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Food capable of stopping vomiting

A food and antiemetic technology, applied in the field of functional food processing, can solve the problems of poor control of anticipatory vomiting and delayed emesis, poor effect of anticipatory vomiting, and unclear drug components, so as to increase the risk of tumor recurrence, No acute toxicity, no damage to liver and kidney function

Active Publication Date: 2018-01-05
四川荟生源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to avoid the increased risk of tumor recurrence due to discontinuation of chemotherapy drugs, reduce the mortality rate of cancer patients, and improve the survival rate and quality of life of cancer patients, the current mainstream drug for the treatment of CINV is the use of serotonin receptor antagonists (granisetron, tropane, etc.). Setron) and benzamides (metoclopramide), etc. for intravenous treatment, this type of drug has a strong and effective antiemetic effect on acute vomiting, but poor control of expected vomiting and delayed vomiting, and There are extrapyramidal system reactions, headache, dizziness, fatigue and other adverse reactions. The effective rate is not high when used alone, and it needs to be combined with other antiemetic drugs. Glucocorticoids represented by dexamethasone are almost Antiemetic drugs are an essential component of the emetic treatment regimen. The combination of antiemetic drugs can significantly improve the efficacy, but the mechanism of action is not yet clear. It may be achieved through anti-inflammatory or immunosuppressive effects, but patients with long-term medication will have moderate to severe adverse effects Reactions such as insomnia, high blood sugar, indigestion, anxiety, increased appetite, weight gain, acne, etc.
[0004] Traditional Chinese medicine has unique advantages in the treatment of CINV, especially compared with western medicine in the treatment of CINV, it has the advantages of relatively low price, less adverse reactions, and irreplaceable advantages; it is better for acute vomiting and delayed vomiting, but it is effective for anticipatory vomiting. Poor; common prescriptions include Dabanxia Decoction, Evodia Evodia Decoction, Xiaobanxia Fuling Decoction, Xiaochaihu Decoction, Jiangbanxia Decoction, etc. The application of traditional Chinese medicine preparations can not only reduce gastrointestinal reactions after chemotherapy, but also improve the general condition of patients and enhance their physical fitness. Enhance the tolerance of patients to chemotherapy, ensure that chemotherapy is completed on time, thereby improving the remission rate and quality of life, and prolonging the survival period. However, the disadvantages of traditional Chinese medicine preparations are: (1) There are various dosage forms and application time Long-term, unclear drug ingredients, causing allergic reactions, heart damage adverse reactions and other disadvantages; (2) Chinese medicine preparations take a long time to decoct, the amount is large, and the taste is bitter, which is not easy to be accepted by modern people; (3) The key to the effective use of Chinese medicine lies in Dialectical system, treatment fully embodies the principle of individualization, but this principle is not conducive to mass production, forming a market-oriented promotion and application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1, 5 parts of Codonopsis pilosula, 15 parts of Poria cocos, 10 parts of Zhuru, 10 parts of Huoxiang, 15 parts of ginger, 15 parts of mannose oligosaccharide, and 10 parts of Atractylodes macrocephala.

Embodiment 2

[0017] Example 2, 20 parts of Codonopsis pilosula, 20 parts of Poria cocos, 20 parts of Zhuru, 20 parts of Huoxiang, 20 parts of ginger, 20 parts of mannose oligosaccharide, and 15 parts of Atractylodes macrocephala.

Embodiment 3

[0018] Example 3, 15 parts of Codonopsis pilosula, 5 parts of Poria cocos, 15 parts of Zhuru, 10 parts of Huoxiang, 5 parts of ginger, 10 parts of mannose oligosaccharides, and 25 parts of Atractylodes macrocephala.

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PUM

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Abstract

The invention discloses a food capable of stopping vomiting. The food is made from the following raw materials in parts by weight: 5-20 parts of radix codonopsis, 5-20 parts of poria cocos, 5-20 partsof bamboo shavings, 5-20 parts of wrinkled gianthyssop herbs, 5-20 parts of ginger, 5-20 parts of oligomerization mannose and 5-25 parts of bighead atractylodes rhizomes. The food disclosed by the invention has the beneficial effects that side effects caused by serious vomiting produced due to CINV (chemotherapy-induced nausea and vomiting) during chemotherapy of cancer patients can be effectively reduced, the raw materials are compounded from medicinal and edible food materials and are scientific in measurement and reasonable in compatibility, and modernized production is utilized; and a modern biological extraction technique is used, formula materials are subjected to extraction to be made into a food which is easy to take, non-irritating to the stomach and convenient to carry, and thedisadvantages that a traditional Chinese medicine preparation is slow to take effect, long in decoction time, high in dosage, bitter in taste and not acceptable by modern people can be effectively overcome.

Description

technical field [0001] The invention relates to the field of functional food processing, in particular to an antiemetic food. Background technique [0002] Chemotherapy is one of the main ways to treat cancer, and it has obvious effects on the treatment of cancer patients. However, the side effects caused by chemotherapy, such as bone marrow suppression, liver and kidney function damage, and gastrointestinal reactions, among which chemotherapy-induced nausea and vomiting (Chemotherapy-induced nausea and vomiting) Nausea and vomiting (CINV) is the most common gastrointestinal reaction. The incidence of CINV in patients is 65%-85%. Its occurrence affects the quality of life of patients. In severe cases, it can cause water and electrolyte disorders and effective blood volume reduction. It even endangers the patient's life; at the same time, it also seriously affects the patient's treatment compliance, increases the psychological burden of the patient, and can even force the int...

Claims

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Application Information

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IPC IPC(8): A23L33/105A23L33/10A23L33/115A23L33/125A23L31/00A61K36/9068A61P1/08A61K31/702
Inventor 樊一春
Owner 四川荟生源生物科技有限公司
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