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Compound nutrient enhancer embedded with choline hydrogen tartrate and preparation method thereof

A technology of choline bitartrate and nutritional fortifier, which is applied to non-active ingredients in medical preparations, pharmaceutical formulas, digestive systems, etc. Good fluidity, mild conditions, the effect of avoiding vitamin reactions

Inactive Publication Date: 2019-04-02
NANTONG LICHENG BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, it is also necessary to be cautious when adding solid preparations containing choline bitartrate to the product. Although the product quality and indicators are stable at the initial stage of mixing choline bitartrate with other raw materials, after a period of storage, choline bitartrate will absorb other raw materials. Moisture, agglomeration, reaction with other raw materials, such as mixing with vitamin A, vitamin D, vitamin B12 will appear color spots, seriously affecting product quality

Method used

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  • Compound nutrient enhancer embedded with choline hydrogen tartrate and preparation method thereof
  • Compound nutrient enhancer embedded with choline hydrogen tartrate and preparation method thereof
  • Compound nutrient enhancer embedded with choline hydrogen tartrate and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of the compound nutritional fortifier embedding choline bitartrate with a design content of 15%:

[0025] S1: Add 45.75kg of water into the dissolving pot, heat the water temperature to 55°C, slowly add 15.3kg of choline bitartrate and 3kg of corn starch into the dissolving pot, mix at a speed of 40r / min for 10min, and use it as solution A for later use;

[0026] S2: Add 199.25kg of water into another dissolving pot, heat the water temperature to 55°C, slowly add 5kg of sodium starch octenyl succinate and 5kg of mono- and diglyceride fatty acid esters into the dissolving pot at 40r / min Mix for 10 minutes at a rotating speed of 10 min, and use it as solution B;

[0027] S3: Shut down and introduce solution A into solution B, start the machine and continue mixing at a speed of 40r / min for 10min, and use it as solution C;

[0028] S4: The solution C was emulsified and stirred at room temperature with a high-shear dispersing emulsifier, and emulsified at a ...

Embodiment 2

[0033] The preparation of the compound nutritional fortifier embedding choline bitartrate with a design content of 25%:

[0034] S1: Add 65.75 kg of water into the dissolving pot, heat the water temperature to 55°C, slowly add 25.3 kg of choline bitartrate and 1 kg of corn starch into the dissolving pot, mix at a speed of 40 r / min for 10 min, and use it as solution A for later use;

[0035] S2: Add 179.25kg of water into another dissolving pot, heat the water temperature to 55°C, slowly add 5kg of sodium starch octenyl succinate and 5kg of mono- and diglyceride fatty acid esters into the dissolving pot at 40r / min Mix for 10 minutes at a rotating speed of 10 min, and use it as solution B;

[0036] S3: Shut down and introduce solution A into solution B, start the machine and continue mixing at a speed of 40r / min for 10min, and use it as solution C;

[0037] S4: The solution C was emulsified and stirred at room temperature with a high-shear dispersing emulsifier, emulsified at a...

Embodiment 3

[0042] The preparation of the compound nutritional fortifier embedding choline bitartrate with a design content of 0.01%:

[0043] S1: Add 20.75kg of water into the dissolving pot, heat the water temperature to 60°C, slowly add 0.01kg of choline bitartrate and 2kg of corn starch into the dissolving pot, mix at a speed of 20r / min for 20min, and use it as solution A for later use;

[0044] S2: Add 224.25kg of water into another dissolving pot, heat the water temperature to 60°C, slowly add 5kg of sodium starch octenyl succinate and 5kg of mono- and diglyceride fatty acid esters into the dissolving pot at 20r / min Mix at a rotating speed of 20 minutes, and use it as solution B;

[0045] S3: Shut down and introduce solution A into solution B, start the machine and continue mixing at a speed of 20r / min for 20min, and use it as solution C;

[0046] S4: The solution C was emulsified and stirred at room temperature with a high-shear dispersing emulsifier, and emulsified at a speed of ...

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Abstract

The invention discloses a compound nutrient enhancer embedded with choline hydrogen tartrate and a preparation method thereof, wherein the preparation method comprises the steps: S1, weighing cholinehydrogen tartrate and corn starch, dissolving in water, and heating and stirring to dissolve, to obtain a solution A; S2, weighing starch sodium octenylsuccinate and mono-diglycerol fatty acid ester,dissolving in water, and heating and stirring to dissolve, to obtain a solution B; S3, mixing and stirring the solution A and the solution B, to obtain a solution C; S4, emulsifying and stirring the solution C at room temperature to obtain an emulsified solution D; S5, weighing maltodextrin, adding maltodextrin into the emulsified solution D, and heating and stirring to obtain an emulsified solution E; S6, carrying out spray drying treatment of the emulsified solution E to obtain powder; and S7, weighing calcium triphosphate, and mixing with the powder to obtain the compound nutrient enhancer.The prepared choline hydrogen tartrate compound nutrient enhancer is an embedding product, does not easily absorb moisture and is not easily caked, has high stability and good mixing property, and cannot react with other raw materials when being mixed with other raw materials.

Description

technical field [0001] The invention relates to a compound nutrition enhancer and a preparation method thereof, in particular to a compound nutrition enhancer embedding choline bitartrate and a preparation method thereof. Background technique [0002] As a vitamin product, choline bitartrate is widely used in medicines, health care products and food nutrition additions. Choline bitartrate can promote the transformation of phospholipids, accelerate fat transfer and choleretic effect; it has a good curative effect on hepatitis, liver function decline, early liver cirrhosis and pernicious anemia; it is also often added to infant or children's formula food as a nutritional supplement middle. [0003] Choline bitartrate is very easy to absorb moisture, because it is easily soluble in water, difficult to dissolve in ethanol, and insoluble in ether, chloroform and benzene, so its application is greatly limited. In practical application, since the choline bitartrate group absorbs ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L29/00A23L29/10A23L29/30A23L33/10A23P10/30A61K47/36A61K47/14A61K47/02A61P1/16A61P7/06A61P3/02
CPCA61K47/02A61K47/14A61K47/36A23L29/015A23L29/10A23L29/30A23L29/35A23L33/10A23P10/30A61P1/16A61P3/02A61P7/06
Inventor 张光伟周蓉蓉张霞季晨明
Owner NANTONG LICHENG BIOLOGICAL ENG
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