Compound preparation for increasing ratio of AKK (akkermansia muciniphila) bacteria and pathogenic bacteria in intestines as well as preparation method and application thereof

Abstract

The invention provides a compound preparation for increasing ratio of AKK (akkermansia muciniphila) bacteria and pathogenic bacteria in intestines as well as a preparation method and application thereof, and relates to the field of oral preparations. The compound preparation for increasing the ratio of AKK bacteria to pathogenic bacteria in the intestines is prepared from the following raw materials in percentage by mass: 21% to 64% of oligosaccharide, 21% to 44% of plant extract, 9% to 31% of fungus extract, 0.5% to 5% of sodium taurate, and 0.5% to 5% of elaeagnus angustifolia extract. The compound preparation has the advantages that the safety is good, and the intestinal flora can be effectively regulated. The preparation method of the compound preparation comprises the following stepsof mixing the oligosaccharide, the plant extract, the fungus extract, sodium taurate and the elaeagnus angustifolia extract, and grinding, so as to obtain the compound preparation. The preparation method has the advantages that the technology is simple, and the industrialized production is easy. The application of the compound preparation for increasing the ratio of AKK bacteria to pathogenic bacteria in the intestines is characterized in that the compound preparation is used for preparing the oral preparation for increasing the abundance of the AKK bacteria in the intestines, and reducing theabundance of the pathogenic bacteria.

Description

technical field [0001] The invention relates to the field of oral preparations, and in particular to a compound preparation for increasing the ratio of AKK bacteria / pathogenic bacteria in the intestinal tract, a preparation method and an application. Background technique [0002] Studies have shown that changes in the intestinal flora in the human body can lead to obesity. The mechanism is: high-calorie food enters the intestinal tract after being chewed by the teeth and initially degraded by the stomach, and the microorganisms living in the intestinal tract are responsible for the remaining digestion Work; during the fermentation process of microorganisms, a large amount of acetate will be produced, and these acetates will be absorbed by the intestines, pass through the blood-brain barrier with the blood circulation, and enter the brain; the acetates entering the brain will activate the parasympathetic nervous system . The parasympathetic nerve activated by acetate will se...

AI Technical Summary

Problems solved by technology

[0003] In addition, long-term intake of high-fat foods will lead to intestinal flora imbalance, resulting in higher levels of acetic acid in the intestines. This positive regulatory mechanism makes food intake larger and larger, thereby promoting obesity and insulin resistance.

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