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Processing agent for medical magnesium alloy implant and use method thereof

An implant, magnesium alloy technology, applied in the field of biomedical material treatment agent, can solve the problems of complex preparation process, huge influence on the properties of the final coating product, etc., and achieves simple treatment process, easy industrialization and application, and uniform film layer. Effect

Inactive Publication Date: 2019-05-21
CHINA BAOWU STEEL GRP CORP LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the process involved in this patent document still requires a multi-step reaction process, the preparation process is relatively complicated, and the reaction conditions have a great influence on the properties of the final coating product.

Method used

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  • Processing agent for medical magnesium alloy implant and use method thereof
  • Processing agent for medical magnesium alloy implant and use method thereof
  • Processing agent for medical magnesium alloy implant and use method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0067] Table 1 lists the proportions of components in the treatment agents for medical magnesium alloy implants of Examples 1-5.

[0068] Table 1.

[0069]

[0070]

[0071] It should be noted that when preparing the treatment agent for medical magnesium alloy implants, a salt solution containing gallium ions and a salt solution containing phosphate ions can be mixed and added with water to obtain the required treatment agent solution, or a mixture of ionic salt and phosphoric acid can be used. The root ion salt is dissolved in water to obtain the required solution, and the gallium ion salt can also be dissolved in a salt solution containing phosphate ions and then added to constant volume to obtain the desired solution. In addition, the phosphate ion salt can also be dissolved in a salt solution containing gallium ions. After the saline solution, add water to make up to volume to obtain the desired solution.

[0072] The treatment agent for medical magnesium alloy impl...

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Abstract

The invention discloses a processing agent for a medical magnesium alloy implant. The processing agent comprises 0.01-0.5mol / l gallium ion, 0.005-0.5mol / l phosphate anion, and a buffering agent for regulating the pH of the processing agent to be 1.0-5.0, wherein the molar ratio of gallium ion to phosphate anion is 1: (0.6-1.2). Additionally, the invention also discloses a use method of the processing agent for the medical magnesium alloy implant. The method comprises the following steps: 1) preprocessing the surface of the medical magnesium alloy implant; 2) implanting the medical magnesium alloy implant subjected to surface preprocessing into the processing agent for the medical magnesium alloy implant for a period of time; and 3) moving out the medical magnesium alloy implant; washing with water; and drying. Additionally, the invention also discloses the medical magnesium alloy implant which is processed by the abovementioned use method. The processing agent is high in biocompatibility and sterilizing effect.

Description

technical field [0001] The invention relates to a treatment agent and its application method, in particular to a biomedical material treatment agent and its application method. Background technique [0002] Among medical bone repair and bone implant materials, stainless steel, cobalt-chromium-molybdenum alloys, titanium, and titanium alloys have become widely used clinical biomaterials due to their excellent mechanical properties, biocompatibility and corrosion resistance. However, the main mechanical properties of the above three conventional metal-based biomaterials, such as the modulus of elasticity, do not match those of human bones, and it is easy to produce a "stress shielding" effect, which in turn causes atrophy or even loosening of the bone tissue in contact with the implant Symptoms, and eventually cause the implant to fall off and fail. The required follow-up repair surgery will inevitably bring an unbearable financial burden and pain to the patient. At the same...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C23C22/08A61L27/04A61L27/32A61L27/50A61L27/54
Inventor 徐世伟陈晓博唐伟能柯聪尼克·波比利斯
Owner CHINA BAOWU STEEL GRP CORP LTD