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Full-nutrition special medical use formula food for trauma patients

A technology of formula food and complete nutrition, applied in the field of medical nutrition, to achieve the effect of lowering serum cholesterol, increasing energy supply ratio, and promoting wound healing

Inactive Publication Date: 2019-01-22
OCEAN UNIV OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the deficiencies of the prior art, the present invention solves the technical problem of negative nitrogen balance in patients with trauma, infection, surgery and other stress states by providing a full-nutrition special medical formula for trauma patients, and improves their Symptoms of nutrient malabsorption

Method used

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  • Full-nutrition special medical use formula food for trauma patients
  • Full-nutrition special medical use formula food for trauma patients
  • Full-nutrition special medical use formula food for trauma patients

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A full-nutrition formula food for special medical purposes aimed at trauma patients, 100g of the specific full-nutrition formula food contains:

[0032] Marine fish collagen peptide 6g, cod protein oligopeptide 6g, whey protein 10g, vegetable oil powder 12g, maltodextrin 30g, isomalt 25g, dietary fiber 6g, minerals 2.22g, vitamin 98.8mg, water 3g.

[0033] The amount of minerals added refers to the "General Rules for Formula Foods for Special Medical Purposes". Among them, the amount of minerals added per 100g of finished formula foods for medical purposes is: sodium 375mg, potassium 510mg, copper 600μg, magnesium 85mg, iron 6.2mg, zinc 6mg, manganese 1400μg, calcium 380mg, phosphorus 260mg, iodine 60μg, chlorine 600mg, selenium 27μg, molybdenum 30μg, chromium 20μg.

[0034]The amount of vitamins to be added is implemented in accordance with the "General Rules for Formulated Foods for Special Medical Purposes". Among them, the amount of vitamins added per 100g of finish...

Embodiment 2

[0037] A full-nutrition formula food for special medical purposes aimed at trauma patients, 100g of the specific full-nutrition formula food contains:

[0038] Marine fish collagen peptide 7g, cod protein oligopeptide 7g, whey protein 8g, vegetable oil powder 13g, maltodextrin 29g, isomalt 25g, dietary fiber 5g, minerals 2.2g, vitamin 102.8mg, water 4g.

[0039] The amount of minerals to be added is implemented in accordance with the "General Rules for Formula Foods for Special Medical Purposes". Among them, the amount of minerals added per 100g of finished formula foods for medical purposes is: sodium 380mg, potassium 500mg, copper 650μg, magnesium 80mg, iron 6mg, zinc 5.5 mg, manganese 1500μg, calcium 400mg, phosphorus 280mg, iodine 64μg, chlorine 550mg, selenium 27μg, molybdenum 25μg, chromium 22μg.

[0040] The amount of vitamins to be added is implemented in accordance with the "General Rules for Formula Foods for Special Medical Purposes". Among them, the amount of vitam...

Embodiment 3

[0043] Safety Evaluation:

[0044] 1. Acute toxicity test

[0045] The formula food for special medical purpose obtained by the present invention has very little toxicity and cannot detect LD50, therefore, this test adopts the maximum tolerated dose (MTD) method.

[0046] 1. Experimental materials

[0047] 20 clean-grade Kunming mice, half male and half male, weighing 20-25g. The test substance is the formula food for special medical purpose obtained from the implementation of Cases 1 and 2.

[0048] 2. Experimental methods and results

[0049] (1) Preliminary experiments showed that the maximum tolerated dose of mice was 150 g / kg when the formula food was made into a paste with warm water.

[0050] (2) Divide into two groups randomly according to body weight, stop feeding and drinking 1 hour before the first gavage, and gavage with 150g / kg·bw formula food, continue to observe for 14 days, and continue to observe for 7 days.

[0051] (3) During the 7 days, the mice did no...

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Abstract

The invention discloses a full-nutrition special medical use formula food for trauma patients. The formula food consists of the following raw materials by mass percentages: 6-7% of marine fish collagen peptide, 6-7% of cod protein oligopeptide, 8-10% of whey protein, 12-13% of vegetable oil powder, 28-30% of maltodextrin, 23-25% of isomalt, 5-6% of dietary fiber, 2.2-2.22% of mineral matter, 0.098-0.103% of vitamin, and 3-4% of moisture. The food uses marine fish collagen peptide and cod protein oligopeptide as a matrix, and creatively uses the matrix as a nutrient component of a nitrogen source, and the research and development of the special medical use formula for trauma, infection, surgery and other stress states fundamentally correct the negative nitrogen balance in patients and improve symptoms such as malabsorption.

Description

technical field [0001] The invention belongs to the technical field of medical nutrition, and in particular relates to a full-nutrition special medical formula food for trauma patients. Background technique [0002] Stress states such as trauma, infection, and surgery have a huge impact on human health. Improper handling can cause symptoms such as high fever, swelling, pain, and ulceration. Severe cases can cause serious consequences such as tissue necrosis, coma, shock, and systemic poisoning. patient's death. After traumatic stress, the body will undergo a series of metabolic changes, manifested as increased resting energy expenditure (REE), hyperglycemia, enhanced gluconeogenesis, enhanced protein breakdown, accelerated fat mobilization, negative nitrogen balance, and a decrease in the overall level of body cells. When the body is under traumatic stress, neuroendocrine function, cytokine production, and metabolism will change. There may be hypermetabolism, and the net de...

Claims

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Application Information

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IPC IPC(8): A23L33/18A23L33/19A23L33/21A23L33/16A23L33/155A23L33/15A23L33/125A23L33/115
CPCA23L33/115A23L33/125A23L33/15A23L33/155A23L33/16A23L33/18A23L33/19A23L33/21
Inventor 侯虎杨亭亭樊燕
Owner OCEAN UNIV OF CHINA
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