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Medical suture and preparation method thereof

A technology of sutures and servings, applied in the field of medical materials, can solve the problems of bacteriostasis, degradability, and biocompatibility to be improved, and achieve the effects of excellent degradation and absorption performance, biocompatibility, and simple production process.

Inactive Publication Date: 2016-09-28
SUZHOU COSMETIC MATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although the existing medical sutures can meet the needs of actual use, their antibacterial properties, degradation performance and biocompatibility still need to be improved.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A medical suture, which contains the following components in parts by mass: 35 parts of polyglycolide, 3 parts of chitin, 2 parts of collagen fiber, 1 part of pigskin collagen, 0.5 part of sodium alginate, 0.3 part of glucose, anisaldehyde 0.5 parts, 0.1 parts of sodium polyacrylate, 0.1 parts of o-benzoylsulfonimide, 0.2 parts of nanocellulose, 0.1 parts of vinyl silicone oil, 0.1 parts of polytetrafluoroethylene, and 0.1 parts of glutaraldehyde.

[0019] A preparation method of medical suture, the steps of the preparation method are as follows:

[0020] The first step: polyglycolide, chitin, collagen fibers, pig skin collagen, sodium alginate, glucose, anisaldehyde, sodium polyacrylate, o-benzoylsulfonimide, nanocellulose, vinyl silicone oil , polytetrafluoroethylene, and glutaraldehyde were added to the mixer, and mixed for 15 minutes at a speed of 70r / min;

[0021] The second step: melting and drawing the mixed materials in the first step into silk threads with a d...

Embodiment 2

[0024] A medical suture, which contains the following components in parts by mass: 55 parts of polyglycolide, 16 parts of chitin, 13 parts of collagen fiber, 8 parts of pigskin collagen, 4.5 parts of sodium alginate, 1.5 parts of glucose, anisaldehyde 2.5 parts, 0.4 parts of sodium polyacrylate, 0.4 parts of o-benzoylsulfonimide, 0.8 parts of nanocellulose, 0.5 parts of vinyl silicone oil, 0.4 parts of polytetrafluoroethylene, and 0.4 parts of glutaraldehyde.

[0025] A preparation method of medical suture, the steps of the preparation method are as follows:

[0026] The first step: polyglycolide, chitin, collagen fibers, pig skin collagen, sodium alginate, glucose, anisaldehyde, sodium polyacrylate, o-benzoylsulfonimide, nanocellulose, vinyl silicone oil , polytetrafluoroethylene and glutaraldehyde were added to the mixer, and mixed for 25 minutes at a speed of 90r / min;

[0027] The second step: melt and draw the mixed material in the first step into a silk thread with a dia...

Embodiment 3

[0030] A medical suture, containing the following components in parts by mass: 50 parts of polyglycolide, 13 parts of chitin, 10 parts of collagen fiber, 7 parts of pigskin collagen, 3.5 parts of sodium alginate, 1.2 parts of glucose, anisaldehyde 2 parts, 0.3 parts of sodium polyacrylate, 0.3 parts of o-benzoylsulfonimide, 0.7 parts of nanocellulose, 0.4 parts of vinyl silicone oil, 0.3 parts of polytetrafluoroethylene, and 0.3 parts of glutaraldehyde.

[0031] A preparation method of medical suture, the steps of the preparation method are as follows:

[0032] The first step: polyglycolide, chitin, collagen fibers, pig skin collagen, sodium alginate, glucose, anisaldehyde, sodium polyacrylate, o-benzoylsulfonimide, nanocellulose, vinyl silicone oil , polytetrafluoroethylene and glutaraldehyde are added to the mixer, and mixed for 20 minutes at a speed of 80r / min;

[0033] The second step: melt and draw the mixed material in the first step into a silk thread with a diameter o...

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Abstract

The invention relates to a medical suture and a preparation method thereof. The medical suture consists of the following ingredients in parts by mass: 35-55 parts of polyglycollide, 3-16 parts of chitin, 2-13 parts of collagen fibers, 1-8 parts of pigskin collagen, 0.5-4.5 parts of sodium alginate, 0.3-1.5 parts of glucose, 0.5-2.5parts of anisaldehyde, 0.1-0.4 parts of sodium polyacrylate, 0.1-0.4 parts of saccharin, 0.2-0.8 parts of nano cellulose, 0.1-0.5 parts of vinyl silicon oil, 0.1-0.4 parts of polytetrafluoroethylene and 0.1-0.4 parts of glutaraldehyde. The medical suture provided by the invention is excellent in degradation and absorption properties as well as biocompatibility; meanwhile, the medical suture can develop a bacteriostatic effect for a long time; and the medical suture, after being used for stitching wound, is free from the generation of inflammations and is not easy to cause scars.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to a medical suture and a preparation method thereof. Background technique [0002] Medical suture is a kind of thread material used for human surgical suture. From the perspective of material development, its development history has experienced silk thread, catgut, chemical synthesis thread, and pure natural collagen suture; from the perspective of absorbability, Experienced non-absorbable suture and absorbable suture; from its physical form, it can be divided into monofilament and multifibril; according to the source of raw materials, it can be divided into natural suture (animal tendon suture, catgut, silk and cotton thread) and artificial sutures (nylon, polyethylene, polypropylene, PGA, stainless steel wire and metal tantalum wire); according to biodegradability, it can be divided into non-absorbable sutures (metal thread, cotton thread, polyester, polypropylene, etc...

Claims

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Application Information

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IPC IPC(8): A61L17/10A61L17/08A61L17/00
CPCA61L17/105A61L17/005A61L17/08A61L17/10A61L2300/30A61L2300/404
Inventor 金仲恩全春兰张帆
Owner SUZHOU COSMETIC MATERIALS
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