Super water absorbent medical hemostatic material and preparation technology thereof

A hemostatic material and a preparation process technology, applied in the field of medical materials, can solve the problems of unsatisfactory comprehensive properties such as absorption and exudation capacity, absorption rate, mechanical properties and adhesion performance, poor hemostatic effect, etc., and achieve good hemostatic effect and good effect. Good for recovery, fast effect

Inactive Publication Date: 2017-03-29
SUZHOU AIBOMAIER NEW MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are various types of hemostatic materials, such as powder, sponge, foam, film, flake, flat plate, plain woven mesh, non-woven fabric, etc. Among them, the spongy hemostatic material is the most clinically used. However, its comprehensive properties such as the ability to absorb exudate, absorption rate, mechanical properties, hemostasis speed, and adhesion to the tissue at the bleeding site are not ideal, and the hemostatic effect is not good.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A superabsorbent medical hemostatic material, comprising the following components in parts by weight: 28 parts of chitosan, 8 parts of cross-linked polyacrylic acid, 5 parts of starch acrylic acid graft copolymer, 3 parts of plant polysaccharide, 3 parts of deer melon polypeptide, cross-linked 4 parts of linked dextran gel, 5 parts of aluminum phosphate, 3 parts of coconut shell fiber, 1 part of bamboo powder, 2 parts of β-carotene, 1 part of vitamin E acetate, 0.5 parts of povidone iodine, trimethylol 2 parts of propane triglycidyl ether, 0.6 parts of propylene oxide, 1.2 parts of garnetine, 2.4 parts of humic acid, 3.6 parts of ordoside, 6 parts of ethyl benzyl ester, and 5 parts of azone.

[0021] The plant polysaccharide is a mixture of white dextrin and cellulose, and the weight ratio of the two is 3:1.

[0022] The preparation process of the superabsorbent medical hemostatic material comprises the following preparation steps:

[0023] Step 1) Add chitosan, cross-...

Embodiment 2

[0028] A superabsorbent medical hemostatic material, comprising the following components in parts by weight: 36 parts of chitosan, 14 parts of cross-linked polyacrylic acid, 10 parts of starch acrylic acid graft copolymer, 7 parts of plant polysaccharide, 6 parts of deer melon polypeptide, 9 parts of linked dextran gel, 11 parts of aluminum phosphate, 8 parts of coconut shell fiber, 4 parts of bamboo powder, 6 parts of β-carotene, 4 parts of vitamin E acetate, 2 parts of povidone iodine, trimethylol 5 parts of propane triglycidyl ether, 1.3 parts of propylene oxide, 3.5 parts of garnetine, 5 parts of humic acid, 5 parts of stenoside, 9 parts of ethyl benzyl ester, 10 parts of azone.

[0029] The plant polysaccharide is a mixture of locust bean gum, guar gum and pectin, and the weight ratio of the three is 4:2:1.

[0030] The preparation process of the superabsorbent medical hemostatic material comprises the following preparation steps:

[0031] Step 1) Add chitosan, cross-lin...

Embodiment 3

[0036] A superabsorbent medical hemostatic material, comprising the following components in parts by weight: 29 parts of chitosan, 10 parts of cross-linked polyacrylic acid, 6 parts of starch acrylic acid graft copolymer, 3.8 parts of plant polysaccharide, 3.5 parts of deer melon polypeptide, cross-linked 4.2 parts of linked dextran gel, 5.5 parts of aluminum phosphate, 3.6 parts of coconut shell fiber, 1.8 parts of bamboo powder, 2.4 parts of β-carotene, 1.8 parts of vitamin E acetate, 0.7 parts of povidone iodine, trimethylol 2.5 parts of propane triglycidyl ether, 0.8 parts of propylene oxide, 1.6 parts of garnetine, 2.8 parts of humic acid, 3.8 parts of ordoside, 6.5 parts of ethyl benzyl ester, and 6.2 parts of azone.

[0037] The plant polysaccharide is a mixture of white dextrin, locust bean gum and pectin, and the weight ratio of the three is 1:3:2.

[0038] The preparation process of the superabsorbent medical hemostatic material comprises the following preparation st...

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PUM

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Abstract

The invention discloses a super water absorbent medical hemostatic material and a preparation technology thereof. The hemostatic material comprises the following components: chitosan, crosslinked polyacrylic acid, starch acrylic acid graft copolymer, plant polysaccharide, cervus and cucumis polypeptide, sephadex gel, aluminum phosphate, coconut shell fiber, bamboo flour, beta-carotene, vitamin E acetate, povidone-iodine, trimethylolpropane triglycidyl ether, propylene oxide, granatenine, humic acid, saponins of colubrina asiatica, benzyl acetate, and azone. The provided medical hemostatic material has a good hemostatic effect, the hemostatic speed is quick, at the same time, the absorption rate is high, and the absorption amount is large, so the hemostatic material is very suitable for large and deep wounds and wounds with a large amount of bleeding, and at the same time, the hemostatic material promotes the healing of the wounds.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a superabsorbent medical hemostatic material and a preparation process thereof. Background technique [0002] Hemostasis is an important step in emergency medical treatment. Rapid hemostasis is required for patients undergoing surgical treatment and sudden trauma in daily life, especially for emergency treatment in prominent events. Rapid and effective hemostasis is crucial to the life of the patient. Safety is paramount. At present, there are various types of hemostatic materials, such as powder, sponge, foam, film, flake, flat plate, plain woven mesh, non-woven fabric, etc. Among them, the spongy hemostatic material is the most clinically used. However, its comprehensive properties such as its ability to absorb exudate, absorption rate, mechanical properties, hemostatic speed, and adhesion to the tissue at the bleeding site are not ideal, and the hemostat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/10A61L24/02A61L24/06A61L24/08
CPCA61L24/08A61L24/0005A61L24/001A61L24/0015A61L24/02A61L24/06A61L24/108A61L2300/112A61L2300/202A61L2300/30A61L2400/04C08L5/08C08L5/02C08L51/02C08L33/02
Inventor 李子寅花顺达
Owner SUZHOU AIBOMAIER NEW MATERIAL CO LTD
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