Macromolecular polymer hydrogel composite Medpor ocular prosthesis holder and preparation method thereof

A technology of high molecular polymers and prosthetic eye sockets, applied in eye implants, coatings, medical science, etc., can solve problems such as exposure and eye socket infection, reduce eye socket exposure, be easy to store, and have a wide range of raw material sources Effect
CN108853581AActive Publication Date: 2018-11-23ZHEJIANG UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
ZHEJIANG UNIV
Publication Date
2018-11-23

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Abstract

The invention discloses a macromolecular polymer hydrogel composite Medpor ocular prosthesis holder and a preparation method thereof. The ocular prosthesis holder is provided with a porous structure with inner pore channel completely penetrating, wherein the porosity is 50 to 85 percent, an inner diameter of the pore channel is 150 to 800 micrometers, and the wall of the pores is modified by adopting hydrogel. The preparation method comprises the following steps: (1) modifying an inner surface of the Medpor ocular prosthesis holder; (2) preparing a macromolecular polymer suspension solution; and (3) under the ngative pressure condition, guiding a macromolecular polymer into the inner surface-modified Medpor ocular prosthesis holder, cross-linking by using a cross-linking agent, thus obtaining the needed hydrogel composite porous ocular prosthesis holder. The ocular prosthesis holder has a bionic extracellular matrix, so that the biological compatibility of the material can be improved,the viscosity and proliferation of the angiogenesis cells can be promoted, the rapid vascularization of the ocular prosthesis holder can be promoted, the complication of the ocular prosthesis holderafter the implanting operation such as exposure and infection of the ocular prosthesis holder can be reduced, and the application value is good.
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Description

technical field

[0001] The invention relates to a Medpor prosthetic eye seat in medical biomaterials and a preparation method thereof, in particular to a high molecular polymer hydrogel composite Medpor prosthetic eye seat and a preparation method thereof. Background technique

[0002] Enucleation is currently the ultimate surgical treatment for absolute glaucoma, severe ocular rupture, and intraocular malignant tumors. Heavy mental and psychological burden. Selecting eye seat implantation to make up for the loss of orbital content and wearing a suitable eye prosthesis is an ideal treatment plan to repair the loss of the eyeball and restore the appearance of the face.

[0003] At present, the clinically used eye socket materials mainly include hydroxyapatite (HA), high-density polyethylene (Medpor), methyl methacrylate (PMMA) and aluminum oxide, among which HA eye socket and Medpor eye socket are the most widely used. widely. The HA eye socket is made of natural coral cal...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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