Bletilla compound preparation for treating newborn diaper rash and preparation method

Abstract

The invention discloses a bletilla compound preparation for treating newborn diaper rash. The bletilla compound comprises the following components: 35-50 parts of bletilla polysaccharide, 600-800 parts of medical injection tea oil, 20-100 parts of 10% chlorhexidine gluconate and 80-150 parts of pure water. A preparation method thereof comprises the following steps: weighting 35.0g bletilla polysaccharide with purity is more than or equal to 93.5%; adding 200ml medical injection tea oil and 80-150ml deionized water and heating to 70 DEG C; adding 30ml 10% chlorhexidine gluconate (or chlorhexidine acetate) and stirring; adding medical injection tea oil, keeping 1000ml constant volume, stirring at rate of 4000rpm, uniformly mixing and then sterilizing, thereby acquiring the bletilla compoundpreparation. The bletilla compound preparation is capable of forming a protecting layer on injured skin surface of newborn buttocks, reducing bacteria invasion, obviously restraining or killing pathogenic bacteria, such as escherichia coli and staphylococcus aureus, and boosting hemostasis and healing of injured skin.

Description

technical field [0001] The present disclosure generally relates to the field of medical drugs, in particular to a bletilla striata compound preparation for treating neonatal red buttocks and a preparation method thereof. Background technique [0002] Neonatal red buttocks, also known as diaper rash, neonatal diaper dermatitis, often near the anus, buttocks, perineum, mostly because the baby's diapers are not changed frequently or washed cleanly, and prolonged contact with the baby's skin irritates the baby's skin; the texture of the diaper is hard, It is caused by local friction, manifested as large areas of erythema, papules, or erosive exudate with clear boundaries on the diaper site, which is prone to secondary bacterial or Candida infection and aggravated, and severe complications may even occur, which is life-threatening. In severe cases, especially malnourished infants with chronic diarrhea, skin ulcers may occur. The traditional treatment method is to smear tannic ac...

AI Technical Summary

Problems solved by technology

The traditional treatment method is to apply tannic acid ointment, or a three-in-one powder drug covering with a mixture of boric acid, zinc oxide, and talcum powder, and the treatment effect is poor.

At present, functional dressings and liquid dressings are mostly used, mainly some imported liquid dressings (such as 3M Cavilon or 3M Painless Protective Film Spray, liquid dressing Saifurun); on the one hand, they are not therapeutic drugs, on the other hand It has many shortcomings such as single function or limitation, and the treatment effect on the red buttocks of newborns that has occurred is poor.

For example, although the liquid dressing Saifurun can cover, isolate and protect the skin by forming a lipid protective film on the skin surface, and can promote the repair of injured skin or skin in risky areas, its function is limited to skin protection. Bacterial function is low, there is no bactericidal and antibacterial effect, and there is no effect of hemostasis and wound healing

Some chemical drugs added to liquid dressings, such as medical antibacterial dressings for infant skin (trade name: Ximeiying) are bactericidal agents based on dialkyl quaternary ammonium salts (cations), which have strong permeability, and dialkyl quaternary ammonium Salt itself has certain side effects and irritation, and the body will produce toxic side effects after absorption, which is unsafe for newborns; some liquid dressings use organic solvents, which are highly irritating and prone to allergies or pain; some are added with chitosan or Honeysuckle and other traditional Chinese medicine extracts have antibacterial or bactericidal effects, but have poor hemostatic and wound healing effects

Images