Skin-whitening moisturizing crystal gel and preparation method thereof, and tyrosinase inhibitor

A tyrosinase and inhibitor technology, applied in the field of cosmetics, can solve the problems of single action of arbutin, large skin irritation, easy discoloration of kojic acid, etc., and achieve the effects of excellent moisturizing effect, easy access and simple operation.

Inactive Publication Date: 2019-03-08
GUANGZHOU KENENG COSMETICS RES CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In view of the problems in the prior art that hydroquinone is very irritating to the skin; kojic acid is easy to change color and has a certain degree of irritation to the skin; arbutin has a single effect and poor effect, etc., the present invention firstly provides a whitening moisturizing crystal Dew, the whitening and moisturizing crystal dew of the present invention can reduce melanin production and has excellent whitening effect

Method used

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  • Skin-whitening moisturizing crystal gel and preparation method thereof, and tyrosinase inhibitor
  • Skin-whitening moisturizing crystal gel and preparation method thereof, and tyrosinase inhibitor
  • Skin-whitening moisturizing crystal gel and preparation method thereof, and tyrosinase inhibitor

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no. 1 approach

[0035] The first embodiment of the present invention provides a tyrosinase inhibitor, which includes: ginseng extract and resurrection grass extract. The tyrosinase inhibitor of the invention can well inhibit the activity of tyrosinase, and has excellent whitening effect when used in cosmetics.

[0036] Ginseng (Panax ginseng C.A. Meyer) is a perennial herb of Araliaceae. Ginseng is one of the most potential medicinal plant resources in Changbai Mountain.

[0037] Ginseng contains a variety of chemical components, such as: ginsenosides, ginseng polysaccharides, ginseng proteins and polypeptides. Among them, ginsenoside (Ginsenoside), a sterol compound, is a triterpene saponin with a dammarane-type chemical structure and a tetracyclic triterpene as the main structure. Ginsenoside is one of the representative active ingredients in ginseng, which widely exists in plants of the genus Panax. Ginseng polysaccharide is another kind of effective active ingredient of ginseng, and it ...

no. 2 approach

[0045] The second embodiment of the present invention provides a whitening and moisturizing crystal lotion containing the tyrosinase inhibitor according to the first embodiment of the present invention. The whitening and moisturizing crystal dew of the present invention has crystal gel texture, good ductility, easy penetration, good moisturizing effect, and is very suitable for dry skin. In addition, by adding the tyrosinase inhibitor of the present invention to the whitening and moisturizing crystal dew of the present invention, the whitening and moisturizing crystal dew of the present invention can greatly reduce the generation of melanin.

[0046] In the present invention, based on the total mass of the whitening and moisturizing crystal dew, the added amount of the tyrosinase inhibitor is 0.01-15%, preferably 0.1-14%, for example: the tyrosinase inhibitor The addition amount of agent is 0.5%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12% etc. When the added amount of ...

no. 3 approach

[0067] The third embodiment of the present invention provides a preparation method of whitening and moisturizing dew, which is characterized in that it includes the step of mixing the components of the whitening and moisturizing dew.

[0068] Specifically, the preparation method of the whitening and moisturizing crystal dew of the present invention may comprise the following steps:

[0069] 1. Add water, humectant, thickener, optional chelating agent, and some preservative raw materials into the stirring pot, stir and heat to 75-85°C;

[0070] 2. Cool to 40-45°C, add pH adjuster, solubilizer, tyrosinase inhibitor, optional antioxidant, skin conditioner and remaining preservative and stir evenly;

[0071] 3. Cool to 35-40°C, discharge after passing the inspection, and let stand for 12-48 hours;

[0072] 4. After passing the inspection, sub-package, pack, re-inspect, and put the finished product into storage.

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Abstract

The invention relates to a skin-whitening moisturizing crystal gel and a preparation method thereof, and a tyrosinase inhibitor. The skin-whitening moisturizing crystal gel is characterized by containing the tyrosinase inhibitor. On the basis of a total mass of the skin-whitening moisturizing crystal gel,,the dosage of the tyrosinase inhibitor is 0.01-15%. Preferably, the skin-whitening moisturizing crystal gel also containing a combination of one or more of a moisturizing agent, a thickening agent, a pH regulator, a solubilizer, a skin conditioner, a preservative and an aromatic agent, wherein on the basis of the total mass of the skin-whitening moisturizing crystal gel, the dosage of the moisturizing agent is 0.01-25%; the dosage of the thickening agent is 0.02-0.8%; the dosage of the pHregulator is 0.01-1%; the dosage of the solubilizer is 0.01-0.2%; the dosage of the skin conditioner is 0.01-10%; the dosage of the preservative is 0.01-1.5%; and the dosage of the aromatic agent is0.005-0.5%. The skin-whitening moisturizing crystal gel provided by the invention is capable of reducing melanogenesis and has an excellent whitening effect. Besides, the skin-whitening moisturizing crystal gel has an excellent moisturizing effect and a mild formula and has no side effect to a human body.

Description

technical field [0001] The invention relates to a whitening and moisturizing crystal dew, a preparation method thereof and a tyrosinase inhibitor, belonging to the field of cosmetics. Background technique [0002] Melanin is mainly produced by melanocytes in the basal layer of human skin epidermis, which can reduce the damage of ultraviolet rays to the skin. The content and distribution of melanin determine the color of the skin. However, the abnormal accumulation of melanin in the basal layer will cause hyperpigmentation and cause melasma, freckles, age spots, etc., affecting people's quality of life. With the deepening of research on melanin biosynthesis, researchers found that tyrosinase plays an important role in melanin biosynthesis. It is the main rate-limiting enzyme in the process of converting tyrosine and dopa to melanin. Its overexpression is the main cause of hyperpigmentation. Therefore, inhibiting the activity of tyrosinase can block the biosynthesis reactio...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/9741A61K8/73A61K8/34A61K8/39A61K8/86A61K8/42A61K8/49A61K8/81A61K8/65A61K8/64A61K8/68A61K8/9706A61K8/9711A61K8/9722A61K8/9717A61K8/9794A61K8/44A61K8/92A61K8/41A61Q19/00A61Q19/02
CPCA61K8/345A61K8/39A61K8/41A61K8/42A61K8/44A61K8/4913A61K8/645A61K8/65A61K8/68A61K8/73A61K8/735A61K8/8147A61K8/8152A61K8/86A61K8/922A61K2800/48A61K2800/49A61K2800/5922A61K2800/782A61K2800/85A61Q19/00A61Q19/02A61K8/9706A61K8/9711A61K8/9717A61K8/9722A61K8/9741A61K8/9789A61K8/9794
Inventor 杨登亮林盛杰刘德海戴嘉彬马静蓉张伟杰张楚标
Owner GUANGZHOU KENENG COSMETICS RES CO LTD
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