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A kind of preparation method of micropill liquid-filled capsule with function of weight loss and health care

A technology of liquid-filled capsules and micro-pills, which is applied in the field of preparation of micro-pill liquid-filled capsules, can solve problems affecting health, metabolic disorders, and excessive concentrations of serum functional components, and achieve good roundness, easy operation, and effective protection Effect

Active Publication Date: 2020-06-23
BEIJING COMPETITOR SPORTS SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, after taking slimming capsules, the concentration of serum functional components will rise rapidly within a period of time, which may cause the concentration of serum functional components to exceed the standard. If this happens for a long time, it will cause the body's metabolism to be disordered and affect health problems.

Method used

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  • A kind of preparation method of micropill liquid-filled capsule with function of weight loss and health care
  • A kind of preparation method of micropill liquid-filled capsule with function of weight loss and health care
  • A kind of preparation method of micropill liquid-filled capsule with function of weight loss and health care

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] 1.1. Vitamin and mineral pellets: 1) Take blank starch pellet cores between 60 mesh and pour them into the fluidized bed, turn on the blower, heat the material so that the temperature of the material is preheated at 40°C, and the air flow is controlled at 2.5m 3 / m, the speed of the turntable is 600rpm, so that the fluidization of the blank ball core is uniform; 2) Turn on the peristaltic pump, control the microcrystalline cellulose flow rate to 50-100ml / min, add 300 grams of vitamins and minerals premixed through a 60 mesh sieve In the feed, the powder feeding rate is 25g / min, so that the pellets are enlarged until the powder is added. Continue to fluidize for 5 minutes, and dry at 400C to get it.

[0040] 1.2. Functional ingredient pellets

[0041] Mix 300 grams of L-carnitine tartrate, 25 grams of kelp extract, 25 grams of green tea extract, and 5 grams of microcrystalline cellulose, and add 50 grams of HPMC as a binder to prepare a soft material. 5cm strips; 2) ad...

Embodiment 2

[0045] 2.1. Vitamin and mineral pellets: 1) Mix 300 grams of vitamin and mineral powder and starch through 80 mesh evenly, add 2% polyvinylpyrrolidone solution to make soft material, pass through a 60 mesh sieve to obtain wet granules, place in In the shot blasting machine, adjust the blast frequency at 8-15HZ, the turntable frequency at 10-30HZ, and throw round for 3-5min. After the pellets with uniform size are formed, discharge the pellets and fluidize and dry them.

[0046] 2.2. Functional ingredient pellets

[0047] Mix 300 grams of L-carnitine tartrate, 25 grams of kelp extract, 25 grams of green tea extract, and 5 grams of microcrystalline cellulose, and add 50 grams of HPMC as a binder to prepare a soft material. 5cm strips; 2) adjust the rotating speed of the turntable at the bottom of the shot blasting machine, and use 85% ethanol solution as a wetting agent to make the strips fluidize and spheronize in the fluidized bed for about 8-10 minutes, dry, and properly siev...

Embodiment 3

[0052] 3.1. Vitamin and mineral pellets: 1) Pass 300 grams of vitamin and mineral premix through an 80-mesh sieve, mix evenly with 5 grams of microcrystalline cellulose, add an appropriate amount of purified water to make a soft material, and pass through a 20-mesh sieve Prepare wet pellets, put them in the shot blasting machine, adjust the blast frequency at 8-15HZ, turntable frequency at 10-30HZ, throw round for 3-5min, after forming pellets of uniform size, discharge, fluidized drying, Instantly. ;

[0053] 3.2. Functional ingredient pellets

[0054] 300 grams of L-carnitine tartrate, 30 grams of kelp extract, 30 grams of green tea extract, and 8 grams of microcrystalline cellulose are mixed evenly, and 50 grams of HPMC are added to prepare a soft material. 5cm strips; 2) adjust the rotating speed of the turntable at the bottom of the shot blasting machine, and use 85% ethanol solution as a wetting agent to make the strips fluidize and spheronize in the fluidized bed for ...

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Abstract

The invention relates to a preparation method for a liquid-filled pellet capsule with weight-reducing and health-care functions. The preparation method comprises the following steps: (1) vitamin-mineral pellets are prepared; (2) functional ingredient pellets are prepared; (3) pellet coating is prepared; (4) medium chain triglyceride and conjugated linoleic acid are dissolved by using water-solubleexcipient, so that mixture liquid 1 is obtained; (5) the mixture liquid 1 is mixed with silicon dioxide, glutin and water, so that mixture liquid 2 is obtained; (6) the prepared pellets are added with the mixture liquid 2 and an antioxidant and mixed, so that a liquid-filled capsule content is obtained; (7) a hollow capsule is filled with the liquid-filled capsule content. The pellets prepared bythe preparation method disclosed by the invention have the advantages of good roundness, moderate hardness and high yield. Moreover, the compound preparation obtained by the invention not only can prevent the interaction between medicines, but also can increase the stability of the preparation. The process of the method is simple and easy to operate.

Description

technical field [0001] The invention belongs to the technical field of preparations, and in particular relates to a preparation method of micropill liquid-filled capsules with functions of weight loss and health care. Background technique [0002] When most people lose weight, the absorption of vitamins and minerals is affected due to a single food intake or too little fat intake, resulting in a lack of vitamins and minerals in the body. Vitamins and minerals are trace nutrients needed by living organisms, but generally they cannot be produced by living organisms themselves, and need to be obtained through diet and other means. Vitamins and minerals cannot produce energy and form cells like carbohydrates, proteins and fats, but they regulate the metabolism of organisms. A deficiency of vitamins and minerals can lead to serious health problems, and adequate intake of vitamins and minerals can keep the body strong and healthy. Therefore, it is necessary to prepare a weight l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K45/06A61K36/82A61K9/48A61K9/50A61P3/04A61P3/02A61K31/205A61K36/03
CPCA61K9/5005A61K9/5084A61K31/205A61K36/03A61K36/82A61K45/06A61K2300/00
Inventor 李奇庚魏冰曹珍艳
Owner BEIJING COMPETITOR SPORTS SCI & TECH
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