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A kind of multi-purpose photonic cryogel and preparation method thereof

A technology of cold gel and photon, which is applied in the fields of medical cosmetology and biomedicine, can solve the problems of low light transmittance of photon cold gel, damaged probe, insufficient moisturizing type, etc., and achieves easy preparation method, non-irritating, good The effect of light transmittance

Active Publication Date: 2021-12-14
王月玲 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, photonic cold gels generally have disadvantages such as low light transmittance, weak thermal conductivity, insufficient moisturizing type, not easy to remove, and damage to the probe. Therefore, the use of photonic cold gels in the field of injection beauty technology has a large market demand and economical considerable benefits

Method used

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  • A kind of multi-purpose photonic cryogel and preparation method thereof
  • A kind of multi-purpose photonic cryogel and preparation method thereof
  • A kind of multi-purpose photonic cryogel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Add 6L of polyglycolide (intrinsic viscosity: 0.4dl / g) dichloromethane solution with a mass concentration of 2% to 20L of polyvinyl alcohol 1788 (low viscosity type) aqueous solution with a mass concentration of 0.2%, and stir for 3 hours. The stirring speed is 350rpm, and the mixture in the reactor is released. Suction filtration, vacuum drying, ready for filling.

[0052] Mix 0.1 part of carbomer, 1 part of polyethylene glycol and 1 part of glycerin, stir evenly, add 50 parts of water for injection, stir, after completely swelling, add 0.5 part of ethyl p-hydroxybenzoate, 0.1 part of triethanolamine, and then Add the remaining water for injection, continue to stir for 1 hour, add 5 parts of PLGA microspheres, continue to stir for 2 hours, and obtain.

Embodiment 2

[0054] Add 10L of 5% polyvinyl alcohol (intrinsic viscosity: 1.0dl / g) chloroform solution to 10L of polyvinyl alcohol 1788 (low viscosity type) aqueous solution with a mass concentration of 0.5%, and stir for 8 hours at a stirring speed of 500rpm , release the mixture in the reactor. Suction filtration, vacuum drying, ready for filling.

[0055] Mix 5 parts of carbomer, 10 parts of polyethylene glycol and 5 parts of mannitol, stir evenly, add 50 parts of water for injection, stir, after swelling completely, add the remaining water for injection, adjust with hydrochloric acid solution or sodium hydroxide solution When the pH reaches 6.8, after stirring for 1 hour, add 15 parts of PLGA microspheres and continue stirring for 2 hours to obtain the product.

Embodiment 3

[0057] Add 15L of polyethylene lactide (intrinsic viscosity: 2.0dl / g) ethyl acetate solution with a mass concentration of 10% to 20L of polyvinyl alcohol 1788 (low viscosity type) aqueous solution with a mass concentration of 1.0%, and stir for 15 hours. The stirring speed is 650rpm, and the mixture in the reaction kettle is released; it is filtered, vacuum-dried, and prepared for filling.

[0058] Mix 1.5 parts of carbomer, 5 parts of polyethylene glycol and 5 parts of glycerin, stir evenly, add 50 parts of water for injection, stir, after completely swelling, add 0.3 parts of ethyl p-hydroxybenzoate, 0.5 parts of triethanolamine, and then Add the remaining water for injection, continue to stir for 1 hour, then add 30 parts of PLGA microspheres, continue to stir for 2 hours to obtain the product.

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Abstract

The invention relates to a multipurpose photon cold gel and a preparation method thereof, belonging to the technical fields of medical cosmetology and biomedicine. The multipurpose photonic cold gel provided by the invention mainly includes the following components in parts by weight: 2 to 50 parts of polyglycolide; 0.1 to 5 parts of carbomer; 1 to 10 parts of polyethylene glycol; Regulator 1-10 parts; pH regulator 0.1-2 parts; bacteriostatic agent 0.05-0.5 parts; water for injection added to 100 parts. The multi-purpose photonic cold gel prepared by the present invention can be used as a coating agent for laser cosmetics, and can also be used as an injection cosmetic, with good biocompatibility, no cytotoxicity, no skin irritation, no sensitization, etc., and The preparation method is easy to operate and convenient to realize industrial production.

Description

technical field [0001] The invention belongs to the technical fields of medical cosmetology and biomedicine, and in particular relates to a multipurpose photonic cold gel and a preparation method thereof. Background technique [0002] With the improvement of today's material living standards, more and more people will pay more attention to their quality of life and the pursuit of beauty, which makes my country's cosmetic surgery industry will gradually enter a stage of rapid development. It has become a common phenomenon to correct soft tissue defects and repair aging and wrinkled skin through plastic surgery technology, so as to maintain the perfect and youthful facial shape. [0003] Among various plastic surgery techniques, injection beauty technology accounts for the largest proportion, accounting for about 40% of the entire beauty market. Injection beauty technology is a beauty technology that partially modifies the human body through injection to achieve exquisite loc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/18A61L27/16A61L27/50A61L27/52A61L27/58A61K41/00
CPCA61L27/18A61L27/16A61L27/52A61L27/50A61L27/58A61K41/00A61L2400/06C08L67/04C08L33/02
Inventor 王月玲
Owner 王月玲