Compound Yinhuang composition injection for fever relieving, pain easing and inflammation preventing of animals

Abstract

The invention discloses a compound Yinhuang composition injection for fever relieving, pain easing and inflammation preventing of animals, and an application thereof, belongs to the field of veterinary drugs, and concretely relates to a medicinal composition containing honeysuckle flower extract (by chlorogenic acid), Radix Scutellariae extract (by baicalin) and metamizole sodium, and active components of the medicinal composition comprise, by weight, 1-10 parts of the honeysuckle flower extract (by chlorogenic acid), 1-100 parts of the Radix Scutellariae extract (by baicalin) and 10-1000 parts of the metamizole sodium. The dosage form of the medicinal composition can be any one of a solution type injection, a suspension type injection, an emulsion type injection and a sterile powder for injection. The compound Yinhuang composition injection has obvious synergistic effect and a remarkable treatment effect when used for the for fever relieving, pain easing and inflammation preventing ofanimals, and has the advantages of effective reduction of untoward effects of medicines, stable quality, high safety, simple preparation method, and suitableness for industrial production.

Description

technical field [0001] The invention relates to a compound Yinhuang composition injection for antipyretic, analgesic and anti-inflammation for animals and application thereof. It belongs to the field of veterinary medicine. Background technique [0002] With the rapid development of my country's intensive breeding industry and the continuous improvement of feeding and management levels, the incidence of various common diseases of livestock and poultry has decreased, while febrile diseases characterized by fever (including various acute infections in Western veterinary medicine) Diseases and infectious diseases) the incidence rate is on the rise, such as swine flu, blue ear disease, porcine streptococcal disease, avian influenza, mad cow disease, foot-and-mouth disease, schistosomiasis and other diseases seriously damage the healthy development of animal husbandry, resulting in the growth of livestock and poultry It is suppressed, and the production performance is reduced, whi...

AI Technical Summary

Problems solved by technology

However, the above dosage forms are inconvenient for veterinary use. Currently, the commonly used and convenient veterinary preparation dosage form is injection, which has high bioavailability and good effect.

However, because Analgin intramuscular injection is likely to cause a sudden drop in blood pressure, and the injection site is prone to redness, swelling, and pain, which can lead to local muscle atrophy and joint disorders, so the use of Analgin injection for humans has been gradually discontinued; for the convenience of veterinary use, consider In order to meet drug compliance and animal safety, it is necessary to solve the problem of serious adverse reactions caused by the injection of the pharmaceutical composition injection containing Sulpyrine

[0021] Patent CN102379920A discloses a veterinary antiviral antipyretic pharmaceutical composition, the prescription contains 1-6 parts of honeysuckle and 1-5 parts of analgin, and the dosage forms include injections and oral preparations, but the patent prescription does not contain Scutellaria baicalensis extract, The effect is not as good as the combination of the three, and the serious adverse reactions caused by the injection containing Analgin are not considered

[0022] Based on the above analysis, the traditional Chinese medicine ingredients honeysuckle extract (calculated as chlorogenic acid) and Scutellaria baicalensis extract (calculated as baicalin) are used in combination with Western medicine Analgin. The combination of Chinese and Western medicines has a synergistic effect and can quickly relieve Heat analgesic and anti-inflammatory, and the effect is long-lasting, which is better than the therapeutic effect of chemical medicine single prescription and pure Chinese medicine preparation, but the safety problem of pharmaceutical composition injection must be solved

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