Liniment based on gene recombination protein Ta-hMsrA

A gene recombination and protein technology, which is used in skin care preparations, medical preparations containing active ingredients, cosmetics, etc. The effect of easy transportation and storage

Inactive Publication Date: 2019-08-30
WUHAN HUA PEPTIDE BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, the preparation of the above-mentioned proteins only stays in the laboratory stage, and large-scale mass production is difficult.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] (1) Emulsion configuration: Add the emulsification base commonly used in cosmetics into deionized water according to the conventional ratio, stir and mix, and mix well to form an emulsion.

[0035](2) Preliminary preparation of liniment: add the above components into the emulsion according to the ratio of 5% glycerin, 1% trehalose, and 0.1% surfactant, add water to the formulated amount, stir and mix evenly.

[0036] (3) Configuration of liniment: add 0.5% gene recombinant protein Ta-hMsrA lyophilized powder to the initial liniment, shake and mix, shake well; then add 3.5% gel, shake and mix, shake well, After being gelled, the liniment finished product is obtained.

Embodiment 2

[0038] (1) Emulsion configuration: add the emulsification base commonly used in cosmetics into purified water, stir and mix, and mix well to form an emulsion.

[0039] (2) Preliminary preparation of liniment: add the above components into the emulsion with the ratio of 35% glycerin, 2% trehalose and 0.4% surfactant according to 10% of the mass percentage of the emulsified matrix, and add water To the formula amount, stir to mix and mix.

[0040] (3) Configuration of liniment: add 1.5% gene recombinant protein Ta-hMsrA freeze-dried powder to the initial formulation of liniment, shake and mix, shake well; then add 0.5% gel, shake and mix, shake well, After being gelled, the liniment finished product is obtained.

Embodiment 3

[0042] (1) Emulsion configuration: add the emulsification base commonly used in cosmetics into purified water, stir and mix, and mix well to form an emulsion.

[0043] (2) Preliminary preparation of liniment: add the above components into the emulsion with the ratio of 30% glycerin, 4% trehalose, and 0.8% surfactant on the basis of 15% of the mass percentage of the emulsified matrix, and add water To the formula amount, stir to mix and mix.

[0044] (3) Configuration of liniment: add 3.5% gene recombinant protein Ta-hMsrA lyophilized powder to the initial liniment, shake and mix, shake well; then add 1.5% gel, shake and mix, shake well, After being gelled, the liniment finished product is obtained.

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PUM

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Abstract

The invention relates to a liniment based on gene recombination protein Ta-hMsrA. The liniment comprises gene recombination protein Ta-hMsrA. The liniment comprises the following components in percentage by mass of 5-35% of glycerine, 1-5% of trehalose, 0.5-3.5% of gelata, 0.5-5% of the gene recombination protein Ta-hMsrA, 0.1-1% of a surfactant and the balance emulsifying substrates and water. The liniment disclosed by the invention has the efficacy of resisting wrinkles, resisting oxidation and eliminating free radicals, can well maintain the activity of the gene recombination protein Ta-hMsrA and has enormous market prospects.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a liniment based on gene recombinant protein Ta-hMsrA. Background technique [0002] A large number of modern neuroscience studies have shown that pathological damage mediated by oxygen free radicals is involved in the occurrence and development of a variety of major diseases of the nervous system. The brain's rich lipid content and relative lack of antioxidant enzyme levels make it more vulnerable to oxidative stress. Various factors (such as abnormally folded protein accumulation, ischemia-reperfusion injury, etc.) induce neurons to produce more reactive oxygen species (ROS) through pathways such as mitochondrial aerobic respiration, such as O 2- ., H 2 o 2 , OH and 1 o 2 , and the aging process is often accompanied by the weakening of ROS scavenging system (such as glutathione reduction system, superoxide dismutase, etc.), which leads to the abnormal accumul...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/64A61K8/34A61K8/60A61K8/67A61Q19/00A61Q19/08
CPCA61K8/345A61K8/60A61K8/64A61K8/678A61K8/735A61K2800/72A61Q19/00A61Q19/08
Inventor 曾建华闫云云胡雪平
Owner WUHAN HUA PEPTIDE BIOLOGICAL TECH CO LTD
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