Method for preparing heterogeneous biological amniotic membrane product

A kind of amniotic membrane and biological technology, applied in medical science, prosthesis, etc., can solve the problems affecting the clinical use effect, and achieve the effect of simple preparation method and wide source
CN109939263AInactive Publication Date: 2019-06-28广州锐澄医疗技术有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
广州锐澄医疗技术有限公司
Publication Date
2019-06-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a method for preparing a heterogeneous biological amniotic membrane product. The method comprises the following main steps of 1, placenta acquisition and peeling; 2, cleaning sterilization and fixation; 3, irradiation inactivation; 4, packaging and program freezing. Compared with the prior art, the method has the following advantages that the product related derives from heterogeneous mammals (including pigs, cattle, sheep and the like), and raw materials are controllable and scalable; animal-derived materials are subjected to non-destructive treatment, and a natural amniotic membrane structure and active ingredients are maintained as much as possible; under the protection of preservation liquid with specific functions, the sterilization and inactivation of the product are achieved by irradiation, and the safety and effectiveness of the product are both achieved. The method brings a novel solution to the raw material source and standardization problem of the biological amniotic membrane product, and also provides a reference method and technical way for the high value reuse of the traditional animal husbandry biological waste.
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Description

technical field

[0001] This project involves the technical field of animal-derived medical device materials, specifically a method for preparing a heterogeneous biological amniotic membrane product. Background technique

[0002] Amniotic membrane is used as an immune-privileged biological graft. Natural amniotic membrane has a large number of different components such as collagen, fibronectin, laminin and proteoglycan. In addition, natural amniotic membrane contains a variety of nutritional factors, such as transforming growth factor-β (TGF-β), transforming growth factor-α (TGF-α), basic growth factor (bFGF), epidermal growth factor (EGF), nerve growth factor Hepatocyte growth factor (NGF), brain-derived neurotrophic factor (BDNF), hepatocyte growth factor (HGF) and keratinocyte growth factor (KGF), etc., can promote cell growth, proliferation and differentiation. Amniotic membrane can act as a "basement membrane" to facilitate cell adhesion and growth to promote epithelial...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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