Application of 18F-SFB-CML and method for detecting atherosclerosis

A technique for atherosclerosis and purpose, applied in the field of nuclear medicine, can solve the problems of ineffective monitoring of plaque composition and vulnerability, poor specificity and sensitivity of F-FDG, limited temporal resolution and spatial resolution, etc. Achieve the effect of being conducive to rapid imaging analysis, not easy to degrade, and easy to high-resolution imaging
CN109453401AActive Publication Date: 2019-03-12AFFILIATED HOSPITAL OF JIANGSU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
AFFILIATED HOSPITAL OF JIANGSU UNIV
Publication Date
2019-03-12

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Abstract

The invention relates to the technical field of nuclear medicine, and relates to application of 18F-SFB-CML and a method for detecting atherosclerosis. Firstly, the invention provides the applicationof 18F-SFB-CML in preparing a product for detecting atherosclerotic diseases; the method for detecting atherosclerosis is further provided; the method is to use 18F-SFB-CML as a photographic developerto obtain the location, size, and vascular stenosis degree information of an atherosclerotic plaque by molecular imaging scanning. The 18F-SFB-CML as the photographic developer can accurately reflectthe size of the plaque and the vascular stenosis degree, and can effectively trace the atherosclerotic plaque.
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Description

technical field

[0001] The invention relates to the technical field of nuclear medicine, and relates to a 18 Use of F-SFB-CML and method for detecting atherosclerosis. Background technique

[0002] Atherosclerosis (AS) is caused by multiple factors, and its pathogenesis is complex. At present, traditional imaging examinations cannot effectively monitor plaque composition and vulnerability, while molecular imaging can accurately determine plaques and has the potential to identify vulnerable and high-risk plaques.

[0003] So far, the commonly used methods include (1) nuclear medicine imaging: it is a relatively mature method for molecular imaging of AS plaques. Imaging instruments include positron emission computed tomography (PET) and single photon emission computed tomography (SPECT), but the poor spatial resolution limits the application of this method. (2) CT imaging: However, the temporal resolution and spatial resolution of CT imaging are limited, and the reliability...

Claims

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