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Preparation method of full-ingredient active ginseng extracting solution and lyophilized product

A technology of ginseng extraction and full ingredients, which is applied in the field of preparation of active ginseng extracts and freeze-dried products with full ingredients, can solve problems such as the inability to guarantee the content of active substances, achieve rapid absorption, relieve dryness, and high bioavailability Effect

Inactive Publication Date: 2017-10-20
李学龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The characteristics of the ginseng freeze-dried products reported above are all freeze-dried by fresh medicinal material slices, or freeze-dried after mixing fillers, disintegrants, lubricants, binders, and skeleton substances with ginseng extracts. The content level of all active substances in ginseng cannot be guaranteed, especially the content of rare ginseng saponins, volatile oil, biological enzymes, etc. These ingredients are the important active ingredients in fresh ginseng, so it involves the preparation method of active products with all ingredients of ginseng no report yet

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032](1) Wash 10kg fresh whole branches of ginseng (Panax ginseng C.A.Mey.) with sterile water, add 20kg of sterile water, and use a food shear to perform mechanical shearing at a shearing temperature of 4°C to break the ginseng cell wall The rate reaches 40%, which helps the ginseng tissue fluid to fully combine with the cell contents.

[0033] (2) Incubate the sheared ginseng tissue fluid and broken cells at 20-40°C for 24 hours, add to the stirring tank, start the stirrer, and stir at a speed of 60r / min to construct the biotransformation of ginseng with anaerobic endophytic bacteria - ginseng is good Oxygenous endophytic fungi biotransformation-compound transformation system of ginseng self-saponinase transformation:

[0034] a. Anaerobic endophytic bacteria biotransformation of ginseng: Turn on the vacuum pump of the stirring tank to keep the vacuum degree -0.08Mpa~-0.09Mpa, and carry out anaerobic biotransformation. The transformation temperature is 20°C, the stirring sp...

Embodiment 2

[0044] (1) Wash 10kg fresh whole branches of ginseng (Panax ginseng C.A.Mey.) with sterile water, add 50kg of sterile water, and use a food shear to perform mechanical shearing at a shearing temperature of 10°C to break the ginseng cell wall The rate reaches 80%, which helps the ginseng tissue fluid to fully combine with the cell contents.

[0045] (2) Incubate the sheared ginseng tissue fluid and broken cells at 20-40°C for 40 hours, add to the stirring tank, start the stirrer, and stir at a speed of 100r / min to construct the biotransformation of ginseng with anaerobic endophytic bacteria - ginseng is good Oxygenous endophytic fungi biotransformation-compound transformation system of ginseng self-saponinase transformation:

[0046] a. Anaerobic endophytic bacteria biotransformation of ginseng: Turn on the vacuum pump of the mixing tank to keep the vacuum degree -0.08Mpa~-0.09Mpa, and carry out anaerobic biotransformation. The transformation temperature is 30°C, the stirring s...

Embodiment 3

[0056] (1) Wash 10kg fresh whole branches of ginseng (Panax ginseng C.A.Mey.) with sterile water, add 30kg of sterile water, and use a food shear to perform mechanical shearing at a shearing temperature of 4°C to break the ginseng cell wall The rate reaches 60%, which is helpful for the full combination of ginseng tissue fluid and cell contents.

[0057] (2) Incubate the sheared ginseng tissue fluid and broken cells at 25-35°C for 30 hours, add to the stirring tank, start the stirrer, and stir at a speed of 80r / min to construct the biotransformation of ginseng with anaerobic endophytic bacteria - ginseng is good Oxygenous endophytic fungi biotransformation-compound transformation system of ginseng self-saponinase transformation:

[0058] a. Anaerobic endophytic bacteria biotransformation of ginseng: Turn on the vacuum pump of the stirring tank to keep the vacuum degree -0.08Mpa~-0.09Mpa, and carry out anaerobic biotransformation. The transformation temperature is 25°C, the sti...

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Abstract

The invention discloses a preparation method of a full-ingredient active ginseng lyophilized product. According to the method, a fresh ginseng is used as a main raw material; advanced technical measures such as a high-pressure bubble cleaning technology, a part-of-tissue shearing and wall breaking technology, a ginseng anaerobic endophytic bacteria bioconversion-ginseng aerobiotic endophytic fungi bioconversion-ginsenosidase conversion combined conversion technology, a centrifugal separation technology, an ultrasonic sterilization technology and a lyophilizing technology; compared with a conventional ginseng processing product preparation method such as drying, steaming and high-temperature extraction, the method has the advantages that the prepared full-ingredient active ginseng lyophilized product has the characteristics of complete retention of active ingredients of the ginseng, high rare ginsenosides content, rapid oral absorption, high biological utilization rate and the like. The product retains the cold and moistening nature of the ginseng; compared with dried and other ginseng processing products with relatively high dryness, the full-ingredient active ginseng lyophilized product has the distinct characteristic that the product is cold but not causing the dryness. A technical support can be provided for upgrading the ginseng industry in China.

Description

technical field [0001] The invention relates to a preparation method of a freeze-dried product containing nourishing and nourishing ingredients, and in particular provides a preparation method of a full-component active ginseng extract and a freeze-dried product. Background technique [0002] Ginseng is one of the most well-known varieties in the treasure house of traditional medicine in my country. It has been taken for more than 4,000 years. Its medicinal use was first recorded in "Shen Nong's Herbal Classic". effect. According to botanical classification, ginseng belongs to a genus in the family Araliaceae (Araliceae), including Panax ginseng C.A.Mey., Panax quinquefolium L., Panax notoginseng (Burk.) F.H. Chen) and other important varieties. Ginseng is sweet in taste and slightly bitter. It belongs to the spleen, lung, and heart meridians. It has the functions of invigorating vital energy, recovering the veins, nourishing the spleen and benefiting the lungs, promoting ...

Claims

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Application Information

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IPC IPC(8): A61K36/258
CPCA61K36/258A61K2236/15A61K2236/19A61K2236/331A61K2236/53
Inventor 李学龙
Owner 李学龙
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