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Fat reducing application of taro leaf polysaccharide

A technology of bean taro and polysaccharides, which is applied in the field of medicine, can solve the problems that the weight loss activity of bean taro leaf polysaccharides is rarely reported, and achieve significant weight loss and fat-lowering effects, good development prospects, and the effect of reducing triglyceride and total cholesterol content

Inactive Publication Date: 2018-10-02
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, many nutrition and health food researchers are currently paying close attention to the research and topics related to the occurrence and prevention of obesity and chronic diseases, but there are few reports on the weight loss activity of bean taro leaf polysaccharides

Method used

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  • Fat reducing application of taro leaf polysaccharide
  • Fat reducing application of taro leaf polysaccharide
  • Fat reducing application of taro leaf polysaccharide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1, the weight loss application of bean taro leaf polysaccharide, such as Figure 1-Figure 5 It has been shown that taro leaf polysaccharide has a significant weight-loss and lipid-lowering effect. The specific preparation steps of bean taro leaf polysaccharide are as follows:

[0049] (1), preparation of bean taro leaf polysaccharide crude product:

[0050] (1.1), according to the solid-liquid ratio of 1g:10ml, weigh 100g of taro leaves and add 1000mL of distilled water, extract in 80°C water bath for 4h (enzyme inactivation is also achieved during extraction), then beat, and then centrifuge (4000r / min centrifuge 30min), the supernatant obtained by centrifugation was suction filtered and the filtrate was collected;

[0051] (1.2), replace the bean taro leaves in step (1.1) with the centrifuged filter residue obtained in step (1.1), repeat the extraction 2 times, combine the filtrate three times and concentrate by rotary evaporation until it is 1 / 5 of the or...

Embodiment 2

[0067] Embodiment 2, the influence of bean taro leaf polysaccharide on fat, liver and other organ indexes of obese mice;

[0068] Fasted for 24 hours after 12 weeks of intragastric administration in Example 1, weighed the body weight, and killed the mice by cervical dislocation after blood was taken from the orbits. The fat around the kidneys and epididymis was taken, and the heart, liver, spleen, and kidney were quickly removed. , brown fat and other tissues and record the weight, the specific data are shown in Table 1.

[0069] Table 1 The effect of the polysaccharide intervention of bean taro leaf on the organ index of mice

[0070]

[0071] According to Table 1, it can be seen that the intervention of taro leaf polysaccharide can alleviate the decline of liver index in obese mice induced by high-fat diet, and at the same time, the intervention of different doses of taro leaf polysaccharide can significantly reduce the peritesticular fat and perirenal fat index of obese ...

Embodiment 3

[0072] Embodiment 3, the effect of bean taro leaf polysaccharide on serum triglyceride, total cholesterol, alanine aminotransferase and aspartate aminotransferase content in obese mice;

[0073] The mice after 12 weeks of intragastric administration in Example 1 were fasted for 24 hours, and the mice were killed by cervical dislocation after blood was taken from the eye sockets. The blood samples were centrifuged at 1500 rpm for 15 minutes, and the serum was taken and preserved, and the glycerol in the serum was analyzed by a Toshiba automatic biochemical analyzer. The contents of triester and total cholesterol were determined, and the specific data are shown in Table 2.

[0074] Table 2 The effect of the intervention of bean taro leaf polysaccharide on the serum indexes of mice

[0075]

[0076] According to Table 2, it can be seen that the intervention of high-dose bean taro leaf polysaccharide can reduce the total cholesterol content in the serum of obese mice induced by...

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Abstract

The invention discloses a fat reducing application of taro leaf polysaccharide. Taro leaf polysaccharide can be used to develop natural fat reducing products in the fields of medicine, food science, and the like. The experiment results show that taro leaf polysaccharide can obviously reduce the weight of fat mice, which have been induced by high fat diet, the contents of triglycerides and total cholesterol in the serum and liver are reduced, and the effect is comprehensive and obvious. Thus, taro leaf polysaccharide can be used to prepare fat reducing food or medicine, which can be used to treat and prevent obesity and related chronic diseases.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a weight-loss application of bean taro leaf polysaccharide. Background technique [0002] Apios americana Medikus is a perennial leguminous plant (Papilionaceae subfamily) native to the eastern part of North America from Canada to the southern part of Florida. Its edible part is the underground tuber, and its protein content is higher than that of other plant tubers. It is a crop with both nutrition and economic value, so it is often used as a staple food by Indians. Bean taro has been successfully introduced in China since 2009, and has been gradually promoted and planted in Fuyang, Jinhua, Longyou, Wenzhou and other places. Studies have shown that different parts of taro (flowers, vines, leaves, tubers) are rich in free amino acids, soluble proteins, polysaccharides, saponins, flavonoids, isoflavones, vitamin C, vitamin E and minerals. Among them, taro leaf has the highest vitamin E c...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61P3/06A61P3/04A23L33/125C08B37/00
CPCA61K31/715A23L33/125A23V2002/00A61K36/48A61P3/04A61P3/06C08B37/0003A23V2200/3262A23V2200/332A23V2250/51
Inventor 郑晓冬楚强俞露霜刘阳阳李永璐陈鹏华
Owner ZHEJIANG UNIV
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