Anti-ultraviolet radix ginseng hairy root skin moisturizer and preparation method thereof
An anti-ultraviolet, skin-care lotion technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve problems such as adverse reactions, and the anti-ultraviolet effect of ginseng hair roots has not yet been found.
Inactive Publication Date: 2018-07-27
JILIN AGRICULTURAL UNIV
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Problems solved by technology
Ginseng has skin care, anti-ultraviolet, antibacterial and anti-inflammatory effects. In recent years, cosmetics with active ingredients of ginseng have gradually increased and achieved good results. However, adverse reactions often occur due to pesticide residues and heavy metal residues in ginseng.
Research on ginseng hairy roots mostly focuses on hairy root induction, optimization of culture conditions, and production of secondary metabolites, but no research on the anti-ultraviolet effect of ginseng hairy roots has been found
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Embodiment 1
[0010] Example 1 An anti-ultraviolet ginseng hair root skin care lotion and its preparation method
[0011] 1 Experimental materials and instruments
[0012] 1.1 Experimental materials
[0013] The hairy roots of ginseng were induced and subcultured by the present inventors. The ginseng is a 4-year-old ginseng. Kit Glutathione (GDH-Px), Catalase (CAT), Total Superoxide Dismutase (SOD), Malondialdehyde (MDA), Hydroxyproline (HYP), Interleukin 6 ( IL-6), tumor necrosis factor a (TNF-a), total protein quantitative determination (BCA) were purchased from Nanjing Jiancheng Co., Ltd.; phosphate buffer PBS was purchased from Biyuntian Biotechnology Company, matrix metalloproteinase-1 (MMP) -1), the matrix metalloproteinase-3 (MMP-3) kit was purchased from ABCAM company. Nitrocellulose membrane PVDF was purchased from Millipore, USA. Carbomer, propylene glycol, glycerin and ethanol were purchased from Tianjin Chemical Plant.
[0014] 1.2 Experimental equipment
[0015] UVB tube (Nanjing Hu...
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The invention relates to an anti-ultraviolet radix ginseng hairy root skin moisturizer and a preparation method thereof. The preparation method comprises the following specific steps: (1) a preparation method of a radix ginseng hairy root skin moisturizer base material: adding 5ml of glycerol and 5ml of propylene glycol into 90ml of de-ionized water and uniformly stirring; then adding 0.1g of sodium hyaluronate and uniformly mixing; slowly adding 0.1g of carbomer under high-speed stirring and regulating the pH (Potential of Hydrogen) value to be 7.0 by utilizing 10 percent sodium hydroxide soas to obtain the skin moisturizer base material; (2) a preparation method of the radix ginseng hairy root skin moisturizer: taking a radix ginseng hairy root dried product and 70 percent ethanol of which is 10 times the amount of radix ginseng hairy root dried product and uniformly mixing; carrying out ultrasonic extraction treatment for 108min; centrifuging and taking supernatant; volatilizing toobtain radix ginseng hairy root extract; adding the radix ginseng hairy root extract into the skin moisturizer base material obtained by step (1) according to the final concentration of the radix ginseng hairy root extract of 2 to 50mg / ml; uniformly mixing to prepare the radix ginseng hairy root skin moisturizer. The radix ginseng hairy root skin moisturizer provided by the invention has a very good anti-ultraviolet function.
Description
Technical field [0001] The invention relates to an anti-ultraviolet ginseng hair root skin care lotion and a preparation method thereof, belonging to the technical field of medicine, health and daily chemicals. Background technique [0002] Skin cancer is a malignant tumor that occurs in the skin, which can be divided into three categories: basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and melanoma (melanoma), of which more than 100,000 cases of malignant melanoma (MM) occur every year The mortality rate is extremely high. It can be seen that skin cancer is a major disease threatening human life, and it is of great significance to develop highly effective anti-skin cancer drugs. Ultraviolet radiation is one of the important factors for skin cancer. With the destruction of the ozone layer, more and more ultraviolet rays reach the ground. Studies have shown that long-term exposure of the human body to ultraviolet light, especially medium-wave ultraviolet rays, can caus...
Claims
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IPC IPC(8): A61K8/9789A61K8/81A61K8/73A61K8/34A61Q17/04A61Q19/00
CPCA61K8/9789A61K8/345A61K8/735A61K8/8147A61K2800/782A61Q17/04A61Q19/004
Inventor 臧埔郜玉钢赵岩祝洪艳何忠梅王立岩王璐张连学
Owner JILIN AGRICULTURAL UNIV