Hydrogel collagen dressing especially suitable for oily skins

A collagen and oily skin technology, applied in the field of collagen dressings and hydrogel collagen dressings, can solve the problems of unconcerned about the transdermal absorption speed of collagen, and achieve faster transdermal absorption speed, significantly improved, transdermal The effect of improving the absorption rate

Inactive Publication Date: 2016-10-05
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, the studies so far have only focused on the transdermal absorp

Method used

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  • Hydrogel collagen dressing especially suitable for oily skins

Examples

Experimental program
Comparison scheme
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Example Embodiment

[0045] Example 1. Hydrogel type collagen dressing 1 (0.05% intact macromolecular collagen + water + macromolecule polymer)

[0046] Ingredients: sodium hyaluronate 0.05% (macromolecule polymer), glycerin 8.0%, butylene glycol 5.0%, glycerol polyether-26 2.0%, tocopherol acetate 0.5%, intact macromolecular collagen 0.05%, benzene Oxyethanol 0.2%, ethylhexylglycerol 0.1%, triethanolamine 0.6%, making the total amount 100% water.

[0047] Process operation:

[0048] ① Pre-dissolve the complete macromolecular collagen with 0.05mol / L acetic acid, adjust the pH to 5.0-6.0 with 0.01mol / L sodium hydroxide solution after complete dissolution, and make the final concentration of the mother liquor 0.05%;

[0049] ②Add sodium hyaluronate into water and stir until fully swelled; then add glycerin, butylene glycol, and glycerol polyether-26 in sequence, stir until uniform under heating, then add quantitative collagen mother liquor, stir until uniform, at 80 Incubate for 30 minutes at -85℃;

[0050...

Example Embodiment

[0051] Example 2. Hydrogel type collagen dressing 2 (0.1% human-like collagen + water + macromolecular polymer)

[0052] Ingredients: sodium alginate 0.05%, pectin 0.2% (macromolecule polymer), glycerin 5.0%, butanediol 3.0%, betaine 2.0%, tocopherol acetate 0.5%, human-like collagen 0.1%, benzene Oxyethanol 0.2%, ethylhexyl glycerol 0.1%, triethanolamine 0.5%, making the total amount 100% water.

[0053] Process operation:

[0054] ① Add sodium alginate and pectin to water and stir until fully swelled; then add glycerin, butanediol, betaine, and human-like collagen in sequence, stir until uniform under heating, and keep at 80-85°C for 30 minutes;

[0055] ②After the heat preservation, the temperature is reduced to 40-45°C, and the tocopherol acetate, phenoxyethanol, and ethylhexylglycerol are added. After stirring, add the triethanolamine, stir until the temperature is uniform, and cool down.

Example Embodiment

[0056] Example 3. Hydrogel type collagen dressing 3 (0.5% gelatin + water + macromolecular polymer)

[0057] Ingredients: Xanthan gum 0.3%, cellulose 0.2% (macromolecule polymer), glycerin 8.0%, butanediol 5.0%, glycerol polyether-26 2.0%, tocopherol acetate 0.5%, gelatin 0.5%, benzene Oxyethanol 0.2%, ethylhexylglycerol 0.1%, triethanolamine 0.6%, making the total amount 100% water.

[0058] Process operation:

[0059] ① Add xanthan gum and cellulose to water and stir until fully swelled; then add glycerin, butylene glycol, glycerol polyether-26, and gelatin in sequence, stir until uniform under heating, and keep at 80-85℃ for 30min;

[0060] ②After the heat preservation, the temperature is reduced to 40-45°C, and the tocopherol acetate, phenoxyethanol, and ethylhexylglycerol are added. After stirring, add the triethanolamine, stir until the temperature is uniform, and cool down.

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Abstract

The invention relates to the field of medical/beauty equipment, in particular to a hydrogel collagen dressing which is especially suitable for oily skin. The collagen dressing of the present invention comprises water, collagen and macromolecular polymers distributed in the water. It can promote rapid transdermal absorption of collagen, so it is more suitable as a medical/cosmetic collagen dressing in the field of medical treatment or medical cosmetology.

Description

technical field [0001] The invention relates to a collagen dressing, in particular to a hydrogel collagen dressing, and belongs to the field of cosmetic / medical equipment. Background technique [0002] Collagen, also known as collagen, is an important protein component of connective tissue that supports and protects the body. It is also the most abundant structural protein in many vertebrates and invertebrates. It provides mechanical strength to bones, tendons, cartilage and skin. Collagen is one of the most abundant proteins in mammals, accounting for about 20%-30% of the total protein in the body, and mainly exists in skin, bones, tendons, soft tissues, etc. Among them, about 70%-80% of the skin extracellular matrix is ​​collagen. Collagen has good biocompatibility, so it can be used in medical or cosmetic fields. [0003] From the perspective of biological activity, it is desirable to use as complete and large molecular weight collagen molecules as possible in collagen ...

Claims

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Application Information

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IPC IPC(8): A61L15/32A61L15/28A61L15/42A61K8/73A61K8/65A61K8/02A61Q19/00
Inventor 范代娣马晓轩严建亚
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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