A nano-sulfide near-infrared long afterglow material and its preparation and application

Abstract

The invention belongs to the technical field of near-infrared long afterglow nanomaterials and discloses a nano-sulfide near-infrared long afterglow material as well as preparation and application thereof. The nano-sulfide near-infrared long afterglow material is prepared from CaS as a base material by doping with 0.05-1.5 mol% of Tm<3+> or 0.05-1.5 mol% of Yb<3+>. The preparation method comprisessteps as follows: (1), a Tm(NO3)3 ethanol solution and / or a Yb(NO3)3 ethanol solution are / is mixed with a CaCl ethanol solution, and a mixed solution is obtained; (2), 1-thioglycerol is added to a Na2S ethanol solution, then the Na2S ethanol solution is subjected to a reaction with the mixed solution, an activating agent is added dropwise, a mixture is stirred continuously, left to stand, centrifuged, washed, dried, ground and subjected to heat treatment in inert atmosphere, and a product is obtained. The material is nanoscale and has good dispersity, afterglow decay time is as long as ten minutes, and the material is used as a near-infrared optical bioimaging fluorescence indicator; the method is simple, and cost is low.

Description

technical field [0001] The invention belongs to the technical field of near-infrared long afterglow materials, in particular to a rare earth ion (Yb 3+ and / or Tm 3 + ) activated nano-sulfide near-infrared long afterglow material and its preparation method and application. Background technique [0002] Optical imaging, using photons as an information source, represents a rapidly expanding field with direct applications in pharmacology, molecular cell biology, and diagnostics. However, this technique still has many limitations, especially the tissue autofluorescence produced by in vivo illumination and the weak tissue permeability under short-wave excitation light irradiation. In order to overcome these difficulties, scientists have studied a series of inorganic light-emitting materials, which emit light in the near-infrared region (NIR). Molecules emit near-infrared light (650-1350nm), which can be used for the detection of living molecular targets, because biological bloo...

AI Technical Summary

Problems solved by technology

The recently developed near-infrared long afterglow materials are often powder materials sintered at high temperature in solid phase, and high temperature sintering often leads to large particle size of long afterglow materials.

Although there are also a few long-lasting materials that can be prepared into nano-scale, they also encounter the problem of expensive raw materials, which is not conducive to the promotion of production

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