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Compound traditional Chinese medicine soft capsule used for treating rheumatism bone diseases, and preparation method thereof

A technology for compound traditional Chinese medicine and rheumatic bone disease, which is applied in the directions of capsule delivery, medical preparations containing active ingredients, antipyretics, etc., can solve problems such as the inability to effectively control the disease, and achieve long-term preservation and enhancement of functional properties. , the effect of changing the length of the course of treatment

Active Publication Date: 2018-01-26
武汉市元大生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, through clinical verification, the traditional Chinese medicine treatment method for rheumatic bone disease in the prior art can be cured except for a small number of patients, and most patients can only relieve symptoms and cannot effectively control the development of the disease.

Method used

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  • Compound traditional Chinese medicine soft capsule used for treating rheumatism bone diseases, and preparation method thereof
  • Compound traditional Chinese medicine soft capsule used for treating rheumatism bone diseases, and preparation method thereof
  • Compound traditional Chinese medicine soft capsule used for treating rheumatism bone diseases, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The present embodiment provides a kind of compound traditional Chinese medicine soft capsule for the treatment of rheumatic bone disease, and its preparation process is as follows:

[0043] First, weigh 200g Shichangpu, 100g tortoise shell, 150g Drynaria fortunei, 200g notopterygium, 200g Duhuo, 100g Caulis Spatholobus, 200g Chinese yam, 150g wolfberry, 150g astragalus, crush them through a 10-mesh sieve, add 10 times the amount of water, Decoct for 1 hour, filter with gauze to obtain the first extract; add 6 times the amount of water to the residue and decoct for 1 hour, filter to obtain the second extract, combine the two extracts and place them in a ceramic jar to cool; Add 50g honey and 100g brown sugar in the final extracting solution, stir well, obtain Chinese medicine extracting solution.

[0044] Then, inoculate the mixed bacterial solution of bifidobacterium, lactic acid bacteria and yeast into the above-mentioned traditional Chinese medicine extract, stir even...

Embodiment 2

[0049] This embodiment provides a compound traditional Chinese medicine soft capsule for treating rheumatism and bone disease, wherein the quality of the raw materials of the medicine is: 300g of Shichangpu, 50g of tortoise shell, 200g of drynaria, 150g of notopterygium, 150g of lovage, 50g of Caulis Spatholobus, 100g of Chinese yam, wolfberry 100g, astragalus 200g, honey 100g, brown sugar 50g, vitamin D 80g, grape seed oil 1000g.

[0050] The preparation method of the compound traditional Chinese medicine soft capsule for treating rheumatic bone disease in this example is the same as that in Example 1.

experiment example

[0052] 1. Materials and methods

[0053] 1.1 Experimental animals and environment: 60 SPF-grade female SD rats, weighing about 300 g; the experimental conditions were a barrier environment, during which the temperature of the experimental environment was 22-24°C and the humidity was 52-58%.

[0054] 1.2 Feed formula (%): low calcium casein 23.0, DL-methionine 0.3, corn starch 32.0, sucrose 30.0, fiber 5.0, corn oil 5.0, mixed mineral salt 3.5, mixed vitamin 1.0, choline bitartrate 0.2.

[0055] 1.3 Main instruments: SD-1000C bone mineral measuring instrument.

[0056] 1.4 Experimental method

[0057] 1.4.1 Ovariectomy: Rats were injected intraperitoneally with pentobarbital sodium solution at a dose of 30 mg / kg bw, bilateral ovariectomy was performed after anesthesia, and 20,000 units of penicillin was injected intramuscularly after the operation for 3 consecutive days; the sham operation group After opening the abdominal cavity, only about 0.5g of fat was removed, and the b...

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Abstract

The invention provides a compound traditional Chinese medicine soft capsule used for treating rheumatism bone diseases. The compound traditional Chinese medicine soft capsule used for treating rheumatism bone diseases comprises a soft capsule body and a soft capsule content; the soft capsule content comprises acorus tatarinowii, tortoise shell, Rhizoma Drynariae, notopterygium root, radix angelicae tuhuo, spatholobus stem, Chinese yam, Chinese wolfberry, Radix Astragali, honey, brown sugar, vitamin D, and grape seed oil. The invention also provides a preparation method of the compound traditional Chinese medicine soft capsule. The traditional Chinese medicine raw materials of the compound traditional Chinese medicine soft capsule are capable of tonifying liver and kidney at the same time,dispelling wind and eliminating dampness, relaxing tendons and activating collaterals, promoting blood circulation to remove blood stasis, and relieving swelling and pain, possesses obvious curative effect on rheumatism bone diseases, is high in cure rate, is safe and convenient; no toxic or side effect is caused; and problems in the prior art that rheumatism bone diseases treatment course is long, and cure rate is low are solved.

Description

technical field [0001] The invention belongs to the technical field of medicine and health care, and in particular relates to a compound traditional Chinese medicine soft capsule for treating rheumatic bone disease and a preparation method thereof. Background technique [0002] Rheumatic bone disease is mainly caused by wind-cold damp pathogens invading the human body and entering the meridians of the human body through the pores of the skin, causing blood circulation to be unsmooth. On the acupoints, if the acupoints of the whole body are severely blocked, shaking will occur, and the hands and feet will not be flexible. After a long period of time, the meridians will be blocked. In mild cases, it will cause unbearable pain, and in severe cases, it will be difficult to move, which will eventually lead to paralysis and disability. Traditional Chinese medicine believes that rheumatism bone disease belongs to the scope of "arthritis". Blocking qi and blood, causing qi and bloo...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/48A61P29/00A61K35/644A61K35/586A61K31/7016A61K31/59
Inventor 朱玲刘敏
Owner 武汉市元大生物科技有限公司