Headspace-gas chromatography/mass spectrometry (HS-GC/MS) measurement method of eleven types of volatile harmful substances in student supplies

Abstract

The invention relates to a headspace-gas chromatography / mass spectrometry (HS-GC / MS) measurement method of eleven types of volatile harmful substances in student supplies, and belongs to the technicalfield of detection and risk assessment of the harmful substances in the student supplies. The HSGC-MS selection ion quantitative measurement method is established so as to measure the eleven types ofvolatile harmful substances such as 1,1-dichloroethane, trichloromethane, 1,1,1-trichloroethane, cyclohexane, carbon tetrachloride, benzene, methyl cyclohexane, toluene and xylene in the student supplies. After a sample is subjected to headspace at 70 DEG C for 30 min, toluene -d8 serves as the internal standard, then gas in a headspace sample injector is directly injected to a GC / MS system, andthe volatile harmful substances in the student supplies are qualitatively and quantitatively analyzed through the headspace sample injector and a gas chromatography-mass spectrometer. According to themethod, the detection limit is 0.02-0.18 mg / kg, the quantitative limit is 0.07-0.60 mg / kg, the standard recovery rate is 93.33-105.8%, and the relative standard deviation is smaller than 10%. The tedious step of solvent extraction is avoided, by selecting ion detection quantification, interference factors are few, operation is easy, and sensitivity and repeatability are good.

Description

technical field [0001] The present invention relates to a HS-GC / MS (Headspace-Gas Chromatography-Mass Spectrometry) assay method for 11 kinds of volatile harmful substances in school supplies, and more specifically relates to a HS-GC / MS (Headspace-Gas Chromatography-Mass Spectrometry) method for determining Gas chromatography-mass spectrometry) method for the determination of 1,1-dichloroethane, chloroform, 1,1,1-trichloroethane, cyclohexane, carbon tetrachloride, benzene, methylcyclohexane The method for 11 kinds of volatile harmful substances such as hexane, toluene, o-xylene, m-xylene and p-xylene belongs to the technical field of detection and risk assessment of harmful substances in school supplies. Background technique [0002] Student supplies such as watercolor pens, pen refills, marker pens, erasers, correction fluid zipper file bags, plastic rulers, stationery boxes (bags), plastic book covers (films), etc. are related to students’ life, growth and education. impo...

AI Technical Summary

Problems solved by technology

Volatile toxic and harmful substances in typical student supplies such as 1,1-dichloroethane, chloroform, 1,1,1-trichloroethane, cyclohexane, carbon tetrachloride, benzene, methylcyclohexane Alkanes, toluene, o-xylene, meta-xylene, and p-xylene have a greater impact on children's health, especially children will introduce these compounds into the body through inhalation, sucking, and biting, which will cause chronic poisoning of the human body, especially It can cause diseases in the nervous system and blood system, and cause potential harm to children's health

Since the current national mandatory standards do not set requirements for indicators such as toluene, ethylbenzene, and xylene in student supplies, the supervision of these volatile toxic and harmful substances is basically in a state of absence, and the relevant detection methods are relatively lagging behind and cannot meet the supervision needs.

[0004] Moreover, the prior art method for detecting harmful substances in student supplies is time-consuming, inefficient, consumes a large amount of organic solvents, and cannot detect multiple volatile toxic and harmful substances at the same time, which is not conducive to rapid laboratory detection and rapid response to government supervision.

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