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A space station cell culture bottle and auxiliary device

A technology for cell culture and culture flasks, applied in tissue cell/virus culture devices, biochemical cleaning devices, enzymology/microbiology devices, etc., to achieve good phenotypic expression, shorten experiment time, and simple structure

Active Publication Date: 2022-03-11
天晴干细胞股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention aims to solve the problem that there is currently no method for culturing cells in a certain gravity environment that simulates a certain gravity environment in a specific space microgravity environment, and develops a device suitable for use in an aerospace on-orbit environment for space station cell culture

Method used

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  • A space station cell culture bottle and auxiliary device
  • A space station cell culture bottle and auxiliary device
  • A space station cell culture bottle and auxiliary device

Examples

Experimental program
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specific Embodiment approach 1

[0067] Specific implementation mode one: combine Figure 1 to Figure 13 Describe this embodiment, this embodiment is a space station cell culture bottle, the cell culture bottle includes a culture bottle body 1 and an end cap 3;

[0068] The culture bottle body 1 is a concentric cylinder composed of a plurality of culture bottles 4 with different diameters; each culture bottle 4 is a hollow cylinder; each culture bottle 4 is connected together by ribs 12;

[0069] Each culture bottle 4 is provided with a plurality of chambers in the side wall along the circumference as the culture chamber 2, and the culture bottle 4 is provided with multi-layer culture chamber 2 from top to bottom; , a hydrophobic and moisture barrier film is installed on the vent hole 1;

[0070] The end cap 3 is covered on the culture bottle body 1; the end cap 3 is provided with a plurality of vent holes 2 32, and the vent holes 2 32 communicate with the cultivation chamber 2; the middle of the end cap 3 i...

specific Embodiment approach 2

[0079] Specific implementation mode two: combination Figure 1 to Figure 13 The present embodiment is described. The difference between this embodiment and the first embodiment is that the air hole 5 is equipped with a hydrophobic and moisture barrier membrane made of PVDF material with a pore size of 0.2 μm. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0080] Specific implementation mode three: combination Figure 1 to Figure 13 This embodiment is described. The difference between this embodiment and the specific embodiment 1 is that: the main perfusion channel 3 of the A route and the main perfusion channel 8 of the B route are arranged in an S shape alternately. Others are the same as in the first embodiment.

[0081]Specific implementation mode four: combination Figure 1 to Figure 13 Describe this embodiment, the first difference between this embodiment and the specific embodiment is: the vent holes 32 are arranged between the end cover 1 and the ribs 12 on both sides, and the vent holes 32 are evenly distributed in the gaps between the rings. Others are the same as in the first embodiment.

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Abstract

A space station cell culture flask and an auxiliary device relate to a culture flask and an auxiliary device. The invention aims to solve the problem that there is no method for culturing cells in a space microgravity specific environment simulating a certain gravity environment at present. The invention includes a culture bottle body and an auxiliary operation device matched with it. The cell culture bottle includes an end cap connected with each ring of the culture bottle, and the end cap is provided with ventilation holes; Channel, the cell fluid can be injected into the perfusion channel through the threaded joint, and transported to the culture chamber along the perfusion channel of the bottle body through the tributary channel; the auxiliary device of the cell culture bottle includes a rack and a transmission fixing mechanism on the rack, and the transmission fixing structure includes a limiter. The position bracket, the limit wheel and the frame jointly limit the position of the cell culture flask in the space microgravity environment, and the micromotor drives the runner through the belt to control the rotation speed of the cell culture flask through the computer and the central controller.

Description

technical field [0001] The invention relates to a space station cell culture bottle and an auxiliary device, belonging to the field of space biological cell culture. Background technique [0002] The development of aerospace technology has made experts in life support technology and biology realize that the goal of manned spaceflight is not only short-term flights in low-earth orbit, but also lunar bases, Mars bases, and more distant deep space exploration and resident. The great goal must rely on the bio-regenerative life support system technology. In the closed micro-ecological circulation system artificially designed and constructed by scientists based on the characteristics of the space environment, biotechnology, especially cytology, undertakes the main task of life science. Cultivating cells in space can not only understand the changes in the metabolic activity of various cells in a microgravity environment, so as to control the changes in species and the health of as...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M3/00C12M1/24C12M1/00
CPCC12M23/08C12M29/26C12M35/04
Inventor 张宇张怡刘艳青
Owner 天晴干细胞股份有限公司
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