Fluorescent probe for detecting aluminum ions and zinc ions and preparation method and application

Abstract

The invention relates to a fluorescent probe for detecting aluminum ions and zinc ions, which is a helicene derivative. The fluorescent probe has no fluorescence itself, and is complexed with aluminumions or zinc ions, and then the corresponding fluorescence emission peak appears, so that the aluminum ions or zinc ions can be detected by utilizing fluorescence spectroscopy. The preparation methodcomprises the following steps: firstly, reacting methyl salicylate with hydrazine hydrate to form salicylhydrazide, and under the catalysis of piperidine, reacting the salicylhydrazide with an aldehyde group-containing heptadiene compound to generate a fluorescent probe compound I. The fluorescent probe I prepared by the invention has the advantages of simple and convenient synthesis, high yieldand easy preparation, and is suitable for enlargement synthesis and actual production applications. The fluorescent probe can detect the aluminum ions and the zinc ions by using a fluorescence method,and can be applied to the field of ion detection as a new probe. The probe has good molecule selectivity and high sensitivity, has the advantages of fast response and obvious advantages, and has a broad application prospect.

Description

【Technical field】 [0001] The invention belongs to the field of fluorescent probes for detecting metal ions, in particular to a fluorescent probe for selectively detecting aluminum ions and zinc ions, a preparation method and application thereof. 【Background technique】 [0002] Fluorescent probes can convert ion presence information into easily detectable optical signals, and then obtain the identification function of specific ions. The interaction with specific ions in the system will cause specific physical and chemical changes, resulting in changes in the corresponding optical signals. Fluorescent probes have many advantages such as high sensitivity and simplicity. [0003] Aluminum ion is a common metal ion, but it is not an essential element for the human body, and it is harmful to animals, plants and the environment. Excessive intake of aluminum ions by the human body cannot be quickly metabolized out of the body, which will cause damage to the central nervous system ...

AI Technical Summary

Problems solved by technology

3d due to zinc ions 10 4s 0 The electronic structure of Zn has no measurable spectrum and NMR signals, so commonly used detection methods such as ultraviolet spectroscopy, nuclear magnetic resonance, electron paramagnetic resonance, etc. are difficult to apply to the detection of zinc ions

Most of the existing zinc ion detection methods are based on fluorescent probe methods, but the detection process is easily interfered by cadmium ions

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