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Rhinitis ointment containing periplaneta americana active component and preparation method

A technology of Periplaneta americana and active ingredients, which is applied in the field of external ointment containing Periplaneta americana and a variety of Chinese herbal medicines for the treatment of rhinitis and the preparation field, which can solve the problems of short-term treatment of rhinitis and large side effects, and achieve the repair of nasal mucosal lesions tissue, low recurrence rate, and no toxic side effects

Inactive Publication Date: 2018-06-15
云南宁康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The common symptoms of rhinitis include: acute rhinitis, chronic rhinitis, sinusitis, allergic rhinitis, drug-induced rhinitis, etc. Now the external medicines for treating rhinitis are generally sprays and ointments, but the external medicines for rhinitis on the market are generally chemical Synthetic, treats the symptoms but not the root cause. It only has a short-term therapeutic effect on rhinitis, and has many side effects. If you want to treat both the symptoms and the root causes, you need to combine Chinese and Western medicines. Only by treating the symptoms with Western medicine and treating the root cause with Chinese medicine can you fundamentally and effectively treat rhinitis

Method used

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  • Rhinitis ointment containing periplaneta americana active component and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] (1) The following mass percent components are prepared:

[0026] Periplaneta americana extract: 1%, Asarum extract: 1%, Peppermint essential oil: 0.1%, Patchouli extract: 0.2%, Aconite extract: 1%, Glycerin: 1%, Medical Vaseline: 2%, Glycerin Stearic acid: 1%, methyl p-hydroxybenzoate: 0.01%, deionized water: the balance; the sum of the above components is 100%;

[0027] The American cockroach extract adopts the alcohol submerged water extraction method, through the following operations:

[0028] A. Select the plump and firm Periplaneta americana adults, place them in a dryer and bake them at 65°C. After drying until completely dry, use ethanol as a solvent, according to the ratio of solid to liquid g / ml, 1:8, Soak it in ethanol with a concentration of 95v / v% for 2 months to obtain the mixture;

[0029] B. Filter the mixture, and use a small rotary evaporator to concentrate the obtained alcohol extract under reduced pressure to form an extract. The obtained extract is...

Embodiment 2

[0038] (1) The following mass percent components are prepared:

[0039] Periplaneta americana extract: 4%, Asarum extract: 1.5%, Peppermint essential oil: 0.4%, Patchouli extract: 0.4%, Aconite extract: 1.5%, Glycerin: 4%, Medical Vaseline: 7%, Glycerin Stearic acid: 4%, methyl p-hydroxybenzoate: 0.01%, deionized water: the balance; the sum of the above components is 100%;

[0040] The American cockroach extract adopts the alcohol submerged water extraction method, through the following operations:

[0041] A. Select the plump and firm Periplaneta americana adults, place them in a dryer and bake them at 60°C. After drying until completely dry, use ethanol as a solvent, according to the ratio of solid to liquid g / ml, 1:7, Soak it in ethanol with a concentration of 95v / v% for 2 months to obtain the mixture;

[0042] B. Filter the mixture, and use a small rotary evaporator to concentrate the obtained alcohol extract under reduced pressure to form an extract. The obtained extrac...

Embodiment 3

[0051] (1) The following mass percent components are prepared:

[0052] American cockroach extract: 6%, Asarum extract: 2%, Peppermint essential oil: 0.6%, Patchouli extract: 0.6%, Aconite extract: 2%, Glycerin: 6%, Medical Vaseline: 9%, Glycerin Stearic acid: 6%, methyl p-hydroxybenzoate: 0.02%, deionized water: the balance; the sum of the above components is 100%;

[0053] The American cockroach extract adopts the alcohol submerged water extraction method, through the following operations:

[0054] A. Select the plump and firm Periplaneta americana adults, place them in a dryer to bake at 75°C, and dry them until they are completely dry. Use ethanol as a solvent, and the ratio of solid to liquid is 1:9 in g / ml. Soak it in ethanol with a concentration of 95v / v% for 2 months to obtain the mixture;

[0055] B. Filter the mixture, and use a small rotary evaporator to concentrate the obtained alcohol extract under reduced pressure to form an extract. The obtained extract is lef...

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Abstract

The invention discloses rhinitis ointment containing a periplaneta americana active component and a preparation method. The rhinitis ointment is prepared from the following raw materials in percentageby mass: 1 to 20 percent of periplaneta americana extract, 1 to 8 percent of herba asari extract, 0.1 to 1 percent of herba menthae essential oil, 0.2 to 1 percent of herba pogostemonis extract, 1 to10 percent of radix aconiti carmichaeli extract, 1 to 10 percent of glycerol, 2 to 20 percent of medical vaseline, 1 to 10 percent of glyceryl stearate, 0.01 to 0.04 percent of methyl 4-hydroxybenzoate and the balance of de-ionized water. The rhinitis ointment disclosed by the invention has the effects of eliminating wind and dispelling cold, smoothening breathing, relieving swelling and pain andrepairing nasal mucosa lesion tissues; the rhinitis ointment has the advantages of simple composition and exquisite composition, is scientific and reasonable, has no toxic side effect and is convenient to use; rhinitis can be healed when the rhinitis ointment is used for one treatment course, and the rhinitis ointment has rapid curative effect, good curative effect, stable medical effect and lowrecurrence rate; the rhinitis ointment can be used for radically treating various nasal diseases including allergic rhinitis, acute rhinitis, chronic rhinitis, nasosinusitis and the like.

Description

technical field [0001] The invention relates to a rhinitis ointment for treating rhinitis, in particular to an external ointment containing Periplaneta americana and various Chinese herbal medicines for treating rhinitis and a preparation method thereof. Background technique [0002] Rhinitis is an inflammatory disease of the nasal cavity, which is the inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of nasal mucosa. The common symptoms of rhinitis include: acute rhinitis, chronic rhinitis, sinusitis, allergic rhinitis, drug-induced rhinitis, etc. Now the external medicines for treating rhinitis are generally sprays and ointments, but the external medicines for rhinitis on the market are generally chemical Synthetic, treats the symptoms but not the root cause, it only has...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61K9/06A61K47/14A61K47/10A61K47/06A61P11/02A61P37/08A61K35/64
CPCA61K47/06A61K47/10A61K47/14A61K9/0043A61K9/06A61K35/63A61K36/268A61K36/532A61K36/534A61K36/714A61K2236/333A61K2236/331A61K2300/00
Inventor 李映波农春秋孙笠雯赵思聪
Owner 云南宁康生物科技有限公司
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