Cordyceps militaris granules and preparation method thereof

A technology of granule granules and Cordyceps militaris, which can be used in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. The problem of single product structure, etc., can improve the blood oxygen supply capacity, increase the utilization rate of raw materials, and increase the content of effective substances.

Inactive Publication Date: 2017-09-08
安徽阳光药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The current Cordyceps militaris granule products usually use superfine crushing technology to crush the fruiting bodies of Cordyceps militaris and then sell them directly as end products. The products are not highly targeted, have low added value, and have a single product structure, making it difficult to satisfy consumer groups. diverse needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of Cordyceps militaris granular granule, calculated according to weight percentage, is made of the following raw materials:

[0029] 35% cordycepin militaris extract, 35% cordyceps militaris polysaccharide extract, 10% astragalus polysaccharide extract, 10% maltodextrin, 7.7% fructose syrup, Beta-cyclodextrin at 2.22% and malic acid at 0.08%.

[0030] Cordyceps militaris polysaccharide extract is prepared by the following method:

[0031] 1) Raw material processing: crush the fruiting body of Cordyceps militaris, add ethanol with a volume concentration of 95% to the crushed raw material to extract by cold infiltration, initially separate the impurities of alcohol-soluble pigment in the form of filtrate, discard the filtrate, and filter the residue recovered and vacuum dried;

[0032] 2) Polysaccharide extraction: Mix the dried filter residue with 20% ethanol solution (the mass ratio of filter residue: ethanol solution is 1:10) for ultrasonic-assisted extraction...

Embodiment 2

[0043] A kind of Cordyceps militaris granular granule, calculated according to weight percentage, is made of the following raw materials:

[0044] 30% cordycepin militaris extract, 30% cordyceps militaris polysaccharide extract, 15% ganoderma polysaccharide extract, 15% maltodextrin, 6.5% fructose syrup, Beta-cyclodextrin at 3.4% and malic acid at 0.1%.

[0045] Cordyceps militaris polysaccharide extract is prepared by the following method:

[0046] 1) Raw material processing: crush the fruiting body of Cordyceps militaris, add ethanol with a volume concentration of 95% to the crushed raw material to extract by cold infiltration, initially separate the impurities of alcohol-soluble pigment in the form of filtrate, discard the filtrate, and filter the residue recovered and vacuum dried;

[0047] 2) Polysaccharide extraction: Mix the dried filter residue with 10% ethanol solution (the mass ratio of filter residue: ethanol solution is 1:20) for ultrasonic-assisted extraction, t...

Embodiment 3

[0058] A kind of Cordyceps militaris granular granule, calculated according to weight percentage, is made of the following raw materials:

[0059] 30% cordycepin militaris extract, 35% cordyceps militaris polysaccharide extract, 15% wolfberry polysaccharide extract, 10% maltodextrin, 6% fructose syrup, Beta-cyclodextrin at 3.95% and malic acid at 0.05%.

[0060] The preparation method of Cordyceps militaris granules:

[0061] 1) Mixing: Weigh and mix Cordycepin militaris extract, Cordyceps militaris polysaccharide extract, Lycium barbarum polysaccharide extract, maltodextrin, β-cyclodextrin, fructose syrup and malic acid according to the proportion, add appropriate amount of deionized Stir the water evenly to make it into a slurry to obtain a mixed slurry;

[0062] 2) Homogenization: The prepared mixed slurry enters the colloid mill, and then performs high-pressure homogenization in the homogenizer with a pressure of 40 MPa;

[0063] 3) Granulation: The homogenized slurry c...

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PUM

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Abstract

The invention provides cordyceps militaris granules and a preparation method thereof. The cordyceps militaris granules are prepared from cordycepin extract, cordyceps polysaccharide extract, ingredient polysaccharide extract, filler, a sweetening agent and a sour agent, wherein the ingredient polysaccharide extract is astragalus polysaccharide extract, lycium barbarum polysaccharide extract or ganoderma lucidum polysaccharide extract. The preparation method includes: 1) mixing, to be more specific, proportionally weighing the cordycepin extract, the cordyceps polysaccharide extract, the ingredient polysaccharide extract, the filler, the sweetening agent and the sour agent, mixing, adding an appropriate amount of deionized water, and well stirring to obtain mixed slurry; 2) homogenizing, to be more specific, adding the prepared mixed slurry into a colloid mill, and homogenizing in a homogenizer; 3) granulating, to be more specific, subjecting the homogenized slurry to granulation in a spray dryer. The cordyceps militaris granules have advantages that by adoption of ingredient polysaccharides for complementation of cordycepin, demands of consumer groups different in body conditions can be met while an immunity regulation efficacy is enhanced.

Description

technical field [0001] The invention belongs to the technical field of Cordyceps militaris health food, and in particular relates to a granule of Cordyceps militaris and a preparation method thereof. Background technique [0002] Cordyceps militaris is a precious Chinese herbal medicine, with a flat taste and sweet taste, which has the effects of nourishing the lungs and kidneys, stopping bleeding and resolving phlegm. Research results in recent years have shown that Cordyceps militaris is one of the important artificial substitutes of Cordyceps sinensis. It can reduce blood fat, prevent arteriosclerosis, protect heart and brain tissue, calm and hypnotize, enhance macrophage activity, anti-cancer, anti-inflammatory and antibacterial. , Anti-hypoxia and other aspects have good effects. The functional components and pharmacological effects of Cordyceps militaris are basically the same as those of natural Cordyceps sinensis, and its fruiting body is rich in important physiolog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L31/00A23L33/10A23L33/105A23L33/125A23P10/20A61K9/16A61K47/36A61K47/69A61K36/068A61P37/04A61K31/715
CPCA23L31/00A23L33/10A23L33/105A23L33/125A23P10/20A23V2002/00A61K9/0095A61K9/1652A61K31/715A61K36/068A23V2200/30A23V2200/324A23V2250/208A23V2250/21A23V2250/51A61K2300/00
Inventor 都剑
Owner 安徽阳光药业有限公司
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