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Medicine for treating pharyngitis and preparation method of medicine

A technology for medicine and pharyngitis, applied in the field of medicine for treating pharyngitis and its preparation, can solve the problems of slow onset, easy repetition and many side effects, etc.

Active Publication Date: 2019-04-02
MUDANJIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, symptomatic treatment is mostly used in the treatment of pharyngitis, such as quitting smoking and alcohol, avoiding dust inhalation, anti-inflammatory treatment, and antipyretic treatment for patients with fever symptoms. A larger dosage is required, although it has a certain effect on the treatment of pharyngitis, but there are problems such as slow onset of action, easy repetition, and many side effects
[0004] Cycyanidin galactoside is a flavonoid compound. Modern pharmacological studies have shown that cyanidin galactoside has various biological activities such as anti-oxidation, anti-mutation, anti-tumor, and prevention and treatment of cardiovascular diseases, and can be widely used It is used to prevent senile dementia, anti-tumor, hypoglycemic, anti-atherosclerosis, etc., but there is no report on the application of cyanidin galactoside in the treatment of pharyngitis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1: a kind of buccal tablet for the treatment of pharyngitis

[0026] 12 parts of cyanidin galactoside, 15 parts of microcrystalline cellulose, 6 parts of hydroxypropyl methylcellulose, 30 parts of mannitol, 30 parts of sorbitol, 5 parts of sodium carboxymethyl starch, 2 parts of menthol part, an appropriate amount of magnesium stearate, prepared according to the following method:

[0027] (1) material preparation: take each raw material according to the formula;

[0028] (2) Preparation: mix cyanidin galactoside with microcrystalline cellulose, hydroxypropyl methylcellulose, mannitol, sorbitol, sodium carboxymethyl starch and menthol and then wet granulate, After passing through a 12-mesh sieve for granulation, add magnesium stearate, mix evenly, and then compress into tablets to obtain the buccal tablet for treating pharyngitis of the present invention.

Embodiment 2

[0029] Embodiment 2: a kind of buccal tablet for the treatment of pharyngitis

[0030] 12 parts of cyanidin galactoside, 6 parts of dandelion sterol, 10 parts of microcrystalline cellulose, 8 parts of hydroxypropyl methylcellulose, 40 parts of mannitol, 30 parts of sorbitol, 5 parts of sodium carboxymethyl starch 2 parts, 2 parts of menthol, appropriate amount of magnesium stearate, prepare according to the method of embodiment 1 to get the buccal tablet for the treatment of pharyngitis of the present invention.

Embodiment 3

[0031] Embodiment 3: a kind of capsule for the treatment of pharyngitis

[0032] 12 parts of cyanidin galactoside, 6 parts of dandelion sterol, 40 parts of microcrystalline cellulose, 6 parts of sodium carboxymethyl cellulose, 8 parts of crospovidone, appropriate amount of magnesium stearate, prepared according to the following method:

[0033] (1) material preparation: take each raw material according to the formula;

[0034] (2) Preparation: mix cyanidin galactoside, dandelion sterol, microcrystalline cellulose, sodium carboxymethyl cellulose, and crospovidone evenly, then wet granulate, pass through a 12-mesh sieve for granulation, add hard After the magnesium fatty acid is mixed evenly, it is filled in the gelatin capsule shell to obtain the capsule for treating pharyngitis of the present invention.

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PUM

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Abstract

The invention relates to a medicine for treating pharyngitis and a preparation method of the medicine. The medicine for treating the pharyngitis takes cyanidin 3-galactoside as an active component; cyanidin 3-galactoside has an obvious prevention and treatment effect on the pharyngitis; after taraxasterol is added, the pharyngitis treatment effect of cyanidin 3-galactoside is strengthened; particularly when a ratio of cyanidin 3-galactoside to taraxasterol is 6:5, the treatment effect is most excellent; and the medicine has the obviously better treatment effect than cyanidin 3-galactoside or taraxasterol used independently, and shows that cyanidin 3-galactoside and taraxasterol have a synergetic effect when cyanidin 3-galactoside and taraxasterol are used in combination for treating the pharyngitis.

Description

technical field [0001] The invention belongs to the field of medicines, in particular to a medicine for treating pharyngitis and a preparation method thereof. Background technique [0002] Pharyngitis (Pharyngitis) refers to the general designation of inflammation caused by various microorganisms infecting the pharynx. It can be divided into acute pharyngitis and chronic pharyngitis. Acute pharyngitis is mostly caused by bacterial or viral infection. coccus, pneumococcus, staphylococcus, etc., the viruses commonly include influenza virus, adenovirus, etc. Chronic pharyngitis is mainly caused by repeated episodes of acute pharyngitis, or chronic rhinitis, sinusitis, excessive smoking and alcohol, dust, chemical stimulus etc. The main clinical symptoms of pharyngitis include: dry throat, sore throat, obvious foreign body sensation in the throat, painful swallowing, and obvious congestion in the throat. Along with the appearance of air pollution, the incidence of pharyngitis ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61P11/04A61P31/12A61P31/04
CPCA61K31/7048A61P11/04A61P31/04A61P31/12
Inventor 岳文江王振东陈昕尹国华李莲娣曾婷
Owner MUDANJIANG MEDICAL UNIV