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Traditional Chinese medicine composition for removing acne and application thereof

A composition and anti-acne technology, applied in the direction of drug combination, effective ingredients of hydroxyl compounds, pharmaceutical formulas, etc., can solve the problems that acne cannot be completely cured, pigmentation and scars are easy to occur, and reduce the weight of acne model animal rabbit ears , Reduce the hyperplasia index of rabbit ear tissue, and soften the hypertrophic scar

Inactive Publication Date: 2017-11-24
雷允上药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to provide a traditional Chinese medicine composition for removing acne and its preparation method for the above-mentioned deficiencies of current Propionibacterium acnes drug resistance, acne that cannot be completely cured, and often recurs after being cured and prone to pigmentation and scars.

Method used

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  • Traditional Chinese medicine composition for removing acne and application thereof
  • Traditional Chinese medicine composition for removing acne and application thereof
  • Traditional Chinese medicine composition for removing acne and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] 1. A Chinese medicine composition for removing acne, which is made from the following raw materials in parts by weight:

[0040] 40 parts of Centella asiatica extract, 10 parts of Scutellaria baicalensis extract, 20 parts of vitamin E, 20 parts of clove oil, 5 parts of licorice extract, 2 parts of Sophora flavescens extract, 5 parts of hydrolyzed pearl, 0.5 part of borneol.

[0041] 2, the preparation steps of Chinese medicine composition gel of the present invention

[0042] Take 3g of ethylparaben, add 90g of propylene glycol to dissolve, add 1800g of water, stir evenly, add 45g of carbomer, grind to make it completely swell, and set aside; take another 67.5g of triethanolamine, add 300g of water to dissolve, add while stirring Grind the above carbomer dispersion evenly to obtain a blank matrix and set aside; take another 40g of Centella asiatica extract, 10g of Scutellaria baicalensis extract, 20g of vitamin E, 20g of clove oil, 5g of licorice extract, 2g of Sophora ...

Embodiment 2

[0044] 1. A Chinese medicine composition for removing acne, which is made from the following raw materials in parts by weight:

[0045] Centella asiatica extract 30 parts, Scutellaria baicalensis extract 30 parts, vitamin E 10 parts, clove oil 15 parts, licorice extract 8 parts, flavescens extract 6 parts, hydrolyzed pearl 4 parts, borneol 2 parts.

[0046] 2. Accessories

[0047] 3, the preparation method of Chinese medicine composition cream of the present invention

[0048] The above-mentioned prescription Chinese medicine composition and auxiliary materials (40 parts of dimethyl sulfoxide; 160 parts of propylene glycol; 30 parts of triethanolamine; 30 parts of vitamin C; 180 parts of glyceryl monostearate; 220 parts of stearyl alcohol; 30 parts of beeswax; liquid wax 200 parts; 10 parts of paraben esters; 1200 parts of deionized water), mix evenly to obtain a cream, and the content of the traditional Chinese medicine composition is: 4.76%.

Embodiment 3

[0050] 1. A Chinese medicine composition for removing acne, which is made from the following raw materials in parts by weight:

[0051] Centella asiatica extract 25 parts, scutellaria baicalensis extract 20 parts, vitamin E 10 parts, clove oil 10 parts, licorice extract 7 parts, flavescens extract 5 parts, hydrolyzed pearl 2 parts, borneol 1 part.

[0052] 2, the preparation steps of Chinese medicine composition liniment of the present invention

[0053] (1) Add 600 parts of polyethylene glycol 800; 200 parts of triethanolamine; 200 parts of glycerin; 300 parts of deionized water into the reaction kettle, heat to 50°C, stir to mix and dissolve completely.

[0054] (2) Add prescription Chinese medicine composition (25 parts of Centella asiatica extract, 20 parts of Scutellaria baicalensis extract, 10 parts of vitamin E, 10 parts of clove oil, 7 parts of licorice extract, 5 parts of Sophora flavescens extract, 2 parts of hydrolyzed pearls, 1 part of borneol), 500 parts of ethan...

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Abstract

The invention discloses a traditional Chinese medicine composition for removing acne and an application thereof. The pharmaceutical composition comprises the following components: an extract product of Centella asiatica, an extract product of scutellaria roots, vitamin E, clove oil, an extract product of licorice, an extract product of flavescent sophora, hydrolyzed pearl, and borneol, and the materials and a proper amount of matrix are used for preparing a preparation for external use. The traditional Chinese medicine composition has efficacies for clearing heat and draining dampness, detoxifying, and dispersing the swelling; the composition has multiple efficacies for better inhibiting growth of Propionibacterium acnes without generation of drug resistance, resisting hyperplasia of scar, resisting chromatosis, resisting inflammation, easing pain, preserving moisture, adjusting balance of oil and fat, and the like; the product has obvious anti-acne effects, and can be used for thoroughly eradicating acne without recurrence after healing; the product does not have toxic and side-effects, and acne removal does not leave marks. Total effective rate of the traditional Chinese medicine composition for treating acne in four weeks is 100%, and acne of healed patients does not recur. After acne is treated, total effective rate for resisting chromatosis reaches 85.71%, the curative effects are better than the effects of Tretinoin cream, and obvious adverse reactions are not observed.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition or a cosmetic composition with acne-removing function and an application thereof. Background technique [0002] Acne is commonly known as whelk, pimples, dark sores, and in ancient Chinese medicine, it is called facial sores and wine thorns. It is a chronic inflammatory skin disease of the pilosebaceous unit, and its clinical manifestations are characterized by pleomorphic skin lesions such as acne, papules, pustules, nodules, and cysts that are prone to occur on the face. The condition of acne is protracted and stubborn. Some patients will leave erythema or pigmentation after the skin lesions subside, and it will take a long time to recover. Patients with more serious acne, such as pus marks, nodules, and cysts, tend to leave hyperplastic or hyperpigmentation after healing. Atrophic scars, if not treate...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61P17/10A61K8/98A61K8/9789A61K8/92A61K8/67A61K8/34A61Q19/00A61Q17/00A61K31/045A61K31/355A61K35/618
CPCA61K8/34A61K8/678A61K8/922A61K8/97A61K8/987A61K31/045A61K31/355A61K35/618A61K36/23A61K36/484A61K36/489A61K36/539A61K36/61A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2236/55A61Q17/005A61Q19/00A61K2300/00
Inventor 叶华王恒斌李全孙翔刘光曜罗年翠殷丽娜
Owner 雷允上药业集团有限公司
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