure, so the antibacterial performance is stronger than benzoic acid and sorbic acid. The transdermal absorption enhancer is laurocaprazine. Th...

Embodiment 3

[0039] A gel for preoperative care of anorectal surgery, mainly composed of the following components by weight: 5% hydroxytyrosol, 6% glycosaminoglycan, 1.5% shikonin, 0.4% proanthocyanidin, olean Fruit glycosides 0.5%, ellagic acid 0.5%, gallic acid 0.3%, chitin 1.4%, alginate 3.5%, basil essential oil 1.5%, eucalyptus oil 2.0%, surfactant, antibacterial preservative 0.15%, transdermal absorption Accelerator 0.03%, the rest is gel matrix.

[0040]Wherein, the glycosaminoglycan is preferably hyaluronic acid. The surfactant is any one of polyoxyethylene fatty acid ester, polyoxyethylene fatty alcohol ether, polyglycerol alkyl ether, glucose alkyl ether, polyoxyethylene alkyl ether or any combination of more than one. The antibacterial preservative is methyl hydroxybenzoate, and methyl hydroxybenzoate has a phenolic hydroxyl structure, so the antibacterial performance is stronger than benzoic acid and sorbic acid. The transdermal absorption enhancer is laurocaprazine. The gel...

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PUM

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Abstract

The invention discloses a preoperative nursing gel for an anorectal surgery and a preparation method of the gel. The preoperative nursing gel for the anorectal surgery mainly consists of the following components in parts by weight: 1-5% of hydroxytyrosol, 2-6% of glycosaminoglycan, 1-1.5% of alkannin, 0.2-0.4% of procyanidine, 0.1-0.5% of oleuropein, 0.1-0.5% of ellagic acid, 0.2-0.3% of gallic acid, 0.6-1.4% of chitin, 2.3-3.5% of a seaweed gel, 1-1.5% of basil essential oil, 1.2-2.0% of eucalyptus oil, a surfactant, 0.1-0.15% of an antimicrobial preservative, 0.01-0.03% of a transdermal absorption enhancer and the balance of a gel matrix. The preoperative nursing gel for the anorectal surgery disclosed by the invention is capable of effectively improving skin elasticity and gloss and relieving smooth muscle, and is capable of relieving skin allergy, reducing oxidative stress and taking a chemical protection effect on cells; and in addition, the gel can also activate the cells, promote new generation of the cells, improve nutrition state of the skin cells and rapidly relieve itching discomfort due to local nerve high sensitivity.

Description

technical field [0001] The invention relates to the technical field, in particular to a gel for preoperative care of anorectal surgery and a preparation method thereof. Background technique [0002] Anorectal surgery is a clinical discipline that treats tumors, trauma and other diseases that occur in the anus and large intestine with surgery as the main method. Anorectal diseases are most common in the anorectal segment. Drugs for anorectal diseases can only relieve symptoms when anorectal diseases occur, so most of them choose surgical treatment. Traditional anorectal surgery mainly includes anorectal resection and internal sphincterotomy. [0003] Postoperative care is currently the main focus of anorectal surgery care. However, after research and analysis and more and more evidence shows that the status of the perianal and anal ring during operation is closely related to the incidence and degree of postoperative complications. Since surgery itself is also a kind of ext...

Claims

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Application Information

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IPC IPC(8): A61K36/63A61K9/06A61P39/00A61P17/00A61K31/05A61K31/728A61K31/122A61K31/352A61K31/366A61K31/192A61K31/722A61K31/734
CPCA61K9/0014A61K9/06A61K31/05A61K31/122A61K31/192A61K31/352A61K31/366A61K31/722A61K31/728A61K31/734A61K36/53A61K36/61A61K36/63A61K47/22A61K47/26A61K2300/00
Inventor 葛秀萍
Owner 葛秀萍
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