A kind of equipment and method for producing lactobacillus

A technology of lactobacillus and lactic acid bacteria, applied in the directions of biochemical equipment and methods, microorganism-based methods, microorganisms, etc., can solve the problems of small production volume of finished products, cumbersome large-scale production, etc., to ensure freshness, improve final profits, The effect of reducing production energy consumption

Active Publication Date: 2021-03-02
呼伦贝尔康益药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no advanced and mature lactic acid bacteria manufacturing process in China, and large-scale production is cumbersome, and the amount of finished products produced by enterprises is small

Method used

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  • A kind of equipment and method for producing lactobacillus
  • A kind of equipment and method for producing lactobacillus
  • A kind of equipment and method for producing lactobacillus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Receiving, filtering, weighing, pre-sterilizing, separating, sterilizing, concentrating, fermenting, and spray drying of raw milk are general production areas, and strain activation culture, strain expansion culture, powder inoculation, and packaging are grade-D clean areas, with a temperature of 18 -26°C, relative humidity 20-65%.

[0085] 1. Preparation of concentrated milk

[0086] 1 filter, weigh

[0087] After the raw milk is filtered through the pipeline filter, it is pumped into the hanging electronic scale for weighing, and then enters the milk tank.

[0088] 2 pre-sterilized

[0089] The raw milk is pre-sterilized by a plate heat exchanger at 60-65°C, then cooled to below 10°C, and put into a 25T milk storage tank for storage.

[0090] 3 separated

[0091] Raw milk passes through a plate heat exchanger, heated to a temperature between 35-45°C, and starts the separator. When the rotation speed reaches 1500 rpm, the separation begins. The separated skim milk ...

Embodiment 2

[0146] 1. After the raw milk is filtered and weighed, a total of 52386kg of raw milk is received. At the same time, it is pre-sterilized at a temperature of 62°C and cooled at a temperature of 6°C, and put into a 25T milk storage tank.

[0147] 2. Raw milk is preheated by a plate heat exchanger at a temperature of 39°C-41°C, separated in an automatic separator at 1500 rpm, and the fat content is tested every hour to control it between 0.1%-0.2%.

[0148] 3. The skim milk is sterilized by a fully automatic straight tube sterilizing unit at a temperature of 130°C. 4. The skim milk is passed through an automatic double-effect falling-film evaporator, the first-effect temperature is 75°C-76°C, the second-effect evaporation temperature is 60°C, and the sterilization temperature is between 88°C-90°C to obtain concentrated milk. Detect the specific gravity of concentrated milk every hour, and control it at 1.06-1.07Be (Baume degree).

[0149] 5. The third-generation strains, fourth...

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Abstract

An equipment and method for producing lactic acid bacteria, the equipment includes a concentrated milk preparation device, a strain activation and expansion cultivation device, a fermentation device and a spray drying device, wherein the concentrated milk preparation device, the strain expansion cultivation device and the spray drying device are all It is connected to the fermentation device through pipelines. The method comprises the step of preparing concentrated milk culture medium, the step of strain activation and expanding culture and the step of fermentation. The production equipment of the present invention is advanced, and the technical process is simple, can save production cost, improve production efficiency, shorten production cycle, can form large-scale continuous production, and is suitable for enterprises to produce lactobacillus in large quantities.

Description

technical field [0001] The invention belongs to the field of biopharmaceuticals, in particular to a device and method for producing lactobacillus. Background technique [0002] At present, most of the medicines for the treatment of gastrointestinal diseases (enteritis, gastritis), dyspepsia, dysentery and other illnesses in China are mostly synthetic chemicals, which have certain toxicity and side effects. And the mixed taking of multiple medicines will produce toxic substances, which will damage human health. Such synthetic chemicals cannot be used as medicines for daily conditioning, maintenance of gastrointestinal function, and prevention of gastrointestinal diseases for a long time. [0003] Lactobacillus is a product of the fermentation and metabolism of Lactobacillus acidophilus in skim milk. It is a pure natural drug without any chemical components. It has the functions of helping digestion and treating gastrointestinal disorders, enteritis, gastritis, indigestion, d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/38C12M1/02C12P21/02C12R1/23
CPCC07K14/335C12M23/10C12M23/58C12M27/00C12M41/12C12M47/14
Inventor 郑熙亭田鲁江吴国民范景美马东玉沙洪鑫蔡宏娟张丽萍张晓梅
Owner 呼伦贝尔康益药业有限公司
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