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A traditional Chinese medicine composition for treating functional dyspepsia and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation for the treatment of functional dyspepsia, can solve the problems of low extraction efficiency and affecting the efficacy of products, etc.

Active Publication Date: 2021-08-10
TONGYAO PHARMA GROUP CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the existing preparation method of Zhishi Xiaopi Pills has low extraction efficiency for synephrine, hesperidin, naringin, berberine hydrochloride, etc., which seriously affects the efficacy of the product

Method used

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  • A traditional Chinese medicine composition for treating functional dyspepsia and preparation method thereof
  • A traditional Chinese medicine composition for treating functional dyspepsia and preparation method thereof
  • A traditional Chinese medicine composition for treating functional dyspepsia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The preparation of embodiment 1 Chinese medicine composition of the present invention

[0034] (1) Take 500g Citrus aurantii, 400g Magnolia officinalis, 300g Atractylodes Rhizoma Atractylodes Rhizome, 200g dried ginger, grind them into fine powder, pass through a 40 mesh sieve, add 10 times the amount of water, soak for 1 hour, extract the volatile oil with steam distillation for 6 hours, collect the volatile oil, Dissolve with an equal amount of ethanol and set aside; weigh 8 times the amount of volatile oil in cyclodextrin to make a saturated aqueous solution at 45-55°C, add volatile oil while stirring, and keep stirring at 45-55°C for 3 hours, and refrigerate overnight. Filter and dry to obtain extract A145g.

[0035] (2) Take 400g Magnolia Bark, 300g Atractylodes Rhizoma Atractylodes Rhizome and 500g Codonopsis Codonopsis, grind them into coarse powder, perform flash extraction with 70% ethanol 2-4 times for 4 minutes each time, filter the dregs after extraction, an...

Embodiment 2~8

[0039] Embodiment 2~8 Chinese medicine composition

[0040] The formulation composition is shown in Table 1.

[0041] Table 1 Embodiment 2~8 Chinese medicine composition formula composition

[0042]

[0043]

[0044] The preparation method is the same as in Example 1.

Embodiment 9

[0045] Embodiment 9 capsules of the present invention

[0046] Get the Chinese medicine composition of Example 1 and add lactose to 1000g, granulate, and fill 1000 capsules.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating functional dyspepsia and a preparation method thereof. The present invention uses Zhishi Xiaopi Pills as a raw material, and for the first time adopts steam distillation extraction, ethanol flash extraction, ethanol heating and reflux extraction combined with macroporous adsorption resin, polyamide resin, sodium chloride salting out and other technical means to treat different medicinal flavors. Enrichment, separation, and purification of the effective parts of the product can maximize the extraction of active ingredients such as synephrine, hesperidin, naringin, and berberine hydrochloride in the raw materials. The traditional Chinese medicine composition of the present invention is obtained after the effective parts are enriched, separated and purified by the preparation method of the present invention and combined according to a specific ratio. Experiments show that the Chinese medicinal composition has a significant therapeutic effect on functional dyspepsia and chronic gastritis. It is obviously better than Zhishi Xiaopi Pill and Zhishi Xiaopi Decoction made by traditional technology.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extraction, in particular to a traditional Chinese medicine composition for treating functional dyspepsia and a preparation method thereof. Background technique [0002] Zhishi Xiaopi Wan, also known as Shixiao Wan, is a digestive agent. Its prescription is: Citrus aurantium (stir-fried) 100g, Atractylodes macrocephala (stir-fried) 60g, Pinellia 60g, Coptidis 100g, Codonopsis 50g, licorice (made) 40g, Poria cocos 40g, Magnolia officinalis (made) 80g, malt (fried) 40g, dried ginger 40g. This prescription comes from "The Secret Collection of the Lanshi" written by Li Dongyuan. It has the effects of eliminating pimples and fullness, strengthening the spleen and harmonizing the stomach. Indications of spleen deficiency and qi stagnation, cold and heat syndrome. Heart fullness, no desire to eat, fatigue, poor stool, greasy and yellowish fur, stringy pulse. Clinically, it is comm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K47/69A61P1/04A61P1/14
CPCA61K36/076A61K36/284A61K36/344A61K36/484A61K36/575A61K36/718A61K36/752A61K36/8888A61K36/9068A61K2236/331A61K2236/333A61K2236/55A61K47/6951A61P1/04A61P1/14A61K2300/00
Inventor 唐晓桐高嵩田淋淋吴萍赵源慧徐云徐建
Owner TONGYAO PHARMA GROUP CORP
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